Genular: Defining Cellular Identity and Function

Details for: Star

Gene ID: 20845

Symbol: Star

Ensembl ID: ENSMUSG00000031574

Description: steroidogenic acute regulatory protein

Associated with

Metabolism
(R-MMU-1430728)
Metabolism of lipids
(R-MMU-556833)
Metabolism of proteins
(R-MMU-392499)
Metabolism of steroid hormones
(R-MMU-196071)
Metabolism of steroids
(R-MMU-8957322)
Mitochondrial protein degradation
(R-MMU-9837999)
Pregnenolone biosynthesis
(R-MMU-196108)
Bile acid biosynthetic process
(GO:0006699)
Cellular lipid metabolic process
(GO:0044255)
Cellular response to interferon-alpha
(GO:0035457)
Cholesterol binding
(GO:0015485)
Cholesterol transfer activity
(GO:0120020)
Estrogen biosynthetic process
(GO:0006703)
Glucocorticoid metabolic process
(GO:0008211)
Intracellular cholesterol transport
(GO:0032367)
Lipid binding
(GO:0008289)
Lipid transport
(GO:0006869)
Mitochondrial crista
(GO:0030061)
Mitochondrion
(GO:0005739)
Negative regulation of neuron apoptotic process
(GO:0043524)
Neuronal cell body
(GO:0043025)
Positive regulation of bile acid biosynthetic process
(GO:0070859)
Positive regulation of gene expression
(GO:0010628)
Positive regulation of neurogenesis
(GO:0050769)
Regulation of neuronal synaptic plasticity
(GO:0048168)
Regulation of steroid biosynthetic process
(GO:0050810)
Steroid biosynthetic process
(GO:0006694)

Other Information

Proteins

Steroidogenic acute regulatory protein, mitochondrial

Genular Protein ID: 600138701

Symbol: STAR_MOUSE

Name: Steroidogenic acute regulatory protein, mitochondrial

UniProtKB Accession Codes:

P51557 Q543A5 Q924Y5 Q9D2G1

Database IDs:

Citations:

PubMed ID: 7961770

Title: The purification, cloning, and expression of a novel luteinizing hormone-induced mitochondrial protein in MA-10 mouse Leydig tumor cells. Characterization of the steroidogenic acute regulatory protein (StAR).

PubMed ID: 7961770

DOI: 10.1016/s0021-9258(18)46930-x

PubMed ID: 12486153

Title: An essential component in steroid synthesis, the steroidogenic acute regulatory protein, is expressed in discrete regions of the brain.

PubMed ID: 12486153

DOI: 10.1523/jneurosci.22-24-10613.2002

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 1797581

Title: Acute action of luteinizing hormone on mouse Leydig cells: accumulation of mitochondrial phosphoproteins and stimulation of testosterone synthesis.

PubMed ID: 1797581

DOI: 10.1016/0303-7207(91)90210-j

PubMed ID: 7588255

Title: Steroid production after in vitro transcription, translation, and mitochondrial processing of protein products of complementary deoxyribonucleic acid for steroidogenic acute regulatory protein.

PubMed ID: 7588255

DOI: 10.1210/endo.136.11.7588255

Sequence Information:

Length: 284
Mass: 31626
Checksum: 9BB13E52D4439B72
Sequence:

MFLATFKLCA GSSYRHMRNM KGLRHQAVLA IGQELNWRAL GDSSPGWMGQ VRRRSSLLGS 
QLEATLYSDQ ELSYIQQGEV AMQKALGILN NQEGWKKESQ QENGDEVLSK MVPDVGKVFR 
LEVVVDQPMD RLYEELVDRM EAMGEWNPNV KEIKVLQRIG KDTVITHELA AAAAGNLVGP 
RDFVSVRCTK RRGSTCVLAG MATHFGEMPE QSGVIRAEHG PTCMVLHPLA GSPSKTKLTW 
LLSIDLKGWL PKTIINQVLS QTQIEFANHL RKRLEASPAS EAQC

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Star

Associated with

Other Information

The purification, cloning, and expression of a novel luteinizing hormone-induced mitochondrial protein in MA-10 mouse Leydig tumor cells. Characterization of the steroidogenic acute regulatory protein (StAR). PubMed ID: 7961770

An essential component in steroid synthesis, the steroidogenic acute regulatory protein, is expressed in discrete regions of the brain. PubMed ID: 12486153

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Acute action of luteinizing hormone on mouse Leydig cells: accumulation of mitochondrial phosphoproteins and stimulation of testosterone synthesis. PubMed ID: 1797581