Genular: Defining Cellular Identity and Function

Details for: Syt4

Gene ID: 20983

Symbol: Syt4

Ensembl ID: ENSMUSG00000024261

Description: synaptotagmin IV

Associated with

Astrocyte projection
(GO:0097449)
Axon
(GO:0030424)
Calcium-dependent phospholipid binding
(GO:0005544)
Calcium ion-regulated exocytosis of neurotransmitter
(GO:0048791)
Calcium ion binding
(GO:0005509)
Cell differentiation
(GO:0030154)
Cellular response to calcium ion
(GO:0071277)
Clathrin binding
(GO:0030276)
Cytoplasmic vesicle
(GO:0031410)
Dendrite
(GO:0030425)
Dense core granule
(GO:0031045)
Dense core granule cytoskeletal transport
(GO:0099519)
Exocytic vesicle
(GO:0070382)
Glutamatergic synapse
(GO:0098978)
Golgi apparatus
(GO:0005794)
Membrane
(GO:0016020)
Memory
(GO:0007613)
Metal ion binding
(GO:0046872)
Microvesicle
(GO:1990742)
Negative regulation of calcium ion-dependent exocytosis
(GO:0045955)
Negative regulation of catecholamine secretion
(GO:0033604)
Negative regulation of dense core granule exocytosis
(GO:1905414)
Negative regulation of neurotransmitter secretion
(GO:0046929)
Negative regulation of protein secretion
(GO:0050709)
Negative regulation of retrograde trans-synaptic signaling by neuropeptide
(GO:1905433)
Negative regulation of short-term neuronal synaptic plasticity
(GO:0048174)
Negative regulation of synaptic vesicle exocytosis
(GO:2000301)
Negative regulation of vesicle fusion
(GO:0031339)
Neuronal cell body
(GO:0043025)
Neuronal dense core vesicle
(GO:0098992)
Neuronal dense core vesicle membrane
(GO:0099012)
Neuron projection
(GO:0043005)
Neuron projection terminus
(GO:0044306)
Neurotransmitter secretion
(GO:0007269)
Perinuclear region of cytoplasm
(GO:0048471)
Phosphatidylserine binding
(GO:0001786)
Plasma membrane
(GO:0005886)
Positive regulation of dendrite extension
(GO:1903861)
Positive regulation of dense core granule exocytosis
(GO:1905415)
Positive regulation of glutamate secretion
(GO:0014049)
Postsynapse
(GO:0098794)
Presynapse
(GO:0098793)
Protein heterodimerization activity
(GO:0046982)
Protein homodimerization activity
(GO:0042803)
Regulation of calcium ion-dependent exocytosis
(GO:0017158)
Regulation of dopamine secretion
(GO:0014059)
Regulation of endocytosis
(GO:0030100)
Regulation of postsynaptic dense core vesicle exocytosis
(GO:0150044)
Regulation of trans-synaptic signaling by bdnf, modulating synaptic transmission
(GO:0150035)
Regulation of vesicle fusion
(GO:0031338)
Secretory granule maturation
(GO:0061792)
Secretory granule membrane
(GO:0030667)
Snare binding
(GO:0000149)
Somatodendritic compartment
(GO:0036477)
Synapse
(GO:0045202)
Synaptic vesicle
(GO:0008021)
Synaptic vesicle transport
(GO:0048489)
Syntaxin-1 binding
(GO:0017075)
Syntaxin-3 binding
(GO:0030348)
Syntaxin binding
(GO:0019905)
Vesicle
(GO:0031982)
Vesicle fusion
(GO:0006906)
Vesicle fusion with vesicle
(GO:0061782)

Other Information

Proteins

Synaptotagmin-4

Genular Protein ID: 4258827487

Symbol: SYT4_MOUSE

Name: Synaptotagmin-4

UniProtKB Accession Codes:

P40749 Q3UFC1 Q8BGH3 Q8BRL6

Database IDs:

Citations:

PubMed ID: 8058779

Title: A third synaptotagmin gene, Syt3, in the mouse.

PubMed ID: 8058779

DOI: 10.1073/pnas.91.17.8195

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 29166604

Title: Capture of Dense Core Vesicles at Synapses by JNK-Dependent Phosphorylation of Synaptotagmin-4.

PubMed ID: 29166604

DOI: 10.1016/j.celrep.2017.10.084

Sequence Information:

Length: 425
Mass: 47659
Checksum: 9A01144898CDFCEB
Sequence:

MAPITTSRVE FDEIPTVVGI FSAFGLVFTV SLFAWICCQR RSAKSNKTPP YKFVHVLKGV 
DIYPENLSSK KKFGGDDKSE VKGKAALPNL SLHLDLEKRD LNGNFPKANP KAGSSSDLEN 
VTPKLFTETE KEANSPESLK SSTSLTSEEK QEKLGTLFLS LEYNFEKKAF VVNIKEAQGL 
PAMDEQSMTS DPYIKMTILP EKKHRVKTRV LRKTLDPVFD ETFTFYGIPY PHIQELSLHF 
TVLSFDRFSR DDVIGEVLIP LSGIELSDGK MLMTREIIKR NAKKSSGRGE LLVSLCYQST 
TNTLTVVVLK ARHLPKSDVS GLSDPYVKVN LYHAKKRISK KKTHVKKCTP NAVFNELFVF 
DIPCESLEEI SVEFLVLDSE RGSRNEVIGR LVLGATAEGS GGGHWKEICD FPRRQIAKWH 
MLCDG

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Syt4

Associated with

Other Information

A third synaptotagmin gene, Syt3, in the mouse. PubMed ID: 8058779

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334