Genular: Defining Cellular Identity and Function

Details for: Sox8

Gene ID: 20681

Symbol: Sox8

Ensembl ID: ENSMUSG00000024176

Description: SRY (sex determining region Y)-box 8

Associated with

Adipose tissue development
(GO:0060612)
Astrocyte fate commitment
(GO:0060018)
Cell fate commitment
(GO:0045165)
Cell maturation
(GO:0048469)
Cis-regulatory region sequence-specific dna binding
(GO:0000987)
Cytoplasm
(GO:0005737)
Dna-binding transcription factor activity
(GO:0003700)
Dna-binding transcription factor activity, rna polymerase ii-specific
(GO:0000981)
Dna-binding transcription factor binding
(GO:0140297)
Dna binding
(GO:0003677)
Enteric nervous system development
(GO:0048484)
Fat cell differentiation
(GO:0045444)
In utero embryonic development
(GO:0001701)
Male gonad development
(GO:0008584)
Metanephric nephron tubule formation
(GO:0072289)
Morphogenesis of a branching epithelium
(GO:0061138)
Morphogenesis of an epithelium
(GO:0002009)
Negative regulation of apoptotic process
(GO:0043066)
Negative regulation of dna-templated transcription
(GO:0045892)
Negative regulation of myoblast differentiation
(GO:0045662)
Negative regulation of photoreceptor cell differentiation
(GO:0046533)
Negative regulation of transcription by rna polymerase ii
(GO:0000122)
Neural crest cell development
(GO:0014032)
Neural crest cell migration
(GO:0001755)
Nucleus
(GO:0005634)
Oligodendrocyte differentiation
(GO:0048709)
Osteoblast differentiation
(GO:0001649)
Peripheral nervous system development
(GO:0007422)
Positive regulation of branching involved in ureteric bud morphogenesis
(GO:0090190)
Positive regulation of dna-templated transcription
(GO:0045893)
Positive regulation of gene expression
(GO:0010628)
Positive regulation of gliogenesis
(GO:0014015)
Positive regulation of kidney development
(GO:0090184)
Positive regulation of osteoblast proliferation
(GO:0033690)
Positive regulation of transcription by rna polymerase ii
(GO:0045944)
Protein binding
(GO:0005515)
Regulation of hormone levels
(GO:0010817)
Renal vesicle induction
(GO:0072034)
Retina development in camera-type eye
(GO:0060041)
Retinal rod cell differentiation
(GO:0060221)
Rna polymerase ii cis-regulatory region sequence-specific dna binding
(GO:0000978)
Sequence-specific dna binding
(GO:0043565)
Sequence-specific double-stranded dna binding
(GO:1990837)
Sertoli cell development
(GO:0060009)
Signal transduction
(GO:0007165)
Skeletal muscle cell differentiation
(GO:0035914)
Spermatogenesis
(GO:0007283)
Transcription regulator complex
(GO:0005667)
Ureter morphogenesis
(GO:0072197)

Other Information

Proteins

SOX8_MOUSE

Genular Protein ID: 1441524944

Symbol: SOX8_MOUSE

Name: N/A

UniProtKB Accession Codes:

Q04886

Database IDs:

Citations:

PubMed ID: 10684944

Title: Cloning and characterisation of the Sry-related transcription factor gene Sox8.

PubMed ID: 10684944

DOI: 10.1093/nar/28.6.1473

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 8441686

Title: Seven new members of the Sox gene family expressed during mouse development.

PubMed ID: 8441686

DOI: 10.1093/nar/21.3.744

Sequence Information:

Length: 464
Mass: 49879
Checksum: 3C080629F58F5AB5
Sequence:

MLDMSEARAQ PPCSPSGTAS SMSHVEDSDS DAPPSPAGSE GLGRAGGGGR GDTAEAADER 
FPACIRDAVS QVLKGYDWSL VPMPVRGGGG GTLKAKPHVK RPMNAFMVWA QAARRKLADQ 
YPHLHNAELS KTLGKLWRLL SESEKRPFVE EAERLRVQHK KDHPDYKYQP RRRKSVKTGR 
SDSDSGTELG HHPGGPMYKA DAVLGEAHHH SDHHTGQTHG PPTPPTTPKT DLHQASNGSK 
QELRLEGRRL VDSGRQNIDF SNVDISELSS EVISNMDTFD VHEFDQYLPL NGHSALPTEP 
SQATASGSYG GASYSHSGAT GIGASPVWAH KGAPSASASP TEAGPLRPQI KTEQLSPSHY 
NDQSHGSPGR ADYGSYSAQA SVTTAASATA ASSFASAQCD YTDLQASNYY SPYPGYPPSL 
YQYPYFHSSR RPYASPLLNG LSMPPAHSPS SNWDQPVYTT LTRP

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.