Genular: Defining Cellular Identity and Function

Details for: Stam

Gene ID: 20844

Symbol: Stam

Ensembl ID: ENSMUSG00000026718

Description: signal transducing adaptor molecule (SH3 domain and ITAM motif) 1

Associated with

Cargo recognition for clathrin-mediated endocytosis
(R-MMU-8856825)
Clathrin-mediated endocytosis
(R-MMU-8856828)
Deubiquitination
(R-MMU-5688426)
Egfr downregulation
(R-MMU-182971)
Endosomal sorting complex required for transport (escrt)
(R-MMU-917729)
Membrane trafficking
(R-MMU-199991)
Metabolism of proteins
(R-MMU-392499)
Metalloprotease dubs
(R-MMU-5689901)
Negative regulation of met activity
(R-MMU-6807004)
Post-translational protein modification
(R-MMU-597592)
Rho gtpase cycle
(R-MMU-9012999)
Rhou gtpase cycle
(R-MMU-9013420)
Signaling by egfr
(R-MMU-177929)
Signaling by met
(R-MMU-6806834)
Signaling by receptor tyrosine kinases
(R-MMU-9006934)
Signaling by rho gtpases
(R-MMU-194315)
Signaling by rho gtpases, miro gtpases and rhobtb3
(R-MMU-9716542)
Signal transduction
(R-MMU-162582)
Vesicle-mediated transport
(R-MMU-5653656)
Cytoplasm
(GO:0005737)
Cytosol
(GO:0005829)
Endosome
(GO:0005768)
Escrt-0 complex
(GO:0033565)
Intracellular membrane-bounded organelle
(GO:0043231)
Membrane
(GO:0016020)
Phosphatidylinositol binding
(GO:0035091)
Positive regulation of exosomal secretion
(GO:1903543)
Protein binding
(GO:0005515)
Protein transport
(GO:0015031)
Protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway
(GO:0043328)
Regulation of extracellular exosome assembly
(GO:1903551)
Ubiquitin-like protein ligase binding
(GO:0044389)
Ubiquitin binding
(GO:0043130)

Other Information

Proteins

Signal transducing adapter molecule 1

Genular Protein ID: 259349440

Symbol: STAM1_MOUSE

Name: Signal transducing adapter molecule 1

UniProtKB Accession Codes:

P70297

Database IDs:

Citations:

PubMed ID: 8780729

Title: Cloning of a novel signal-transducing adaptor molecule containing an SH3 domain and ITAM.

PubMed ID: 8780729

DOI: 10.1006/bbrc.1996.1290

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 11340172

Title: Loss of hippocampal CA3 pyramidal neurons in mice lacking STAM1.

PubMed ID: 11340172

DOI: 10.1128/mcb.21.11.3807-3819.2001

PubMed ID: 12446783

Title: Signal-transducing adaptor molecules STAM1 and STAM2 are required for T-cell development and survival.

PubMed ID: 12446783

DOI: 10.1128/mcb.22.24.8648-8658.2002

PubMed ID: 19278655

Title: Hybrid structural model of the complete human ESCRT-0 complex.

PubMed ID: 19278655

DOI: 10.1016/j.str.2009.01.012

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

Sequence Information:

Length: 548
Mass: 59771
Checksum: 1149D4F9F540C8B8
Sequence:

MPLFATNPFD QDVEKATSEL NTAEDWGLIL DICDKVGQSR TGPKDCLRSI MRRVNHKDPH 
VAMQALTLLG ACVSNCGKIF HLEVCSRDFA SEVSNVLNKG HPKVCEKLKA LMVEWTDEFK 
NDPQLSLISA MIKNLKEQGV TFPAIGSQAA EQAKASPALV AKDPGTVATK KEEEDLAKAI 
ELSLKEQRQQ SAPVSTLYPS TSNLLTNHQH EGRKVRAVYD FEAAEDNELT FKAGEIITVL 
DDSDPNWWKG ETHQGVGLFP SNFVTADLTA EPEMIKTEKK TVQFNDDVQI ETIEPEPEPA 
FIDEDKMDQL LQMLQSTDPS DNQPDLPELL HLEAMCHQMG PLIDEKLEDI DRKHSELSEL 
NVKVMEALSL YTKLMNEDPM YSMYAKLQSQ QYYLQSSAVS ASQVYPGPAQ SGTYLVAGSA 
QMTHLQSYSL PPEQLSSISQ GAVPSSANQA LPSQQTQASY PNAMVSSVQG NSYPSQASIY 
SPPAAAAAAA AAAVVPVPVP ADVTIYQNAG PTMSQVPNYT LTSSTLPQTG GSQQPPQPQQ 
AYSQKALL

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Stam

Associated with

Other Information

Cloning of a novel signal-transducing adaptor molecule containing an SH3 domain and ITAM. PubMed ID: 8780729

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Loss of hippocampal CA3 pyramidal neurons in mice lacking STAM1. PubMed ID: 11340172

Signal-transducing adaptor molecules STAM1 and STAM2 are required for T-cell development and survival. PubMed ID: 12446783

Hybrid structural model of the complete human ESCRT-0 complex. PubMed ID: 19278655