Details for: Src

Gene ID: 20779

Symbol: Src

Ensembl ID: ENSMUSG00000027646

Description: Rous sarcoma oncogene

Associated with

Other Information

Genular Protein ID: 1752310702

Symbol: SRC_MOUSE

Name: Proto-oncogene c-Src

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 2440106

Title: Neuronal pp60c-src contains a six-amino acid insertion relative to its non-neuronal counterpart.

PubMed ID: 2440106

DOI: 10.1126/science.2440106

PubMed ID: 19468303

Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.

PubMed ID: 19468303

DOI: 10.1371/journal.pbio.1000112

PubMed ID: 7681396

Title: Activation of Src family kinases by colony stimulating factor-1, and their association with its receptor.

PubMed ID: 7681396

DOI: 10.1002/j.1460-2075.1993.tb05735.x

PubMed ID: 7542762

Title: Direct and specific interaction of c-Src with Neu is involved in signaling by the epidermal growth factor receptor.

PubMed ID: 7542762

PubMed ID: 8641341

Title: Activation of Src-family protein tyrosine kinases and phosphatidylinositol 3-kinase in 3T3-L1 mouse preadipocytes by interleukin-11.

PubMed ID: 8641341

PubMed ID: 8910389

Title: Bombesin, bradykinin, vasopressin, and phorbol esters rapidly and transiently activate Src family tyrosine kinases in Swiss 3T3 cells. Dissociation from tyrosine phosphorylation of p125 focal adhesion kinase.

PubMed ID: 8910389

DOI: 10.1074/jbc.271.44.27895

PubMed ID: 9344858

Title: c-Src activates both STAT1 and STAT3 in PDGF-stimulated NIH3T3 cells.

PubMed ID: 9344858

DOI: 10.1006/bbrc.1997.7493

PubMed ID: 9819391

Title: ASAP1, a phospholipid-dependent arf GTPase-activating protein that associates with and is phosphorylated by Src.

PubMed ID: 9819391

DOI: 10.1128/mcb.18.12.7038

PubMed ID: 11433297

Title: N-CAM modulates tumour-cell adhesion to matrix by inducing FGF-receptor signalling.

PubMed ID: 11433297

DOI: 10.1038/35083041

PubMed ID: 14644164

Title: The role of c-Src in platelet-derived growth factor alpha receptor internalization.

PubMed ID: 14644164

DOI: 10.1016/j.yexcr.2003.08.001

PubMed ID: 12615910

Title: Regulation of cytochrome c oxidase activity by c-Src in osteoclasts.

PubMed ID: 12615910

DOI: 10.1083/jcb.200209098

PubMed ID: 12925710

Title: EphB1 recruits c-Src and p52Shc to activate MAPK/ERK and promote chemotaxis.

PubMed ID: 12925710

DOI: 10.1083/jcb.200302073

PubMed ID: 14739300

Title: Src kinase activity is essential for osteoclast function.

PubMed ID: 14739300

DOI: 10.1074/jbc.m311032200

PubMed ID: 16684964

Title: Identification of Y589 and Y599 in the juxtamembrane domain of Flt3 as ligand-induced autophosphorylation sites involved in binding of Src family kinases and the protein tyrosine phosphatase SHP2.

PubMed ID: 16684964

DOI: 10.1182/blood-2005-07-008896

PubMed ID: 17000758

Title: Ccpg1, a novel scaffold protein that regulates the activity of the Rho guanine nucleotide exchange factor Dbs.

PubMed ID: 17000758

DOI: 10.1128/mcb.00670-06

PubMed ID: 18034455

Title: Large-scale identification and evolution indexing of tyrosine phosphorylation sites from murine brain.

PubMed ID: 18034455

DOI: 10.1021/pr0701254

PubMed ID: 19144319

Title: The phagosomal proteome in interferon-gamma-activated macrophages.

PubMed ID: 19144319

DOI: 10.1016/j.immuni.2008.11.006

PubMed ID: 19122674

Title: Deficiency of a beta-arrestin-2 signal complex contributes to insulin resistance.

PubMed ID: 19122674

DOI: 10.1038/nature07617

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 20093046

Title: Collagen stimulates discoidin domain receptor 1-mediated migration of smooth muscle cells through Src.

PubMed ID: 20093046

DOI: 10.1016/j.carpath.2009.12.006

PubMed ID: 21525037

Title: The guanine nucleotide exchange factor Arhgef5 plays crucial roles in Src-induced podosome formation.

PubMed ID: 21525037

DOI: 10.1242/jcs.080291

PubMed ID: 22801373

Title: Protein tyrosine phosphatase alpha phosphotyrosyl-789 binds BCAR3 to position Cas for activation at integrin-mediated focal adhesions.

PubMed ID: 22801373

DOI: 10.1128/mcb.00214-12

PubMed ID: 31320558

Title: Nuclear hnRNPA2B1 initiates and amplifies the innate immune response to DNA viruses.

PubMed ID: 31320558

DOI: 10.1126/science.aav0758

PubMed ID: 8672527

Title: Regulation, substrates and functions of src.

PubMed ID: 8672527

DOI: 10.1016/0304-419x(96)00003-0

PubMed ID: 9442882

Title: Cellular functions regulated by Src family kinases.

PubMed ID: 9442882

DOI: 10.1146/annurev.cellbio.13.1.513

PubMed ID: 11964124

Title: Novel regulation and function of Src tyrosine kinase.

PubMed ID: 11964124

DOI: 10.1007/s00018-002-8438-2

PubMed ID: 25731159

Title: A gp130-Src-YAP module links inflammation to epithelial regeneration.

PubMed ID: 25731159

DOI: 10.1038/nature14228

PubMed ID: 28362576

Title: Ambra1 spatially regulates Src activity and Src/FAK-mediated cancer cell invasion via trafficking networks.

PubMed ID: 28362576

DOI: 10.7554/elife.23172

Sequence Information:

  • Length: 535
  • Mass: 59891
  • Checksum: 22CB5C6BE7A061C0
  • Sequence:
  • MGSNKSKPKD ASQRRRSLEP SENVHGAGGA FPASQTPSKP ASADGHRGPS AAFVPPAAEP 
    KLFGGFNSSD TVTSPQRAGP LAGGVTTFVA LYDYESRTET DLSFKKGERL QIVNNTEGDW 
    WLAHSLSTGQ TGYIPSNYVA PSDSIQAEEW YFGKITRRES ERLLLNAENP RGTFLVRESE 
    TTKGAYCLSV SDFDNAKGLN VKHYKIRKLD SGGFYITSRT QFNSLQQLVA YYSKHADGLC 
    HRLTTVCPTS KPQTQGLAKD AWEIPRESLR LEVKLGQGCF GEVWMGTWNG TTRVAIKTLK 
    PGTMSPEAFL QEAQVMKKLR HEKLVQLYAV VSEEPIYIVT EYMNKGSLLD FLKGETGKYL 
    RLPQLVDMSA QIASGMAYVE RMNYVHRDLR AANILVGENL VCKVADFGLA RLIEDNEYTA 
    RQGAKFPIKW TAPEAALYGR FTIKSDVWSF GILLTELTTK GRVPYPGMVN REVLDQVERG 
    YRMPCPPECP ESLHDLMCQC WRKEPEERPT FEYLQAFLED YFTSTEPQYQ PGENL

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.