Genular: Defining Cellular Identity and Function

Details for: T

Gene ID: 20997

Symbol: T

Ensembl ID: ENSMUSG00000062327

Description: brachyury, T-box transcription factor T

Associated with

Anatomical structure morphogenesis
(GO:0009653)
Anterior/posterior pattern specification
(GO:0009952)
Bone morphogenesis
(GO:0060349)
Cardiac muscle cell differentiation
(GO:0055007)
Cardiac muscle cell myoblast differentiation
(GO:0060379)
Cell fate specification
(GO:0001708)
Cell population proliferation
(GO:0008283)
Chromatin
(GO:0000785)
Cytoplasm
(GO:0005737)
Determination of heart left/right asymmetry
(GO:0061371)
Dna-binding transcription factor activity
(GO:0003700)
Dna-binding transcription factor activity, rna polymerase ii-specific
(GO:0000981)
Dna binding
(GO:0003677)
Embryonic skeletal system development
(GO:0048706)
Heart morphogenesis
(GO:0003007)
Mesoderm development
(GO:0007498)
Mesoderm formation
(GO:0001707)
Mesoderm migration involved in gastrulation
(GO:0007509)
Multicellular organism development
(GO:0007275)
Negative regulation of dna-binding transcription factor activity
(GO:0043433)
Negative regulation of transcription by rna polymerase ii
(GO:0000122)
Neural plate morphogenesis
(GO:0001839)
Neural tube closure
(GO:0001843)
Notochord development
(GO:0030903)
Notochord formation
(GO:0014028)
Nucleoplasm
(GO:0005654)
Nucleus
(GO:0005634)
Penetration of zona pellucida
(GO:0007341)
Positive regulation of cell population proliferation
(GO:0008284)
Positive regulation of dna-templated transcription
(GO:0045893)
Positive regulation of transcription by rna polymerase ii
(GO:0045944)
Post-anal tail morphogenesis
(GO:0036342)
Protein binding
(GO:0005515)
Regulation of dna-templated transcription
(GO:0006355)
Regulation of transcription by rna polymerase ii
(GO:0006357)
Reproductive process
(GO:0022414)
Rna polymerase ii-specific dna-binding transcription factor binding
(GO:0061629)
Rna polymerase ii cis-regulatory region sequence-specific dna binding
(GO:0000978)
Sequence-specific dna binding
(GO:0043565)
Sequence-specific double-stranded dna binding
(GO:1990837)
Signal transduction involved in regulation of gene expression
(GO:0023019)
Somitogenesis
(GO:0001756)
Transcription by rna polymerase ii
(GO:0006366)
Vasculogenesis
(GO:0001570)

Other Information

Proteins

Protein T

Genular Protein ID: 321751035

Symbol: TBXT_MOUSE

Name: Protein T

UniProtKB Accession Codes:

P20293

Database IDs:

Citations:

PubMed ID: 2154694

Title: Cloning of the T gene required in mesoderm formation in the mouse.

PubMed ID: 2154694

DOI: 10.1038/343617a0

PubMed ID: 8344258

Title: The Brachyury gene encodes a novel DNA binding protein.

PubMed ID: 8344258

DOI: 10.1002/j.1460-2075.1993.tb05990.x

PubMed ID: 7588606

Title: The T protein encoded by Brachyury is a tissue-specific transcription factor.

PubMed ID: 7588606

DOI: 10.1002/j.1460-2075.1995.tb00158.x

Sequence Information:

Length: 436
Mass: 47440
Checksum: 1A0BDF9BA7FC2484
Sequence:

MSSPGTESAG KSLQYRVDHL LSAVESELQA GSEKGDPTER ELRVGLEESE LWLRFKELTN 
EMIVTKNGRR MFPVLKVNVS GLDPNAMYSF LLDFVTADNH RWKYVNGEWV PGGKPEPQAP 
SCVYIHPDSP NFGAHWMKAP VSFSKVKLTN KLNGGGQIML NSLHKYEPRI HIVRVGGPQR 
MITSHCFPET QFIAVTAYQN EEITALKIKY NPFAKAFLDA KERNDHKDVM EEPGDCQQPG 
YSQWGWLVPG AGTLCPPASS HPQFGGSLSL PSTHGCERYP ALRNHRSSPY PSPYAHRNSS 
PTYADNSSAC LSMLQSHDNW SSLGVPGHTS MLPVSHNASP PTGSSQYPSL WSVSNGTITP 
GSQTAGVSNG LGAQFFRGSP AHYTPLTHTV SAATSSSSGS PMYEGAATVT DISDSQYDTA 
QSLLIASWTP VSPPSM

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.