Details for: Stx1a

Gene ID: 20907

Symbol: Stx1a

Ensembl ID: ENSMUSG00000007207

Description: syntaxin 1A (brain)

Associated with

Other Information

Genular Protein ID: 267594356

Symbol: STX1A_MOUSE

Name: Syntaxin-1A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 12101244

Title: Granuphilin modulates the exocytosis of secretory granules through interaction with syntaxin 1a.

PubMed ID: 12101244

DOI: 10.1128/mcb.22.15.5518-5526.2002

PubMed ID: 15774481

Title: Synaptotagmin VI and VIII and syntaxin 2 are essential for the mouse sperm acrosome reaction.

PubMed ID: 15774481

DOI: 10.1074/jbc.m412920200

PubMed ID: 17055430

Title: Otoferlin, defective in a human deafness form, is essential for exocytosis at the auditory ribbon synapse.

PubMed ID: 17055430

DOI: 10.1016/j.cell.2006.08.040

PubMed ID: 16452087

Title: Comprehensive identification of phosphorylation sites in postsynaptic density preparations.

PubMed ID: 16452087

DOI: 10.1074/mcp.t500041-mcp200

PubMed ID: 17502420

Title: Imaging analysis reveals mechanistic differences between first- and second-phase insulin exocytosis.

PubMed ID: 17502420

DOI: 10.1083/jcb.200608132

PubMed ID: 17296554

Title: Sept4, a component of presynaptic scaffold and Lewy bodies, is required for the suppression of alpha-synuclein neurotoxicity.

PubMed ID: 17296554

DOI: 10.1016/j.neuron.2007.01.019

PubMed ID: 18760330

Title: Leucine-rich glioma inactivated 3 associates with syntaxin 1.

PubMed ID: 18760330

DOI: 10.1016/j.neulet.2008.08.044

PubMed ID: 19196426

Title: Sept8 controls the binding of vesicle-associated membrane protein 2 to synaptophysin.

PubMed ID: 19196426

DOI: 10.1111/j.1471-4159.2008.05849.x

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 21998599

Title: Positional cloning of a type 2 diabetes quantitative trait locus; tomosyn-2, a negative regulator of insulin secretion.

PubMed ID: 21998599

DOI: 10.1371/journal.pgen.1002323

PubMed ID: 21445306

Title: Structure-function study of mammalian Munc18-1 and C. elegans UNC-18 implicates domain 3b in the regulation of exocytosis.

PubMed ID: 21445306

DOI: 10.1371/journal.pone.0017999

PubMed ID: 23341457

Title: PRIP (phospholipase C-related but catalytically inactive protein) inhibits exocytosis by direct interactions with syntaxin 1 and SNAP-25 through its C2 domain.

PubMed ID: 23341457

DOI: 10.1074/jbc.m112.419317

PubMed ID: 28596237

Title: The SNARE protein syntaxin-1a Plays an essential role in biphasic exocytosis of the incretin hormone glucagon-like peptide 1.

PubMed ID: 28596237

DOI: 10.2337/db16-1403

PubMed ID: 28031464

Title: New Roles of Syntaxin-1A in Insulin Granule Exocytosis and Replenishment.

PubMed ID: 28031464

DOI: 10.1074/jbc.m116.769885

PubMed ID: 28821673

Title: UNC-18 and Tomosyn Antagonistically Control Synaptic Vesicle Priming Downstream of UNC-13 in Caenorhabditis elegans.

PubMed ID: 28821673

DOI: 10.1523/jneurosci.0338-17.2017

PubMed ID: 29056747

Title: PRRT2 deficiency induces paroxysmal kinesigenic dyskinesia by regulating synaptic transmission in cerebellum.

PubMed ID: 29056747

DOI: 10.1038/cr.2017.128

Sequence Information:

  • Length: 288
  • Mass: 33054
  • Checksum: 8F8255F2EEF886CA
  • Sequence:
  • MKDRTQELRT AKDSDDDDDV TVTVDRDRFM DEFFEQVEEI RGFIDKIAEN VEEVKRKHSA 
    ILASPNPDEK TKEELEELMS DIKKTANKVR SKLKSIEQSI EQEEGLNRSS ADLRIRKTQH 
    STLSRKFVEV MSEYNATQSD YRERCKGRIQ RQLEITGRTT TSEELEDMLE SGNPAIFASG 
    IIMDSSISKQ ALSEIETRHS EIIKLETSIR ELHDMFMDMA MLVESQGEMI DRIEYNVEHA 
    VDYVERAVSD TKKAVKYQSK ARRKKIMIII CCVILGIIIA STIGGIFG

Genular Protein ID: 4244175686

Symbol: Q5D0A4_MOUSE

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

Sequence Information:

  • Length: 287
  • Mass: 32923
  • Checksum: 9B3D07F8B8CDDFD9
  • Sequence:
  • KDRTQELRTA KDSDDDDDVT VTVDRDRFMD EFFEQVEEIR GFIDKIAENV EEVKRKHSAI 
    LASPNPDEKT KEELEELMSD IKKTANKVRS KLKSIEQSIE QEEGLNRSSA DLRIRKTQHS 
    TLSRKFVEVM SEYNATQSDY RERCKGRIQR QLEITGRTTT SEELEDMLES GNPAIFASGI 
    IMDSSISKQA LSEIETRHSE IIKLETSIRE LHDMFMDMAM LVESQGEMID RIEYNVEHAV 
    DYVERAVSDT KKAVKYQSKA RRKKIMIIIC CVILGIIIAS TIGGIFG

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.