Details for: Suv39h1

Gene ID: 20937

Symbol: Suv39h1

Ensembl ID: ENSMUSG00000039231

Description: suppressor of variegation 3-9 1

Associated with

Other Information

Genular Protein ID: 1462922775

Symbol: SUV91_MOUSE

Name: Histone-lysine N-methyltransferase SUV39H1

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 10202156

Title: Functional mammalian homologues of the Drosophila PEV-modifier Su(var)3-9 encode centromere-associated proteins which complex with the heterochromatin component M31.

PubMed ID: 10202156

DOI: 10.1093/emboj/18.7.1923

PubMed ID: 10754099

Title: Molecular and genetic analysis of the mouse homolog of the Drosophila suppressor of position-effect variegation 3-9 gene.

PubMed ID: 10754099

DOI: 10.1007/s003350010049

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 19468303

Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.

PubMed ID: 19468303

DOI: 10.1371/journal.pbio.1000112

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 11094092

Title: Isolation and characterization of Suv39h2, a second histone H3 methyltransferase gene that displays testis-specific expression.

PubMed ID: 11094092

DOI: 10.1128/mcb.20.24.9423-9433.2000

PubMed ID: 10949293

Title: Regulation of chromatin structure by site-specific histone H3 methyltransferases.

PubMed ID: 10949293

DOI: 10.1038/35020506

PubMed ID: 11701123

Title: Loss of the Suv39h histone methyltransferases impairs mammalian heterochromatin and genome stability.

PubMed ID: 11701123

DOI: 10.1016/s0092-8674(01)00542-6

PubMed ID: 11788710

Title: Functional and physical interaction between the histone methyl transferase Suv39H1 and histone deacetylases.

PubMed ID: 11788710

DOI: 10.1093/nar/30.2.475

PubMed ID: 12867029

Title: Suv39h-mediated histone H3 lysine 9 methylation directs DNA methylation to major satellite repeats at pericentric heterochromatin.

PubMed ID: 12867029

DOI: 10.1016/s0960-9822(03)00432-9

PubMed ID: 14690609

Title: Partitioning and plasticity of repressive histone methylation states in mammalian chromatin.

PubMed ID: 14690609

DOI: 10.1016/s1097-2765(03)00477-5

PubMed ID: 14690610

Title: Histone methyltransferases direct different degrees of methylation to define distinct chromatin domains.

PubMed ID: 14690610

DOI: 10.1016/s1097-2765(03)00479-9

PubMed ID: 14702045

Title: Epigenetic regulation of telomere length in mammalian cells by the Suv39h1 and Suv39h2 histone methyltransferases.

PubMed ID: 14702045

DOI: 10.1038/ng1278

PubMed ID: 18004385

Title: SIRT1 regulates the histone methyl-transferase SUV39H1 during heterochromatin formation.

PubMed ID: 18004385

DOI: 10.1038/nature06268

PubMed ID: 17242355

Title: Large-scale phosphorylation analysis of mouse liver.

PubMed ID: 17242355

DOI: 10.1073/pnas.0609836104

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 23695662

Title: Depleting the methyltransferase Suv39h1 improves DNA repair and extends lifespan in a progeria mouse model.

PubMed ID: 23695662

DOI: 10.1038/ncomms2885

PubMed ID: 18619962

Title: A novel interaction between the proto-oncogene Evi1 and histone methyltransferases, SUV39H1 and G9a.

PubMed ID: 18619962

DOI: 10.1016/j.febslet.2008.06.056

PubMed ID: 24413057

Title: Temporal orchestration of repressive chromatin modifiers by circadian clock Period complexes.

PubMed ID: 24413057

DOI: 10.1038/nsmb.2746

PubMed ID: 30111536

Title: DCAF13 promotes pluripotency by negatively regulating SUV39H1 stability during early embryonic development.

PubMed ID: 30111536

DOI: 10.15252/embj.201898981

Sequence Information:

  • Length: 412
  • Mass: 47754
  • Checksum: 6B690F4FE7FD997C
  • Sequence:
  • MAENLKGCSV CCKSSWNQLQ DLCRLAKLSC PALGVSKKNL YDFEVEYLCD YKKIREQEYY 
    LVKWRGYPDS ENTWEPRQNL KCIRVLKQFH KDLERELVRR HRRSKPPRHL DPNLANYLVQ 
    KAKQRRALQR WEQELNAKRS HLGRITVENE VDLDGPPRSF VYINEYRVGE GITLNQVAVG 
    CECQDCLLAP TGGCCPGASL HKFAYNDQGQ VRLKAGQPIY ECNSRCCCGY DCPNRVVQKG 
    IRYDLCIFRT NDGRGWGVRT LEKIRKNSFV MEYVGEIITS EEAERRGQIY DRQGATYLFD 
    LDYVEDVYTV DAAYYGNISH FVNHSCDPNL QVYNVFIDNL DERLPRIAFF ATRTIWAGEE 
    LTFDYNMQVD PVDMESTRMD SNFGLAGLPG SPKKRVRIEC KCGTTACRKY LF

Genular Protein ID: 103718795

Symbol: A2AC19_MOUSE

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 17242355

Title: Large-scale phosphorylation analysis of mouse liver.

PubMed ID: 17242355

DOI: 10.1073/pnas.0609836104

PubMed ID: 19468303

Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.

PubMed ID: 19468303

DOI: 10.1371/journal.pbio.1000112

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

Sequence Information:

  • Length: 413
  • Mass: 47767
  • Checksum: 70C4F82BD7133F71
  • Sequence:
  • MGEPATLGCS VCCKSSWNQL QDLCRLAKLS CPALGVSKKN LYDFEVEYLC DYKKIREQEY 
    YLVKWRGYPD SENTWEPRQN LKCIRVLKQF HKDLERELVR RHRRSKPPRH LDPNLANYLV 
    QKAKQRRALQ RWEQELNAKR SHLGRITVEN EVDLDGPPRS FVYINEYRVG EGITLNQVAV 
    GCECQDCLLA PTGGCCPGAS LHKFAYNDQG QVRLKAGQPI YECNSRCCCG YDCPNRVVQK 
    GIRYDLCIFR TNDGRGWGVR TLEKIRKNSF VMEYVGEIIT SEEAERRGQI YDRQGATYLF 
    DLDYVEDVYT VDAAYYGNIS HFVNHSCDPN LQVYNVFIDN LDERLPRIAF FATRTIWAGE 
    ELTFDYNMQV DPVDMESTRM DSNFGLAGLP GSPKKRVRIE CKCGTTACRK YLF

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.