Genular: Defining Cellular Identity and Function

Details for: Sdc4

Gene ID: 20971

Symbol: Sdc4

Ensembl ID: ENSMUSG00000017009

Description: syndecan 4

Associated with

A tetrasaccharide linker sequence is required for gag synthesis
(R-MMU-1971475)
Cell surface interactions at the vascular wall
(R-MMU-202733)
Chondroitin sulfate/dermatan sulfate metabolism
(R-MMU-1793185)
Extracellular matrix organization
(R-MMU-1474244)
Glycosaminoglycan metabolism
(R-MMU-1630316)
Hemostasis
(R-MMU-109582)
Heparan sulfate/heparin (hs-gag) metabolism
(R-MMU-1638091)
Hs-gag biosynthesis
(R-MMU-2022928)
Hs-gag degradation
(R-MMU-2024096)
Metabolism
(R-MMU-1430728)
Metabolism of carbohydrates
(R-MMU-71387)
Metabolism of fat-soluble vitamins
(R-MMU-6806667)
Metabolism of vitamins and cofactors
(R-MMU-196854)
Non-integrin membrane-ecm interactions
(R-MMU-3000171)
Retinoid metabolism and transport
(R-MMU-975634)
Sensory perception
(R-MMU-9709957)
Syndecan interactions
(R-MMU-3000170)
Visual phototransduction
(R-MMU-2187338)
Cell migration
(GO:0016477)
Cell surface
(GO:0009986)
Costamere
(GO:0043034)
Extracellular region
(GO:0005576)
Fibronectin binding
(GO:0001968)
Focal adhesion
(GO:0005925)
Golgi lumen
(GO:0005796)
Identical protein binding
(GO:0042802)
Inner ear receptor cell stereocilium organization
(GO:0060122)
Membrane
(GO:0016020)
Negative regulation of t cell proliferation
(GO:0042130)
Neural tube closure
(GO:0001843)
Positive regulation of exosomal secretion
(GO:1903543)
Positive regulation of extracellular exosome assembly
(GO:1903553)
Positive regulation of focal adhesion assembly
(GO:0051894)
Positive regulation of stress fiber assembly
(GO:0051496)
Protein binding
(GO:0005515)
Protein kinase c binding
(GO:0005080)
Regulation of fibroblast migration
(GO:0010762)
Thrombospondin receptor activity
(GO:0070053)
Wound healing
(GO:0042060)

Other Information

Proteins

Ryudocan core protein

Genular Protein ID: 60356021

Symbol: SDC4_MOUSE

Name: Ryudocan core protein

UniProtKB Accession Codes:

O35988

Database IDs:

Citations:

PubMed ID: 9276666

Title: Molecular cloning, genomic organization, promoter activity, and tissue-specific expression of the mouse ryudocan gene.

PubMed ID: 9276666

DOI: 10.1093/oxfordjournals.jbchem.a021724

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 10684261

Title: Shedding of syndecan-1 and -4 ectodomains is regulated by multiple signaling pathways and mediated by a TIMP-3-sensitive metalloproteinase.

PubMed ID: 10684261

DOI: 10.1083/jcb.148.4.811

PubMed ID: 10911369

Title: Synectin, syndecan-4 cytoplasmic domain binding PDZ protein, inhibits cell migration.

PubMed ID: 10911369

DOI: 10.1002/1097-4652(200009)184:3<373::aid-jcp12>3.0.co;2-i

PubMed ID: 11805099

Title: Syndesmos, a syndecan-4 cytoplasmic domain interactor, binds to the focal adhesion adaptor proteins paxillin and Hic-5.

PubMed ID: 11805099

DOI: 10.1074/jbc.m110291200

PubMed ID: 15694365

Title: Dynamin II interacts with syndecan-4, a regulator of focal adhesion and stress-fiber formation.

PubMed ID: 15694365

DOI: 10.1016/j.bbrc.2004.12.179

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

Sequence Information:

Length: 198
Mass: 21482
Checksum: 4246963EC6A25915
Sequence:

MAPACLLAPL LLLLLGGFPL VPGESIRETE VIDPQDLLEG RYFSGALPDD EDAGGSDDFE 
LSGSGDLDDT EEPRPFPEVI EPLVPLDNHI PENAQPGIRV PSEPKELEEN EVIPKRAPSD 
VGDDMSNKVS MSSTAQGSNI FERTEVLAAL IVGGVVGILF AVFLILLLVY RMKKKDEGSY 
DLGKKPIYKK APTNEFYA

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Sdc4

Associated with

Other Information

Molecular cloning, genomic organization, promoter activity, and tissue-specific expression of the mouse ryudocan gene. PubMed ID: 9276666

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Shedding of syndecan-1 and -4 ectodomains is regulated by multiple signaling pathways and mediated by a TIMP-3-sensitive metalloproteinase. PubMed ID: 10684261

Synectin, syndecan-4 cytoplasmic domain binding PDZ protein, inhibits cell migration. PubMed ID: 10911369

Syndesmos, a syndecan-4 cytoplasmic domain interactor, binds to the focal adhesion adaptor proteins paxillin and Hic-5. PubMed ID: 11805099

Dynamin II interacts with syndecan-4, a regulator of focal adhesion and stress-fiber formation. PubMed ID: 15694365

A tissue-specific atlas of mouse protein phosphorylation and expression. PubMed ID: 21183079