Genular: Defining Cellular Identity and Function

Details for: Sqle

Gene ID: 20775

Symbol: Sqle

Ensembl ID: ENSMUSG00000022351

Description: squalene epoxidase

Associated with

Cholesterol biosynthesis
(R-MMU-191273)
Metabolism
(R-MMU-1430728)
Metabolism of lipids
(R-MMU-556833)
Metabolism of steroids
(R-MMU-8957322)
Cholesterol metabolic process
(GO:0008203)
Endoplasmic reticulum
(GO:0005783)
Fad binding
(GO:0071949)
Flavin adenine dinucleotide binding
(GO:0050660)
Intracellular membrane-bounded organelle
(GO:0043231)
Lipid droplet formation
(GO:0140042)
Lipid metabolic process
(GO:0006629)
Membrane
(GO:0016020)
Oxidoreductase activity
(GO:0016491)
Regulation of cell population proliferation
(GO:0042127)
Response to organic substance
(GO:0010033)
Squalene monooxygenase activity
(GO:0004506)
Sterol biosynthetic process
(GO:0016126)

Other Information

Proteins

Squalene monooxygenase

Genular Protein ID: 3034521261

Symbol: ERG1_MOUSE

Name: Squalene monooxygenase

UniProtKB Accession Codes:

P52019

Database IDs:

Citations:

PubMed ID: 7873613

Title: Nucleotide sequence of a cDNA for mouse squalene epoxidase.

PubMed ID: 7873613

DOI: 10.1016/0167-4781(94)00245-x

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

Sequence Information:

Length: 572
Mass: 63770
Checksum: 5C30D80A204664D4
Sequence:

MWTFLGIATF TYFYKKCGDV TLANKELLLC VLVFLSLGLV LSYRCRHRHG GLLGRHQSGA 
QFAAFSDILS ALPLIGFFWA KSPESEKKEQ LESKKCRKEI GLSETTLTGA ATSVSTSFVT 
DPEVIIVGSG VLGSALAAVL SRDGRKVTVI ERDLKEPDRI VGELLQPGGY RVLQELGLGD 
TVEGLNAHHI HGYIVHDYES RSEVQIPYPL SETNQVQSGI AFHHGRFIMS LRKAAMAEPN 
VKFIEGVVLQ LLEEDDAVIG VQYKDKETGD TKELHAPLTV VADGLFSKFR KSLISSKVSV 
SSHFVGFLMK DAPQFKPNFA ELVLVNPSPV LIYQISSSET RVLVDIRGEL PRNLREYMAE 
QIYPQLPEHL KESFLEASQN GRLRTMPASF LPPSSVNKRG VLILGDAYNL RHPLTGGGMT 
VALKDIKLWR QLLKDIPDLY DDAAIFQAKK SFFWSRKRTH SFVVNVLAQA LYELFSATDD 
SLHQLRKACF LYFKLGGECV TGPVGLLSIL SPHPLVLIRH FFSVAIYATY FCFKSEPWAT 
KPRALFSSGA VLYKACSILF PLIYSEMKYL VH

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.