Details for: Spn

Gene ID: 20737

Symbol: Spn

Ensembl ID: ENSMUSG00000051457

Description: sialophorin

Associated with

Other Information

Genular Protein ID: 776880049

Symbol: LEUK_MOUSE

Name: Leukosialin

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 2347365

Title: Protein sequence and gene structure for mouse leukosialin (CD43), a T lymphocyte mucin without introns in the coding sequence.

PubMed ID: 2347365

DOI: 10.1002/eji.1830200424

PubMed ID: 2144340

Title: The nucleotide sequence of Ly 48 (mouse leukosialin, sialophorin): the mouse homolog of CD43.

PubMed ID: 2144340

DOI: 10.1093/nar/18.16.4932

PubMed ID: 7514104

Title: A unique murine CD43 epitope Lp-3: distinct distribution from another CD43 epitope S7.

PubMed ID: 7514104

DOI: 10.1006/cimm.1994.1133

PubMed ID: 1973410

Title: cDNA cloning and localization of the mouse leukosialin gene (Ly48) to chromosome 7.

PubMed ID: 1973410

DOI: 10.1007/bf02115004

PubMed ID: 11078605

Title: Identification and cloning of a CD43-associated serine/threonine kinase.

PubMed ID: 11078605

DOI: 10.1006/cimm.2000.1716

PubMed ID: 11238599

Title: CD43 functions as a T cell counterreceptor for the macrophage adhesion receptor sialoadhesin (Siglec-1).

PubMed ID: 11238599

DOI: 10.4049/jimmunol.166.6.3637

PubMed ID: 11728336

Title: ERM-dependent movement of CD43 defines a novel protein complex distal to the immunological synapse.

PubMed ID: 11728336

DOI: 10.1016/s1074-7613(01)00224-2

PubMed ID: 17638845

Title: Signaling through CD43 regulates CD4 T-cell trafficking.

PubMed ID: 17638845

DOI: 10.1182/blood-2007-01-065276

PubMed ID: 18490738

Title: CD43 regulates Th2 differentiation and inflammation.

PubMed ID: 18490738

DOI: 10.4049/jimmunol.180.11.7385

PubMed ID: 19696198

Title: CD43 processing and nuclear translocation of CD43 cytoplasmic tail are required for cell homeostasis.

PubMed ID: 19696198

DOI: 10.1182/blood-2009-06-228791

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 21289089

Title: CD43 interaction with ezrin-radixin-moesin (ERM) proteins regulates T-cell trafficking and CD43 phosphorylation.

PubMed ID: 21289089

DOI: 10.1091/mbc.e10-07-0586

PubMed ID: 26700769

Title: CD43 functions as an E-selectin ligand for Th17 cells in vitro and is required for rolling on the vascular endothelium and Th17 cell recruitment during inflammation in vivo.

PubMed ID: 26700769

DOI: 10.4049/jimmunol.1501171

PubMed ID: 18614175

Title: Structural basis of the cytoplasmic tail of adhesion molecule CD43 and its binding to ERM proteins.

PubMed ID: 18614175

DOI: 10.1016/j.jmb.2008.05.085

Sequence Information:

  • Length: 395
  • Mass: 40038
  • Checksum: 369F201B04DBC055
  • Sequence:
  • MALHLLLLFG ACWVQVASPD SLQRTTMLPS TPHITAPSTS EAQNASPSVS VGSGTVDSKE 
    TISPWGQTTI PVSLTPLETT ELSSLETSAG ASMSTPVPEP TASQEVSSKT SALLPEPSNV 
    ASDPPVTAAN PVTDGPAANP VTDGTAASTS ISKGTSAPPT TVTTSSNETS GPSVATTVSS 
    KTSGPPVTTA TGSLGPSSEM HGLPATTATS SVESSSVARG TSVSSRKTST TSTQDPITTR 
    SPSQESSGML LVPMLIALVV VLALVALLLL WRQRQKRRTG ALTLSGGGKR NGVVDAWAGP 
    ARVPDEEATT TSGAGGNKGS EVLETEGSGQ RPTLTTFFSR RKSRQGSLVL EELKPGSGPN 
    LKGEEEPLVG SEDEAVETPT SDGPQAKDEA APQSL

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.