Details for: Sox6

Gene ID: 20679

Symbol: Sox6

Ensembl ID: ENSMUSG00000051910

Description: SRY (sex determining region Y)-box 6

Associated with

Other Information

Genular Protein ID: 4037010298

Symbol: SOX6_MOUSE

Name: N/A

UniProtKB Accession Codes:

P40645 Q62250 Q9QWS5

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 CCDS 1 CDD 1 CTD 1 ChiTaRS 1 DNASU 1 EMBL 4 Ensembl 2 ExpressionAtlas 1 GO 44 Gene3D 1 GeneTree 1 Genevisible 1 InParanoid 1 IntAct 1 InterPro 2 KEGG 1 MGI 2 MINT 1 MaxQB 1 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 PIR 2 PRO 1 PROSITE 1 PROSITE-ProRule 1 PaxDb 1 Pfam 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 2 RNAct 1 Reactome 1 RefSeq 5 SAM 1 SMART 1 SMR 1 STRING 1 SUPFAM 1 TreeFam 1 UCSC 2 UniProtKB 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1

Citations:

PubMed ID: 7567444

Title: The Sry-related HMG box-containing gene Sox6 is expressed in the adult testis and developing nervous system of the mouse.

PubMed ID: 7567444

DOI: 10.1093/nar/23.17.3365

PubMed ID: 7791783

Title: A gene that is related to SRY and is expressed in the testes encodes a leucine zipper-containing protein.

PubMed ID: 7791783

DOI: 10.1128/mcb.15.7.3759

PubMed ID: 9755172

Title: A new long form of Sox5 (L-Sox5), Sox6 and Sox9 are coexpressed in chondrogenesis and cooperatively activate the type II collagen gene.

PubMed ID: 9755172

DOI: 10.1093/emboj/17.19.5718

PubMed ID: 1614875

Title: A conserved family of genes related to the testis determining gene, SRY.

PubMed ID: 1614875

DOI: 10.1093/nar/20.11.2887

PubMed ID: 10996314

Title: Characterization of Solt, a novel SoxLZ/Sox6 binding protein expressed in adult mouse testis.

PubMed ID: 10996314

DOI: 10.1016/s0014-5793(00)01987-6

PubMed ID: 11702786

Title: The transcription factors L-Sox5 and Sox6 are essential for cartilage formation.

PubMed ID: 11702786

DOI: 10.1016/s1534-5807(01)00003-x

PubMed ID: 12414734

Title: The transcription factor Sox9 has essential roles in successive steps of the chondrocyte differentiation pathway and is required for expression of Sox5 and Sox6.

PubMed ID: 12414734

DOI: 10.1101/gad.1017802

PubMed ID: 14530442

Title: Sox6 regulation of cardiac myocyte development.

PubMed ID: 14530442

DOI: 10.1093/nar/gkg807

PubMed ID: 15529345

Title: The combination of SOX5, SOX6, and SOX9 (the SOX trio) provides signals sufficient for induction of permanent cartilage.

PubMed ID: 15529345

DOI: 10.1002/art.20611

PubMed ID: 14993235

Title: Sox5 and Sox6 are needed to develop and maintain source, columnar, and hypertrophic chondrocytes in the cartilage growth plate.

PubMed ID: 14993235

DOI: 10.1083/jcb.200312045

PubMed ID: 17242355

Title: Large-scale phosphorylation analysis of mouse liver.

PubMed ID: 17242355

DOI: 10.1073/pnas.0609836104

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 26150426

Title: The transcription factors SOX9 and SOX5/SOX6 cooperate genome-wide through super-enhancers to drive chondrogenesis.

PubMed ID: 26150426

DOI: 10.1093/nar/gkv688

PubMed ID: 26525805

Title: Sox13 functionally complements the related Sox5 and Sox6 as important developmental modulators in mouse spinal cord oligodendrocytes.

PubMed ID: 26525805

DOI: 10.1111/jnc.13414

PubMed ID: 27923061

Title: Comparative Transcriptomic and Epigenomic Analyses Reveal New Regulators of Murine Brown Adipogenesis.

PubMed ID: 27923061

DOI: 10.1371/journal.pgen.1006474

PubMed ID: 32442410

Title: De Novo SOX6 Variants Cause a Neurodevelopmental Syndrome Associated with ADHD, Craniosynostosis, and Osteochondromas.

PubMed ID: 32442410

DOI: 10.1016/j.ajhg.2020.04.015

Sequence Information:

  • Length: 827
  • Mass: 91803
  • Checksum: F777BAB7CFB1E93B
  • Sequence:
    • MSSKQATSPF ACTADGEEAM TQDLTSREKE EGSDQHPASH LPLHPIMHNK PHSEELPTLV 
STIQQDADWD SVLSSQQRME SENNKLCSLY SFRNTSTSPH KPDEGSRERE IMNSVTFGTP 
ERRKGSLADV VDTLKQKKLE EMTRTEQEDS SCMEKLLSKD WKEKMERLNT SELLGEIKGT 
PESLAEKERQ LSTMITQLIS LREQLLAAHD EQKKLAASQI EKQRQQMDLA RQQQEQIARQ 
QQQLLQQQHK INLLQQQIQV QGHMPPLMIP IFPHDQRTLA AAAAAQQGFL FPPGITYKPG 
DNYPVQFIPS TMAAAAASGL SPLQLQKGHV SHPQINPRLK GISDRFGRNL DPSEHGGGHS 
YNHRQIEQLY AAQLASMQVS PGAKMPSTPQ PPNSAGAVSP TGIKNEKRGT SPVTQVKDET 
TAQPLNLSSR PKTAEPVKSP TSPTQNLFPA SKTSPVNLPN KSSIPSPIGG SLGRGSSLDI 
LSSLNSPALF GDQDTVMKAI QEARKMREQI QREQQQQPHG VDGKLSSMNN MGLSNCRTEK 
ERTRFENLGP QLTGKSSEDG KLGPGVIDLT RPEDAEGSKA MNGSAAKLQQ YYCWPTGGAT 
VAEARVYRDA RGRASSEPHI KRPMNAFMVW AKDERRKILQ AFPDMHNSNI SKILGSRWKS 
MSNQEKQPYY EEQARLSKIH LEKYPNYKYK PRPKRTCIVD GKKLRIGEYK QLMRSRRQEM 
RQFFTVGQQP QMPITTGTGV VYPGAITMAT TTPSPQMTSD CSSTSASPEP SLPVIQSTYG 
MKMDGASLAG NDMINGEDEM EAYDDYEDDP KSDYSSENEA PEPVSAN

Genular Protein ID: 1614508102

Symbol: A0A0U1RNW8_MOUSE

Name: N/A

UniProtKB Accession Codes:

A0A0U1RNW8

Database IDs:

AGR 1 ARBA 4 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CDD 1 CTD 1 ChiTaRS 1 DNASU 1 Ensembl 3 ExpressionAtlas 1 GO 9 Gene3D 1 GeneTree 1 InterPro 2 MGI 2 MaxQB 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 2 PROSITE-ProRule 1 PeptideAtlas 1 Pfam 1 Proteomes 2 ProteomicsDB 1 RefSeq 14 SAM 2 SMART 1 SMR 1 SUPFAM 1 VEuPathDB 1

Citations:

PubMed ID: 17242355

Title: Large-scale phosphorylation analysis of mouse liver.

PubMed ID: 17242355

DOI: 10.1073/pnas.0609836104

PubMed ID: 19468303

Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.

PubMed ID: 19468303

DOI: 10.1371/journal.pbio.1000112

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

Sequence Information:

  • Length: 828
  • Mass: 91931
  • Checksum: D26B65D348325477
  • Sequence:
    • MSSKQATSPF ACTADGEEAM TQDLTSREKE EGSDQHPASH LPLHPIMHNK PHSEELPTLV 
STIQQDADWD SVLSSQQRME SENNKLCSLY SFRNTSTSPH KPDEGSRERE IMNSVTFGTP 
ERRKGSLADV VDTLKQKKLE EMTRTEQEDS SCMEKLLSKD WKEKMERLNT SELLGEIKGT 
PESLAEKERQ LSTMITQLIS LREQLLAAHD EQKKLAASQI EKQRQQMDLA RQQQEQIARQ 
QQQLLQQQHK INLLQQQIQQ VQGHMPPLMI PIFPHDQRTL AAAAAAQQGF LFPPGITYKP 
GDNYPVQFIP STMAAAAASG LSPLQLQKGH VSHPQINPRL KGISDRFGRN LDPSEHGGGH 
SYNHRQIEQL YAAQLASMQV SPGAKMPSTP QPPNSAGAVS PTGIKNEKRG TSPVTQVKDE 
TTAQPLNLSS RPKTAEPVKS PTSPTQNLFP ASKTSPVNLP NKSSIPSPIG GSLGRGSSLD 
ILSSLNSPAL FGDQDTVMKA IQEARKMREQ IQREQQQQPH GVDGKLSSMN NMGLSNCRTE 
KERTRFENLG PQLTGKSSED GKLGPGVIDL TRPEDAEGSK AMNGSAAKLQ QYYCWPTGGA 
TVAEARVYRD ARGRASSEPH IKRPMNAFMV WAKDERRKIL QAFPDMHNSN ISKILGSRWK 
SMSNQEKQPY YEEQARLSKI HLEKYPNYKY KPRPKRTCIV DGKKLRIGEY KQLMRSRRQE 
MRQFFTVGQQ PQMPITTGTG VVYPGAITMA TTTPSPQMTS DCSSTSASPE PSLPVIQSTY 
GMKMDGASLA GNDMINGEDE MEAYDDYEDD PKSDYSSENE APEPVSAN

Genular Protein ID: 2553467413

Symbol: E9PUW0_MOUSE

Name: N/A

UniProtKB Accession Codes:

E9PUW0

Database IDs:

AGR 1 ARBA 4 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CDD 1 CTD 1 ChiTaRS 1 DNASU 1 Ensembl 3 ExpressionAtlas 1 GO 2 Gene3D 1 GeneTree 1 HOGENOM 1 InterPro 2 MGI 2 MaxQB 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 2 PROSITE-ProRule 1 PeptideAtlas 1 Pfam 1 Proteomes 2 ProteomicsDB 1 RefSeq 3 SAM 2 SMART 1 SMR 1 SUPFAM 1 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 17242355

Title: Large-scale phosphorylation analysis of mouse liver.

PubMed ID: 17242355

DOI: 10.1073/pnas.0609836104

PubMed ID: 19468303

Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.

PubMed ID: 19468303

DOI: 10.1371/journal.pbio.1000112

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

Sequence Information:

  • Length: 787
  • Mass: 87320
  • Checksum: B4C1BDC3186FCF89
  • Sequence:
    • MSSKQATSPF ACTADGEEAM TQDLTSREKE EGSDQHPASH LPLHPIMHNK PHSEELPTLV 
STIQQDADWD SVLSSQQRME SENNKLCSLY SFRNTSTSPH KPDEGSRERE IMNSVTFGTP 
ERRKGSLADV VDTLKQKKLE EMTRTEQEDS SCMEKLLSKD WKEKMERLNT SELLGEIKGT 
PESLAEKERQ LSTMITQLIS LREQLLAAHD EQKKLAASQI EKQRQQMDLA RQQQEQIARQ 
QQQLLQQQHK INLLQQQIQQ VQGHMPPLMI PIFPHDQRTL AAAAAAQQGF LFPPGITYKP 
GDNYPVQFIP STMAAAAASG LSPLQLQQLY AAQLASMQVS PGAKMPSTPQ PPNSAGAVSP 
TGIKNEKRGT SPVTQVKDET TAQPLNLSSR PKTAEPVKSP TSPTQNLFPA SKTSPVNLPN 
KSSIPSPIGG SLGRGSSLDI LSSLNSPALF GDQDTVMKAI QEARKMREQI QREQQQQPHG 
VDGKLSSMNN MGLSNCRTEK ERTRFENLGP QLTGKSSEDG KLGPGVIDLT RPEDAEGSKA 
MNGSAAKLQQ YYCWPTGGAT VAEARVYRDA RGRASSEPHI KRPMNAFMVW AKDERRKILQ 
AFPDMHNSNI SKILGSRWKS MSNQEKQPYY EEQARLSKIH LEKYPNYKYK PRPKRTCIVD 
GKKLRIGEYK QLMRSRRQEM RQFFTVGQQP QMPITTGTGV VYPGAITMAT TTPSPQMTSD 
CSSTSASPEP SLPVIQSTYG MKMDGASLAG NDMINGEDEM EAYDDYEDDP KSDYSSENEA 
PEPVSAN

Genular Protein ID: 1575062603

Symbol: Q8BSS6_MOUSE

Name: N/A

UniProtKB Accession Codes:

Q8BSS6

Database IDs:

AGR 1 ARBA 4 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CDD 1 CTD 1 ChiTaRS 1 DNASU 1 EMBL 2 Ensembl 2 ExpressionAtlas 1 GO 2 Gene3D 1 GeneTree 1 InterPro 2 KEGG 1 MGI 2 MaxQB 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 2 PROSITE-ProRule 1 PeptideAtlas 1 Pfam 1 Proteomes 2 ProteomicsDB 1 RefSeq 7 SAM 2 SMART 1 SMR 1 SUPFAM 1 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 10349636

Title: High-efficiency full-length cDNA cloning.

PubMed ID: 10349636

DOI: 10.1016/S0076-6879(99)03004-9

PubMed ID: 11042159

Title: Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes.

PubMed ID: 11042159

DOI: 10.1101/gr.145100

PubMed ID: 11076861

Title: RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer.

PubMed ID: 11076861

DOI: 10.1101/gr.152600

PubMed ID: 11217851

Title: Functional annotation of a full-length mouse cDNA collection.

PubMed ID: 11217851

DOI: 10.1038/35055500

PubMed ID: 12466851

Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.

PubMed ID: 12466851

DOI: 10.1038/nature01266

PubMed ID: 16141073

Title: Antisense Transcription in the Mammalian Transcriptome.

PubMed ID: 16141073

DOI: 10.1126/science.1112009

PubMed ID: 17242355

Title: Large-scale phosphorylation analysis of mouse liver.

PubMed ID: 17242355

DOI: 10.1073/pnas.0609836104

PubMed ID: 19468303

Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.

PubMed ID: 19468303

DOI: 10.1371/journal.pbio.1000112

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

Sequence Information:

  • Length: 785
  • Mass: 87064
  • Checksum: BD9FA455A8800DC9
  • Sequence:
    • MSSKQATSPF ACTADGEEAM TQDLTSREKE EGSDQHPASH LPLHPIMHNK PHSEELPTLV 
STIQQDADWD SVLSSQQRME SENNKLCSLY SFRNTSTSPH KPDEGSRERE IMNSVTFGTP 
ERRKGSLADV VDTLKQKKLE EMTRTEQEDS SCMEKLLSKD WKEKMERLNT SELLGEIKGT 
PESLAEKERQ LSTMITQLIS LREQLLAAHD EQKKLAASQI EKQRQQMDLA RQQQEQIARQ 
QQQLLQQQHK INLLQQQIQV QGHMPPLMIP IFPHDQRTLA AAAAAQQGFL FPPGITYKPG 
DNYPVQFIPS TMAAAAASGL SPLQLQLYAA QLASMQVSPG AKMPSTPQPP NSAGAVSPTG 
IKNEKRGTSP VTQVKDETTA QPLNLSSRPK TAEPVKSPTS PTQNLFPASK TSPVNLPNKS 
SIPSPIGGSL GRGSSLDILS SLNSPALFGD QDTVMKAIQE ARKMREQIQR EQQQQPHGVD 
GKLSSMNNMG LSNCRTEKER TRFENLGPQL TGKSSEDGKL GPGVIDLTRP EDAEGSKAMN 
GSAAKLQQYY CWPTGGATVA EARVYRDARG RASSEPHIKR PMNAFMVWAK DERRKILQAF 
PDMHNSNISK ILGSRWKSMS NQEKQPYYEE QARLSKIHLE KYPNYKYKPR PKRTCIVDGK 
KLRIGEYKQL MRSRRQEMRQ FFTVGQQPQM PITTGTGVVY PGAITMATTT PSPQMTSDCS 
STSASPEPSL PVIQSTYGMK MDGASLAGND MINGEDEMEA YDDYEDDPKS DYSSENEAPE 
PVSAN

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.