Details for: Spic

Gene ID: 20728

Symbol: Spic

Ensembl ID: ENSMUSG00000004359

Description: Spi-C transcription factor (Spi-1/PU.1 related)

Associated with

  • Blastocyst development
    (GO:0001824)
  • Cell differentiation
    (GO:0030154)
  • Dna-binding transcription activator activity, rna polymerase ii-specific
    (GO:0001228)
  • Dna-binding transcription factor activity
    (GO:0003700)
  • Dna-binding transcription factor activity, rna polymerase ii-specific
    (GO:0000981)
  • Dna binding
    (GO:0003677)
  • Nucleus
    (GO:0005634)
  • Positive regulation of transcription by rna polymerase ii
    (GO:0045944)
  • Regulation of dna-templated transcription
    (GO:0006355)
  • Regulation of transcription by rna polymerase ii
    (GO:0006357)
  • Rna polymerase ii cis-regulatory region sequence-specific dna binding
    (GO:0000978)
  • Sequence-specific dna binding
    (GO:0043565)

Other Information

Genular Protein ID: 1681722429

Symbol: SPIC_MOUSE

Name: Transcription factor Spi-C

UniProtKB Accession Codes:

Q6P3D7 Q3U064 Q3U0G6 Q3U1E9 Q9Z0Y0

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CCDS 1 CTD 1 DNASU 1 EMBL 7 Ensembl 1 ExpressionAtlas 1 GO 7 Gene3D 1 GeneTree 1 Genevisible 1 GlyGen 1 HOGENOM 1 InParanoid 1 InterPro 4 KEGG 1 MGI 1 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 PRINTS 1 PRO 1 PROSITE 2 PROSITE-ProRule 1 PaxDb 1 Pfam 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 2 RNAct 1 RefSeq 1 SMART 1 SMR 1 STRING 1 SUPFAM 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1

Citations:

PubMed ID: 10187812

Title: Spi-C, a novel Ets protein that is temporally regulated during B lymphocyte development.

PubMed ID: 10187812

DOI: 10.1074/jbc.274.15.10259

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 10464163

Title: Prf, a novel Ets family protein that binds to the PU.1 binding motif, is specifically expressed in restricted stages of B cell development.

PubMed ID: 10464163

DOI: 10.1093/intimm/11.9.1423

PubMed ID: 19037245

Title: Role for Spi-C in the development of red pulp macrophages and splenic iron homeostasis.

PubMed ID: 19037245

DOI: 10.1038/nature07472

Sequence Information:

  • Length: 242
  • Mass: 27942
  • Checksum: F4F77B59CC0F7F3C
  • Sequence:
    • MTCCIDQDSL GQTFQDAIDI LIQQSAGESQ YSSENRNYMA IINPYPHVRG NANYYGMSPT 
ENPLYDWRGV TNGSADLYLE GGFHQSVQNI AESQLVQPPF FQQKGGRGRR KLRLFEYLFE 
SLCNSEMVSC IQWVDKARGI FQFISKNKET LAELWGQRKG NRKPMTYQKM ARALRNYART 
GEIIKIRRKL TYQFSEAVLQ RLAPANYLGK DLFYPQYGQP DQGYLSLNHW NANHYAHGSY 
QS

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.