Genular: Defining Cellular Identity and Function

Details for: Sox1

Gene ID: 20664

Symbol: Sox1

Ensembl ID: ENSMUSG00000096014

Description: SRY (sex determining region Y)-box 1

Associated with

Brain development
(GO:0007420)
Cellular response to leukemia inhibitory factor
(GO:1990830)
Dna-binding transcription activator activity, rna polymerase ii-specific
(GO:0001228)
Dna binding
(GO:0003677)
Forebrain development
(GO:0030900)
Forebrain neuron development
(GO:0021884)
Forebrain neuron differentiation
(GO:0021879)
Interneuron migration
(GO:1904936)
Lens morphogenesis in camera-type eye
(GO:0002089)
Negative regulation of transcription by rna polymerase ii
(GO:0000122)
Neuron differentiation
(GO:0030182)
Neuron migration
(GO:0001764)
Nucleoplasm
(GO:0005654)
Nucleus
(GO:0005634)
Positive regulation of transcription by rna polymerase ii
(GO:0045944)
Protein binding
(GO:0005515)
Regulation of dna-templated transcription
(GO:0006355)
Regulation of oligodendrocyte differentiation
(GO:0048713)
Rna polymerase ii cis-regulatory region sequence-specific dna binding
(GO:0000978)
Sequence-specific dna binding
(GO:0043565)
Ventral spinal cord interneuron specification
(GO:0021521)

Other Information

Proteins

Transcription factor SOX-1

Genular Protein ID: 2099595454

Symbol: SOX1_MOUSE

Name: Transcription factor SOX-1

UniProtKB Accession Codes:

P53783 Q80XF2

Database IDs:

Citations:

PubMed ID: 8625802

Title: A comparison of the properties of Sox-3 with Sry and two related genes, Sox-1 and Sox-2.

PubMed ID: 8625802

DOI: 10.1242/dev.122.2.509

PubMed ID: 15456859

Title: Interplay of SOX and POU factors in regulation of the nestin gene in neural primordial cells.

PubMed ID: 15456859

DOI: 10.1128/mcb.24.20.8834-8846.2004

PubMed ID: 19468303

Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.

PubMed ID: 19468303

DOI: 10.1371/journal.pbio.1000112

Sequence Information:

Length: 391
Mass: 39053
Checksum: EA88F7C49E30BDA8
Sequence:

MYSMMMETDL HSPGGAQAPT NLSGPAGAGG GGGGGGGGGG GGGTKANQDR VKRPMNAFMV 
WSRGQRRKMA QENPKMHNSE ISKRLGAEWK VMSEAEKRPF IDEAKRLRAL HMKEHPDYKY 
RPRRKTKTLL KKDKYSLAGG LLAAGAGGGG AAVAMGVGVG VGAAAVGQRL ESPGGAAGGG 
YAHVNGWANG AYPGSVAAAA AAAAMMQEAQ LAYGQHPGAG GAHPHAHPAH PHPHHPHAHP 
HNPQPMHRYD MGALQYSPIS NSQGYMSASP SGYGGIPYGA AAAAAAAAGG AHQNSAVAAA 
AAAAAASSGA LGALGSLVKS EPSGSPPAPA HSRAPCPGDL REMISMYLPA GEGGDPAAAA 
AAAAQSRLHS LPQHYQGAGA GVNGTVPLTH I

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.