Genular: Defining Cellular Identity and Function

Details for: Serpina1d

Gene ID: 20703

Symbol: Serpina1d

Ensembl ID: ENSMUSG00000071177

Description: serine (or cysteine) peptidase inhibitor, clade A, member 1D

Associated with

Endopeptidase inhibitor activity
(GO:0004866)
Endoplasmic reticulum
(GO:0005783)
Extracellular region
(GO:0005576)
Extracellular space
(GO:0005615)
Golgi apparatus
(GO:0005794)
Identical protein binding
(GO:0042802)
Intracellular membrane-bounded organelle
(GO:0043231)
Negative regulation of endopeptidase activity
(GO:0010951)
Negative regulation of peptidase activity
(GO:0010466)
Peptidase inhibitor activity
(GO:0030414)
Protease binding
(GO:0002020)
Response to chromate
(GO:0046687)
Response to cytokine
(GO:0034097)
Response to lead ion
(GO:0010288)
Response to methanol
(GO:0033986)
Response to peptide hormone
(GO:0043434)
Serine-type endopeptidase inhibitor activity
(GO:0004867)

Other Information

Proteins

Alpha-1-antitrypsin 1-4

Genular Protein ID: 556937391

Symbol: A1AT4_MOUSE

Name: Alpha-1-antitrypsin 1-4

UniProtKB Accession Codes:

Q00897

Database IDs:

Citations:

PubMed ID: 1946354

Title: Multiple murine alpha 1-protease inhibitor genes show unusual evolutionary divergence.

PubMed ID: 1946354

DOI: 10.1073/pnas.88.21.9417

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 8619829

Title: The expression and characterization of five recombinant murine alpha 1-protease inhibitor proteins.

PubMed ID: 8619829

DOI: 10.1006/bbrc.1996.0182

PubMed ID: 11961105

Title: Functional diversification during evolution of the murine alpha(1)-proteinase inhibitor family: role of the hypervariable reactive center loop.

PubMed ID: 11961105

DOI: 10.1093/oxfordjournals.molbev.a004130

PubMed ID: 12659817

Title: A review and comparison of the murine alpha1-antitrypsin and alpha1-antichymotrypsin multigene clusters with the human clade A serpins.

PubMed ID: 12659817

DOI: 10.1016/s0888-7543(02)00041-1

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

Sequence Information:

Length: 413
Mass: 45998
Checksum: D8A90477F371A902
Sequence:

MTPSISWSLL LLAGLCCLVP SFLAEDVQET DTSQKDQSPA SHEIATNLGD FALRLYRELV 
HQSNTSNIFF SPVSIATAFA MLSLGSKGDT HTQILEGLQF NLTQTSEADI HKSFQHLLQT 
LNRPDSELQL STGNGLFVNN DLKLVEKFLE EAKNHYQAEV FSVNFAESEE AKKVINDFVE 
KGTQGKIVEA VKKLDQDTVF ALANYILFKG KWKQPFDPEN TEEAEFHVDE STTVKVPMMT 
LSGMLDVHHC SMLSSWVLLM DYAGNTTAVF LLPDDGKMQH LEQTLNKELI SQFLLNRRRS 
DAQIHIPRLS ISGNYNLKTL MSPLGITRIF NNGADLSGIT EENAPLKLSK AVHKAVLTID 
ETGTEAAAAT VLQVATYSMP PIVRFDHPFL FIIFEEHTQS PIFVGKVVDP THK

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Serpina1d

Associated with

Other Information

Multiple murine alpha 1-protease inhibitor genes show unusual evolutionary divergence. PubMed ID: 1946354

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072

The expression and characterization of five recombinant murine alpha 1-protease inhibitor proteins. PubMed ID: 8619829

Functional diversification during evolution of the murine alpha(1)-proteinase inhibitor family: role of the hypervariable reactive center loop. PubMed ID: 11961105

A review and comparison of the murine alpha1-antitrypsin and alpha1-antichymotrypsin multigene clusters with the human clade A serpins. PubMed ID: 12659817