Details for: Stra8

Gene ID: 20899

Symbol: Stra8

Ensembl ID: ENSMUSG00000029848

Description: stimulated by retinoic acid gene 8

Associated with

Other Information

Genular Protein ID: 4155426530

Symbol: STRA8_MOUSE

Name: N/A

UniProtKB Accession Codes:

P70278 Q496Q5

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 CCDS 1 CTD 1 DNASU 1 EMBL 6 Ensembl 2 ExpressionAtlas 1 GO 12 GeneTree 1 Genevisible 1 HOGENOM 1 InParanoid 1 IntAct 1 InterPro 1 KEGG 1 MGI 2 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 PRO 1 PaxDb 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 RNAct 1 RefSeq 2 SAM 1 SMR 1 STRING 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1

Citations:

PubMed ID: 8896602

Title: Characterization of a premeiotic germ cell-specific cytoplasmic protein encoded by Stra8, a novel retinoic acid-responsive gene.

PubMed ID: 8896602

DOI: 10.1083/jcb.135.2.469

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 14550793

Title: Sexual differentiation of germ cells in XX mouse gonads occurs in an anterior-to-posterior wave.

PubMed ID: 14550793

DOI: 10.1016/s0012-1606(03)00391-9

PubMed ID: 17115059

Title: In germ cells of mouse embryonic ovaries, the decision to enter meiosis precedes premeiotic DNA replication.

PubMed ID: 17115059

DOI: 10.1038/ng1919

PubMed ID: 16461896

Title: Retinoic acid regulates sex-specific timing of meiotic initiation in mice.

PubMed ID: 16461896

DOI: 10.1073/pnas.0510813103

PubMed ID: 18322276

Title: Expression of stimulated by retinoic acid gene 8 (Stra8) in spermatogenic cells induced by retinoic acid: an in vivo study in vitamin A-sufficient postnatal murine testes.

PubMed ID: 18322276

DOI: 10.1095/biolreprod.107.066795

PubMed ID: 18799751

Title: Stra8 and its inducer, retinoic acid, regulate meiotic initiation in both spermatogenesis and oogenesis in mice.

PubMed ID: 18799751

DOI: 10.1073/pnas.0807297105

PubMed ID: 18799790

Title: STRA8-deficient spermatocytes initiate, but fail to complete, meiosis and undergo premature chromosome condensation.

PubMed ID: 18799790

DOI: 10.1242/jcs.035071

PubMed ID: 19805549

Title: STRA8 shuttles between nucleus and cytoplasm and displays transcriptional activity.

PubMed ID: 19805549

DOI: 10.1074/jbc.m109.056481

PubMed ID: 20951351

Title: The mammalian doublesex homolog DMRT1 is a transcriptional gatekeeper that controls the mitosis versus meiosis decision in male germ cells.

PubMed ID: 20951351

DOI: 10.1016/j.devcel.2010.09.010

PubMed ID: 25902548

Title: Periodic retinoic acid-STRA8 signaling intersects with periodic germ-cell competencies to regulate spermatogenesis.

PubMed ID: 25902548

DOI: 10.1073/pnas.1505683112

PubMed ID: 32032549

Title: MEIOSIN Directs the Switch from Mitosis to Meiosis in Mammalian Germ Cells.

PubMed ID: 32032549

DOI: 10.1016/j.devcel.2020.01.010

PubMed ID: 32054698

Title: ZGLP1 is a determinant for the oogenic fate in mice.

PubMed ID: 32054698

DOI: 10.1126/science.aaw4115

Sequence Information:

  • Length: 393
  • Mass: 44555
  • Checksum: B81DBF3D28082E9F
  • Sequence:
    • MATPGEGNQP SDDGAPQPLA QLQKLEPRVV RRRLSQARHR ATLVGLFNNL RKAVYSQSDI 
TASKWQVLNR TKIHIQEQEE SLDKLLKLKA SFNLQDGNPN SLEEVKEEYA RMYSENDSVF 
LNSFLQDSPP EWFPSEAVGP DAEEEGEEEG EEEGEEGEEE EEGDEEGEEE EENGEEREVE 
EYQEEEEEEE EEEKKVDLSH SSSTLLPDLM EFERYLNFYK QTMDLLTMNS IISAHEVTLP 
IVSAAISHLW QTLSEEKKAR LLQVWEQQHS AFADLTEACL ELAGVEGSMK DSGVDSQGAS 
CSLESTPEEI LFEDAFDVAS FLDKSEAQHM SNISAMFATC NSENPEEKFQ LYIQIIEFFK 
SLGCVNTPLN QEPEPPDDDD AMLLKCLETF DDL

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.