Genular: Defining Cellular Identity and Function

Details for: Serpine2

Gene ID: 20720

Symbol: Serpine2

Ensembl ID: ENSMUSG00000026249

Description: serine (or cysteine) peptidase inhibitor, clade E, member 2

Associated with

Common pathway of fibrin clot formation
(R-MMU-140875)
Dissolution of fibrin clot
(R-MMU-75205)
Formation of fibrin clot (clotting cascade)
(R-MMU-140877)
Hemostasis
(R-MMU-109582)
Intrinsic pathway of fibrin clot formation
(R-MMU-140837)
Blood coagulation
(GO:0007596)
Cell differentiation
(GO:0030154)
Cerebellar granular layer morphogenesis
(GO:0021683)
Collagen-containing extracellular matrix
(GO:0062023)
Cytosol
(GO:0005829)
Dense core granule biogenesis
(GO:0061110)
Detection of mechanical stimulus involved in sensory perception
(GO:0050974)
Extracellular region
(GO:0005576)
Extracellular space
(GO:0005615)
Glycosaminoglycan binding
(GO:0005539)
Heparin binding
(GO:0008201)
Innervation
(GO:0060384)
Long-term synaptic potentiation
(GO:0060291)
Mating plug formation
(GO:0042628)
Multicellular organism development
(GO:0007275)
Negative regulation of blood coagulation
(GO:0030195)
Negative regulation of cell growth
(GO:0030308)
Negative regulation of cell population proliferation
(GO:0008285)
Negative regulation of endopeptidase activity
(GO:0010951)
Negative regulation of peptidase activity
(GO:0010466)
Negative regulation of phosphatidylinositol 3-kinase/protein kinase b signal transduction
(GO:0051898)
Negative regulation of plasminogen activation
(GO:0010757)
Negative regulation of platelet activation
(GO:0010544)
Negative regulation of platelet aggregation
(GO:0090331)
Negative regulation of protein catabolic process
(GO:0042177)
Negative regulation of protein processing
(GO:0010955)
Negative regulation of proteolysis
(GO:0045861)
Negative regulation of smoothened signaling pathway
(GO:0045879)
Negative regulation of sodium ion transport
(GO:0010766)
Nervous system development
(GO:0007399)
Neuromuscular junction
(GO:0031594)
Neuronal cell body
(GO:0043025)
Peptidase inhibitor activity
(GO:0030414)
Platelet activation
(GO:0030168)
Platelet alpha granule
(GO:0031091)
Positive regulation of astrocyte differentiation
(GO:0048711)
Positive regulation of neuron projection development
(GO:0010976)
Protein catabolic process
(GO:0030163)
Regulation of synaptic transmission, glutamatergic
(GO:0051966)
Regulation of timing of cell differentiation
(GO:0048505)
Response to wounding
(GO:0009611)
Secretion by cell
(GO:0032940)
Secretory granule organization
(GO:0033363)
Seminal vesicle epithelium development
(GO:0061108)
Serine-type endopeptidase inhibitor activity
(GO:0004867)
Signaling receptor binding
(GO:0005102)

Other Information

Proteins

Glia-derived nexin

Genular Protein ID: 743889571

Symbol: GDN_MOUSE

Name: Glia-derived nexin

UniProtKB Accession Codes:

Q07235 Q921T7

Database IDs:

Citations:

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 8491179

Title: Protease-nexin I as an androgen-dependent secretory product of the murine seminal vesicle.

PubMed ID: 8491179

DOI: 10.1002/j.1460-2075.1993.tb05835.x

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

Sequence Information:

Length: 397
Mass: 44207
Checksum: B8EBAE3CA899D4A5
Sequence:

MNWHFPFFIL TTVTLYSVHS QFNSLSLEEL GSNTGIQVFN QIIKSRPHEN VVVSPHGIAS 
ILGMLQLGAD GKTKKQLSTV MRYNVNGVGK VLKKINKAIV SKKNKDIVTV ANAVFLRNGF 
KMEVPFAVRN KDVFQCEVQN VNFQDPASAS ESINFWVKNE TRGMIDNLLS PNLIDGALTR 
LVLVNAVYFK GLWKSRFQPE STKKRTFVAG DGKSYQVPML AQLSVFRSGS TRTPNGLWYN 
FIELPYHGES ISMLIALPTE SSTPLSAIIP HITTKTIDSW MNTMVPKRMQ LVLPKFTAVA 
QTDLKEPLKA LGITEMFEPS KANFTKITRS ESLHVSHILQ KAKIEVSEDG TKASAATTAI 
LIARSSPPWF IVDRPFLFSI RHNPTGAILF LGQVNKP

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.