Genular: Defining Cellular Identity and Function

Details for: Serpina1e

Gene ID: 20704

Symbol: Serpina1e

Ensembl ID: ENSMUSG00000072849

Description: serine (or cysteine) peptidase inhibitor, clade A, member 1E

Associated with

Endopeptidase inhibitor activity
(GO:0004866)
Endoplasmic reticulum
(GO:0005783)
Extracellular region
(GO:0005576)
Extracellular space
(GO:0005615)
Golgi apparatus
(GO:0005794)
Identical protein binding
(GO:0042802)
Intracellular membrane-bounded organelle
(GO:0043231)
Negative regulation of endopeptidase activity
(GO:0010951)
Negative regulation of peptidase activity
(GO:0010466)
Peptidase inhibitor activity
(GO:0030414)
Protease binding
(GO:0002020)
Response to chromate
(GO:0046687)
Response to cytokine
(GO:0034097)
Response to lead ion
(GO:0010288)
Response to methanol
(GO:0033986)
Response to peptide hormone
(GO:0043434)
Serine-type endopeptidase inhibitor activity
(GO:0004867)

Other Information

Proteins

Alpha-1-antitrypsin 1-5

Genular Protein ID: 2264142860

Symbol: A1AT5_MOUSE

Name: Alpha-1-antitrypsin 1-5

UniProtKB Accession Codes:

Q00898 Q3UJ83 Q545P1

Database IDs:

Citations:

PubMed ID: 1946354

Title: Multiple murine alpha 1-protease inhibitor genes show unusual evolutionary divergence.

PubMed ID: 1946354

DOI: 10.1073/pnas.88.21.9417

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 8619829

Title: The expression and characterization of five recombinant murine alpha 1-protease inhibitor proteins.

PubMed ID: 8619829

DOI: 10.1006/bbrc.1996.0182

PubMed ID: 12659817

Title: A review and comparison of the murine alpha1-antitrypsin and alpha1-antichymotrypsin multigene clusters with the human clade A serpins.

PubMed ID: 12659817

DOI: 10.1016/s0888-7543(02)00041-1

PubMed ID: 16944957

Title: Proteome-wide characterization of N-glycosylation events by diagonal chromatography.

PubMed ID: 16944957

DOI: 10.1021/pr060186m

Sequence Information:

Length: 413
Mass: 45891
Checksum: 42331F107CA06C55
Sequence:

MTPSISWCLL LLAGLCCLVP SFLAEDVQET DTSQKDQSPA SHEIATNLGD FAISLYRELV 
HQSNTSNIFF SPVSIATAFA MLSLGSKGDT HTQILEGLQF NLTQTSEADI HNSFQHLLQT 
LNRPDSELQL STGNGLFVNN DLKLVEKFLE EAKNHYQAEV FSVNFAESEE AKKVINDFVE 
KGTQGKIVEA VKKLEQDTVF VLANYILFKG KWKKPFDPEN TKQAEFHVDE STTVKVPMMT 
LSGMLDVHHC STLSSWVLLM DYAGNATAVF LLPDDGKMQH LEQTLNKELI SKFLLNRRRR 
LAQIHIPRLS ISGNYNLETL MSPLGITRIF NSGADLSGIT EENAPLKLSQ AVHKAVLTID 
ETGTEAAAAT VLQGGFLSMP PILHFNRPFL FIIFEEHSQS PLFVGKVVDP THK

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Serpina1e

Associated with

Other Information

Multiple murine alpha 1-protease inhibitor genes show unusual evolutionary divergence. PubMed ID: 1946354

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

The expression and characterization of five recombinant murine alpha 1-protease inhibitor proteins. PubMed ID: 8619829

A review and comparison of the murine alpha1-antitrypsin and alpha1-antichymotrypsin multigene clusters with the human clade A serpins. PubMed ID: 12659817