Details for: Sox15

Gene ID: 20670

Symbol: Sox15

Ensembl ID: ENSMUSG00000041287

Description: SRY (sex determining region Y)-box 15

Associated with

  • Brain development
    (GO:0007420)
  • Cell differentiation
    (GO:0030154)
  • Chromatin binding
    (GO:0003682)
  • Cytoplasm
    (GO:0005737)
  • Dna-binding transcription activator activity, rna polymerase ii-specific
    (GO:0001228)
  • Dna-binding transcription factor activity, rna polymerase ii-specific
    (GO:0000981)
  • Dna binding
    (GO:0003677)
  • Myoblast development
    (GO:0048627)
  • Negative regulation of striated muscle tissue development
    (GO:0045843)
  • Negative regulation of transcription by rna polymerase ii
    (GO:0000122)
  • Neuron differentiation
    (GO:0030182)
  • Nucleus
    (GO:0005634)
  • Positive regulation of g0 to g1 transition
    (GO:0070318)
  • Positive regulation of myoblast proliferation
    (GO:2000288)
  • Positive regulation of satellite cell activation involved in skeletal muscle regeneration
    (GO:0014718)
  • Positive regulation of transcription by rna polymerase ii
    (GO:0045944)
  • Protein binding
    (GO:0005515)
  • Rna polymerase ii cis-regulatory region sequence-specific dna binding
    (GO:0000978)
  • Skeletal muscle tissue regeneration
    (GO:0043403)
  • Transcription regulator complex
    (GO:0005667)
  • Trophoblast giant cell differentiation
    (GO:0060707)

Other Information

Genular Protein ID: 214093749

Symbol: SOX15_MOUSE

Name: Protein SOX-15

UniProtKB Accession Codes:

P43267 O70204 P70418 Q62246 Q91V00 Q91V43 Q920T1 Q9JLG2

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 CCDS 1 CDD 1 CTD 1 DNASU 1 EMBL 14 Ensembl 1 ExpressionAtlas 1 GO 18 Gene3D 1 GeneTree 1 Genevisible 1 HOGENOM 1 InParanoid 1 IntAct 1 InterPro 2 KEGG 1 MGI 1 MINT 1 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 PIR 1 PRO 1 PROSITE 1 PROSITE-ProRule 1 PaxDb 1 Pfam 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 RNAct 1 RefSeq 1 SAM 1 SMART 1 SMR 1 STRING 1 SUPFAM 1 TreeFam 1 UCSC 1 UniProtKB 1 VEuPathDB 1 eggNOG 1

Citations:

PubMed ID: 10524236

Title: Five different genes, Eif4a1, Cd68, Supl15h, Sox15 and Fxr2h, are clustered in a 40 kb region of mouse chromosome 11.

PubMed ID: 10524236

DOI: 10.1016/s0378-1119(99)00301-7

PubMed ID: 10821863

Title: Muscle differentiation is antagonized by SOX15, a new member of the SOX protein family.

PubMed ID: 10821863

DOI: 10.1074/jbc.275.21.16103

PubMed ID: 8921394

Title: Numerous members of the Sox family of HMG box-containing genes are expressed in developing mouse teeth.

PubMed ID: 8921394

DOI: 10.1006/geno.1996.0548

PubMed ID: 8479922

Title: Sox 15, a novel member of the murine Sox family of HMG box transcription factors.

PubMed ID: 8479922

DOI: 10.1093/nar/21.7.1669

PubMed ID: 15367664

Title: Sox15 is required for skeletal muscle regeneration.

PubMed ID: 15367664

DOI: 10.1128/mcb.24.19.8428-8436.2004

PubMed ID: 15863505

Title: Differential roles for Sox15 and Sox2 in transcriptional control in mouse embryonic stem cells.

PubMed ID: 15863505

DOI: 10.1074/jbc.m501423200

PubMed ID: 16759287

Title: Sox15 enhances trophoblast giant cell differentiation induced by Hand1 in mouse placenta.

PubMed ID: 16759287

DOI: 10.1111/j.1432-0436.2006.00070.x

PubMed ID: 17363903

Title: Sox15 and Fhl3 transcriptionally coactivate Foxk1 and regulate myogenic progenitor cells.

PubMed ID: 17363903

DOI: 10.1038/sj.emboj.7601635

Sequence Information:

  • Length: 231
  • Mass: 25311
  • Checksum: FCFE87C3BB458645
  • Sequence:
    • MALTSSSQAE TWSLHPRAST ASLPLGPQEQ EAGGSPGASG GLPLEKVKRP MNAFMVWSSV 
QRRQMAQQNP KMHNSEISKR LGAQWKLLGD EEKRPFVEEA KRLRARHLRD YPDYKYRPRR 
KSKNSSTGSV PFSQEGGGLA CGGSHWGPGY TTTQGSRGFG YQPPNYSTAY LPGSYTSSHC 
RPEAPLPCTF PQSDPRLQGE LRPSFSPYLS PDSSTPYNTS LAGAPMPVTH L

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.