Genular: Defining Cellular Identity and Function

Details for: Bhlhe40

Gene ID: 20893

Symbol: Bhlhe40

Ensembl ID: ENSMUSG00000030103

Description: basic helix-loop-helix family, member e40

Associated with

Anterior/posterior pattern specification
(GO:0009952)
Bhlh transcription factor binding
(GO:0043425)
Circadian regulation of gene expression
(GO:0032922)
Circadian rhythm
(GO:0007623)
Cytoplasm
(GO:0005737)
Dna-binding transcription factor activity, rna polymerase ii-specific
(GO:0000981)
Dna-binding transcription repressor activity, rna polymerase ii-specific
(GO:0001227)
Dna binding
(GO:0003677)
E-box binding
(GO:0070888)
Entrainment of circadian clock by photoperiod
(GO:0043153)
Mrf binding
(GO:0043426)
Negative regulation of dna-binding transcription factor activity
(GO:0043433)
Negative regulation of dna-templated transcription
(GO:0045892)
Negative regulation of transcription by rna polymerase ii
(GO:0000122)
Nuclear body
(GO:0016604)
Nucleoplasm
(GO:0005654)
Nucleus
(GO:0005634)
Protein binding
(GO:0005515)
Protein dimerization activity
(GO:0046983)
Protein domain specific binding
(GO:0019904)
Protein heterodimerization activity
(GO:0046982)
Protein homodimerization activity
(GO:0042803)
Regulation of circadian rhythm
(GO:0042752)
Regulation of dna-templated transcription
(GO:0006355)
Regulation of neurogenesis
(GO:0050767)
Regulation of transcription by rna polymerase ii
(GO:0006357)
Response to light stimulus
(GO:0009416)
Rhythmic process
(GO:0048511)
Rna polymerase ii-specific dna-binding transcription factor binding
(GO:0061629)
Rna polymerase ii cis-regulatory region sequence-specific dna binding
(GO:0000978)
Sequence-specific double-stranded dna binding
(GO:1990837)

Other Information

Proteins

Class E basic helix-loop-helix protein 40

Genular Protein ID: 2039895636

Symbol: BHE40_MOUSE

Name: Class E basic helix-loop-helix protein 40

UniProtKB Accession Codes:

O35185 P97289

Database IDs:

Citations:

PubMed ID: 9284045

Title: Overexpression of Stra13, a novel retinoic acid-inducible gene of the basic helix-loop-helix family, inhibits mesodermal and promotes neuronal differentiation of P19 cells.

PubMed ID: 9284045

DOI: 10.1101/gad.11.16.2052

PubMed ID: 9050988

Title: Identification of interaction partners for the basic-helix-loop-helix protein E47.

PubMed ID: 9050988

DOI: 10.1038/sj.onc.1200912

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 14672706

Title: A novel autofeedback loop of Dec1 transcription involved in circadian rhythm regulation.

PubMed ID: 14672706

DOI: 10.1016/j.bbrc.2003.11.099

PubMed ID: 15560782

Title: Functional analysis of the basic helix-loop-helix transcription factor DEC1 in circadian regulation. Interaction with BMAL1.

PubMed ID: 15560782

DOI: 10.1111/j.1432-1033.2004.04379.x

PubMed ID: 18411297

Title: DEC1 modulates the circadian phase of clock gene expression.

PubMed ID: 18411297

DOI: 10.1128/mcb.02168-07

PubMed ID: 19131326

Title: Large scale localization of protein phosphorylation by use of electron capture dissociation mass spectrometry.

PubMed ID: 19131326

DOI: 10.1074/mcp.m800451-mcp200

PubMed ID: 19786558

Title: The basic helix-loop-helix proteins differentiated embryo chondrocyte (DEC) 1 and DEC2 function as corepressors of retinoid X receptors.

PubMed ID: 19786558

DOI: 10.1124/mol.109.057000

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 30012868

Title: Dec1 and CLOCK regulate Na+/K+-ATPase beta1 subunit expression and blood pressure.

PubMed ID: 30012868

DOI: 10.1161/hypertensionaha.118.11075

Sequence Information:

Length: 411
Mass: 45361
Checksum: B392893CD49292BC
Sequence:

MERIPSAQPP PTCLPKAPGL EHGDLSGMDF AHMYQVYKSR RGIKRSEDSK ETYKLPHRLI 
EKKRRDRINE CIAQLKDLLP EHLKLTTLGH LEKAVVLELT LKHVKALTNL IDQQQQKIIA 
LQSGLQAGDL SGRNLEAGQE MFCSGFQTCA REVLQYLAKH ENTRDLKSSQ LVTHLHRVVS 
ELLQGGASRK PLDSAPKAVD LKEKPSFLAK GSEGPGKNCV PVIQRTFAPS GGEQSGSDTD 
TDSGYGGELE KGDLRSEQPY FKSDHGRRFA VGERVSTIKQ ESEEPPTKKS RMQLSEEEGH 
FAGSDLMGSP FLGPHPHQPP FCLPFYLIPP SATAYLPMLE KCWYPTSVPV LYPGLNTSAA 
ALSSFMNPDK IPTPLLLPQR LPSPLAHSSL DSSALLQALK QIPPLNLETK D

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Bhlhe40

Associated with

Other Information

Overexpression of Stra13, a novel retinoic acid-inducible gene of the basic helix-loop-helix family, inhibits mesodermal and promotes neuronal differentiation of P19 cells. PubMed ID: 9284045

Identification of interaction partners for the basic-helix-loop-helix protein E47. PubMed ID: 9050988

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

A novel autofeedback loop of Dec1 transcription involved in circadian rhythm regulation. PubMed ID: 14672706

Functional analysis of the basic helix-loop-helix transcription factor DEC1 in circadian regulation. Interaction with BMAL1. PubMed ID: 15560782

DEC1 modulates the circadian phase of clock gene expression. PubMed ID: 18411297

Large scale localization of protein phosphorylation by use of electron capture dissociation mass spectrometry. PubMed ID: 19131326

The basic helix-loop-helix proteins differentiated embryo chondrocyte (DEC) 1 and DEC2 function as corepressors of retinoid X receptors. PubMed ID: 19786558

A tissue-specific atlas of mouse protein phosphorylation and expression. PubMed ID: 21183079

Dec1 and CLOCK regulate Na+/K+-ATPase beta1 subunit expression and blood pressure. PubMed ID: 30012868