Details for: Sox7

Gene ID: 20680

Symbol: Sox7

Ensembl ID: ENSMUSG00000063060

Description: SRY (sex determining region Y)-box 7

Associated with

  • Deactivation of the beta-catenin transactivating complex
    (R-MMU-3769402)
  • Signaling by wnt
    (R-MMU-195721)
  • Signal transduction
    (R-MMU-162582)
  • Tcf dependent signaling in response to wnt
    (R-MMU-201681)
  • Cell differentiation
    (GO:0030154)
  • Cytoplasm
    (GO:0005737)
  • Dna-binding transcription activator activity, rna polymerase ii-specific
    (GO:0001228)
  • Dna-binding transcription factor activity
    (GO:0003700)
  • Dna-binding transcription factor activity, rna polymerase ii-specific
    (GO:0000981)
  • Dna binding
    (GO:0003677)
  • Endoderm formation
    (GO:0001706)
  • Negative regulation of cell population proliferation
    (GO:0008285)
  • Negative regulation of dna-templated transcription
    (GO:0045892)
  • Nucleus
    (GO:0005634)
  • Positive regulation of cysteine-type endopeptidase activity involved in apoptotic process
    (GO:0043280)
  • Positive regulation of dna-templated transcription
    (GO:0045893)
  • Positive regulation of transcription by rna polymerase ii
    (GO:0045944)
  • Regulation of canonical wnt signaling pathway
    (GO:0060828)
  • Regulation of transcription by rna polymerase ii
    (GO:0006357)
  • Rna polymerase ii cis-regulatory region sequence-specific dna binding
    (GO:0000978)
  • Sequence-specific dna binding
    (GO:0043565)
  • Sequence-specific double-stranded dna binding
    (GO:1990837)
  • Transcription cis-regulatory region binding
    (GO:0000976)

Other Information

Genular Protein ID: 3999292872

Symbol: SOX7_MOUSE

Name: Transcription factor SOX-7

UniProtKB Accession Codes:

P40646 Q9R1T6

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CCDS 1 CDD 1 CTD 1 DNASU 1 EMBL 2 Ensembl 1 ExpressionAtlas 1 GO 17 Gene3D 1 GeneTree 1 Genevisible 1 HOGENOM 1 InParanoid 1 InterPro 4 KEGG 1 MGI 1 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 PIR 1 PRO 1 PROSITE 2 PROSITE-ProRule 2 PaxDb 1 Pfam 2 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 RNAct 1 Reactome 1 RefSeq 1 SAM 1 SMART 1 SMR 1 STRING 1 SUPFAM 1 UCSC 1 VEuPathDB 1 eggNOG 1

Citations:

PubMed ID: 10320775

Title: Isolation and characterization of a mouse SRY-related cDNA, mSox7.

PubMed ID: 10320775

DOI: 10.1016/s0167-4781(99)00047-0

PubMed ID: 1614875

Title: A conserved family of genes related to the testis determining gene, SRY.

PubMed ID: 1614875

DOI: 10.1093/nar/20.11.2887

PubMed ID: 11691915

Title: SOX7 transcription factor: sequence, chromosomal localisation, expression, transactivation and interference with Wnt signalling.

PubMed ID: 11691915

DOI: 10.1093/nar/29.21.4274

PubMed ID: 15082719

Title: SOX7 and GATA-4 are competitive activators of Fgf-3 transcription.

PubMed ID: 15082719

DOI: 10.1074/jbc.m313814200

PubMed ID: 19801444

Title: Sox7-sustained expression alters the balance between proliferation and differentiation of hematopoietic progenitors at the onset of blood specification.

PubMed ID: 19801444

DOI: 10.1182/blood-2009-06-226290

PubMed ID: 19489079

Title: SOX15 and SOX7 differentially regulate the myogenic program in P19 cells.

PubMed ID: 19489079

DOI: 10.1002/stem.57

PubMed ID: 22492353

Title: SOX7 regulates the expression of VE-cadherin in the haemogenic endothelium at the onset of haematopoietic development.

PubMed ID: 22492353

DOI: 10.1242/dev.071282

Sequence Information:

  • Length: 380
  • Mass: 41489
  • Checksum: BE780D7234CB895C
  • Sequence:
    • MASLLGAYPW TEGLECPALE AELSDGLSPP AVPRPSGDKS SESRIRRPMN AFMVWAKDER 
KRLAVQNPDL HNAELSKMLG KSWKALTLSQ KRPYVDEAER LRLQHMQDYP NYKYRPRRKK 
QGKRLCKRVD PGFLLSSLSR DQNTLPEKNG IGRGEKEDRG EYSPGATLPG LHSCYREGAA 
AAPGSVDTYP YGLPTPPEMS PLDALEPEQT FFSSSCQEEH GHPHHLPHLP GPPYSPEFTP 
SPLHCSHPLG SLALGQSPGV SMMSSVSGCP PSPAYYSHAT YHPLHPNLQA HLGQLSPPPE 
HPGFDTLDQL SQVELLGDMD RNEFDQYLNT PGHPDSAAGV GTLTGHVPLS QGTPTGPTET 
SLISVLADAT ATYYNSYSVS

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.