Genular: Defining Cellular Identity and Function

Details for: Supt5

Gene ID: 20924

Symbol: Supt5

Ensembl ID: ENSMUSG00000003435

Description: suppressor of Ty 5, DSIF elongation factor subunit

Associated with

Formation of rna pol ii elongation complex
(R-MMU-112382)
Formation of the early elongation complex
(R-MMU-113418)
Gene expression (transcription)
(R-MMU-74160)
Generic transcription pathway
(R-MMU-212436)
Metabolism of rna
(R-MMU-8953854)
Mrna capping
(R-MMU-72086)
Rna pol ii ctd phosphorylation and interaction with ce
(R-MMU-77075)
Rna polymerase ii pre-transcription events
(R-MMU-674695)
Rna polymerase ii transcribes snrna genes
(R-MMU-6807505)
Rna polymerase ii transcription
(R-MMU-73857)
Rna polymerase ii transcription elongation
(R-MMU-75955)
Tp53 regulates transcription of dna repair genes
(R-MMU-6796648)
Transcriptional regulation by tp53
(R-MMU-3700989)
Chromatin binding
(GO:0003682)
Dna-templated transcription elongation
(GO:0006354)
Dsif complex
(GO:0032044)
Enzyme binding
(GO:0019899)
Mrna binding
(GO:0003729)
Negative regulation of dna-templated transcription, elongation
(GO:0032785)
Negative regulation of transcription by rna polymerase ii
(GO:0000122)
Nucleoplasm
(GO:0005654)
Nucleus
(GO:0005634)
Positive regulation of dna-templated transcription, elongation
(GO:0032786)
Positive regulation of macroautophagy
(GO:0016239)
Positive regulation of transcription by rna polymerase ii
(GO:0045944)
Protein heterodimerization activity
(GO:0046982)
Regulation of dna-templated transcription elongation
(GO:0032784)
Regulation of transcription by rna polymerase ii
(GO:0006357)
Regulation of transcription elongation by rna polymerase ii
(GO:0034243)
Transcription elongation-coupled chromatin remodeling
(GO:0140673)
Transcription elongation by rna polymerase ii
(GO:0006368)

Other Information

Proteins

Transcription elongation factor SPT5

Genular Protein ID: 1660565413

Symbol: SPT5H_MOUSE

Name: Transcription elongation factor SPT5

UniProtKB Accession Codes:

O55201 Q3UJ77 Q3UJH1 Q3UKD7 Q3UM54 Q6PB73 Q6PDP0 Q6PFR4

Database IDs:

Citations:

PubMed ID: 9480761

Title: Isolation of murine SPT5 homologue: completion of the isolation and characterization of human and murine homologues of yeast chromatin structural protein complex SPT4, SPT5, and SPT6.

PubMed ID: 9480761

DOI: 10.1006/geno.1997.5137

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 17242355

Title: Large-scale phosphorylation analysis of mouse liver.

PubMed ID: 17242355

DOI: 10.1073/pnas.0609836104

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 23806337

Title: SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways.

PubMed ID: 23806337

DOI: 10.1016/j.molcel.2013.06.001

PubMed ID: 24129315

Title: Immunoaffinity enrichment and mass spectrometry analysis of protein methylation.

PubMed ID: 24129315

DOI: 10.1074/mcp.o113.027870

Sequence Information:

Length: 1082
Mass: 120664
Checksum: 109D0D8D2D71DDE7
Sequence:

MSDSEDSNFS EEEDSERSSE AEEAEVEEDQ RSAAGSEKEE EPEEEEEEEE EYDEEEEEED 
DDRPPKKPRH GGFILDEADV DDEYEDEDQW EDGAEDILEK EEIEASNIDN VVLDEDRSGA 
RRLQNLWRDQ REEELGEYYM KKYAKSSVGE TVYGGSDELS DDITQQQLLP GVKDPNLWTV 
KCKIGEERAT AISLMRKFIA YQFTDTPLQI KSVVAPEHVK GYIYVEAYKQ THVKQAIEGV 
GNLRLGYWNQ QMVPIKEMTD VLKVVKEVAN LKPKSWVRLK RGIYKDDIAQ VDYVEPSQNT 
ISLKMIPRID YDRIKARMSL KDWFAKRKKF KRPPQRLFDA EKIRSLGGDV ASDGDFLIFE 
GNRYSRKGFL FKSFAMSAVI TEGVKPTLSE LEKFEDQPEG IDLEVVTEST GKEREHNFQP 
GDNVEVCEGE LINLQGKVLS VDGNKITIMP KHEDLKDMLE FPAQELRKYF KMGDHVKVIA 
GRFEGDTGLI VRVEENFVIL FSDLTMHELK VLPRDLQLCS ETASGVDVGG QHEWGELVQL 
DPRTVGVIVR LERETFQVLN MHGKVVTVRH QAVTQKKDNR FAVALDSDQN NIHVKDIVKV 
IDGPHSGREG EIRHLYRSFA FLHCKKLVEN GGMFVCKARH LVLAGGSKPR DVTNLTVGGF 
TPMSPRISSP MHPSAEGQHG GFGSPGGMSR GRGRRDNELI GQTVRISQGP YKGYIGVVKD 
ATESTARVEL HSTCQTISVD RQRLTTVDSQ RPGGMTSTYG RTPMYGSQTP MYGSGSRTPM 
YGSQTPLQDG SRTPHYGSQT PLHDGSRTPA QSGAWDPNNP NTPSRAEEEY EYAFDDEPTP 
SPQAYGGTPN PQTPGYPDPS SPQVNPQYNP QTPGTPAMYN TDQFSPYAAP SPQGSYQPSP 
SPQSYHQVAP SPAGYQNTHS PASYHPTPSP MAYQASPSPS PVGYSPMTPG APSPGGYNPH 
TPGSGIEQNS SDWVTTDIQV KVRDTYLDTQ IVGQTGVIRS VTGGMCSVYL KDSEKVVSIS 
SEHLEPITPT KNNKVKVILG EDREATGVLL SIDGEDGIIR MDLEDQQIKI LNLRFLGKLL 
EA

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Supt5

Associated with

Other Information

Isolation of murine SPT5 homologue: completion of the isolation and characterization of human and murine homologues of yeast chromatin structural protein complex SPT4, SPT5, and SPT6. PubMed ID: 9480761

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Large-scale phosphorylation analysis of mouse liver. PubMed ID: 17242355

A tissue-specific atlas of mouse protein phosphorylation and expression. PubMed ID: 21183079

SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways. PubMed ID: 23806337

Immunoaffinity enrichment and mass spectrometry analysis of protein methylation. PubMed ID: 24129315