Details for: ABCA3
Associated with
Other Information
Genular Protein ID: 4186138437
Symbol: ABCA3_HUMAN
Name: ABC-C transporter
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 8706931
Title: Primary structure of a novel ABC transporter with a chromosomal localization on the band encoding the multidrug resistance-associated protein.
PubMed ID: 8706931
PubMed ID: 9027511
Title: The cloning of a human ABC gene (ABC3) mapping to chromosome 16p13.3.
PubMed ID: 9027511
PubMed ID: 11718719
Title: ABCA3 is a lamellar body membrane protein in human lung alveolar type II cells.
PubMed ID: 11718719
PubMed ID: 15616553
Title: The sequence and analysis of duplication-rich human chromosome 16.
PubMed ID: 15616553
DOI: 10.1038/nature03187
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 22673903
Title: Quantitative maps of protein phosphorylation sites across 14 different rat organs and tissues.
PubMed ID: 22673903
DOI: 10.1038/ncomms1871
PubMed ID: 16959783
Title: Characterization and classification of ATP-binding cassette transporter ABCA3 mutants in fatal surfactant deficiency.
PubMed ID: 16959783
PubMed ID: 17574245
Title: ABCA3-mediated choline-phospholipids uptake into intracellular vesicles in A549 cells.
PubMed ID: 17574245
PubMed ID: 20863830
Title: The surfactant lipid transporter ABCA3 is N-terminally cleaved inside LAMP3-positive vesicles.
PubMed ID: 20863830
PubMed ID: 24142515
Title: Disruption of N-linked glycosylation promotes proteasomal degradation of the human ATP-binding cassette transporter ABCA3.
PubMed ID: 24142515
PubMed ID: 25817392
Title: ABCA3 protects alveolar epithelial cells against free cholesterol induced cell death.
PubMed ID: 25817392
PubMed ID: 27352740
Title: Homooligomerization of ABCA3 and its functional significance.
PubMed ID: 27352740
PubMed ID: 26903515
Title: Functional Validation of ABCA3 as a Miltefosine Transporter in Human Macrophages: IMPACT ON INTRACELLULAR SURVIVAL OF LEISHMANIA (VIANNIA) PANAMENSIS.
PubMed ID: 26903515
PubMed ID: 27031696
Title: Analysis of the Proteolytic Processing of ABCA3: Identification of Cleavage Site and Involved Proteases.
PubMed ID: 27031696
PubMed ID: 28887056
Title: Quantification of volume and lipid filling of intracellular vesicles carrying the ABCA3 transporter.
PubMed ID: 28887056
PubMed ID: 31473345
Title: Metabolic labelling of choline phospholipids probes ABCA3 transport in lamellar bodies.
PubMed ID: 31473345
PubMed ID: 15044640
Title: ABCA3 gene mutations in newborns with fatal surfactant deficiency.
PubMed ID: 15044640
DOI: 10.1056/nejmoa032178
PubMed ID: 15976379
Title: ABCA3 mutations associated with pediatric interstitial lung disease.
PubMed ID: 15976379
PubMed ID: 16728712
Title: Alteration of the pulmonary surfactant system in full-term infants with hereditary ABCA3 deficiency.
PubMed ID: 16728712
PubMed ID: 16959974
Title: The consensus coding sequences of human breast and colorectal cancers.
PubMed ID: 16959974
PubMed ID: 25712598
Title: Respiratory failure in a term infant with cis and trans mutations in ABCA3.
PubMed ID: 25712598
DOI: 10.1038/jp.2014.236
PubMed ID: 27177387
Title: Tools to explore ABCA3 mutations causing interstitial lung disease.
PubMed ID: 27177387
DOI: 10.1002/ppul.23471
Sequence Information:
- Length: 1704
- Mass: 191362
- Checksum: 606735C504839D0D
- Sequence:
MAVLRQLALL LWKNYTLQKR KVLVTVLELF LPLLFSGILI WLRLKIQSEN VPNATIYPGQ SIQELPLFFT FPPPGDTWEL AYIPSHSDAA KTVTETVRRA LVINMRVRGF PSEKDFEDYI RYDNCSSSVL AAVVFEHPFN HSKEPLPLAV KYHLRFSYTR RNYMWTQTGS FFLKETEGWH TTSLFPLFPN PGPREPTSPD GGEPGYIREG FLAVQHAVDR AIMEYHADAA TRQLFQRLTV TIKRFPYPPF IADPFLVAIQ YQLPLLLLLS FTYTALTIAR AVVQEKERRL KEYMRMMGLS SWLHWSAWFL LFFLFLLIAA SFMTLLFCVK VKPNVAVLSR SDPSLVLAFL LCFAISTISF SFMVSTFFSK ANMAAAFGGF LYFFTYIPYF FVAPRYNWMT LSQKLCSCLL SNVAMAMGAQ LIGKFEAKGM GIQWRDLLSP VNVDDDFCFG QVLGMLLLDS VLYGLVTWYM EAVFPGQFGV PQPWYFFIMP SYWCGKPRAV AGKEEEDSDP EKALRNEYFE AEPEDLVAGI KIKHLSKVFR VGNKDRAAVR DLNLNLYEGQ ITVLLGHNGA GKTTTLSMLT GLFPPTSGRA YISGYEISQD MVQIRKSLGL CPQHDILFDN LTVAEHLYFY AQLKGLSRQK CPEEVKQMLH IIGLEDKWNS RSRFLSGGMR RKLSIGIALI AGSKVLILDE PTSGMDAISR RAIWDLLQRQ KSDRTIVLTT HFMDEADLLG DRIAIMAKGE LQCCGSSLFL KQKYGAGYHM TLVKEPHCNP EDISQLVHHH VPNATLESSA GAELSFILPR ESTHRFEGLF AKLEKKQKEL GIASFGASIT TMEEVFLRVG KLVDSSMDIQ AIQLPALQYQ HERRASDWAV DSNLCGAMDP SDGIGALIEE ERTAVKLNTG LALHCQQFWA MFLKKAAYSW REWKMVAAQV LVPLTCVTLA LLAINYSSEL FDDPMLRLTL GEYGRTVVPF SVPGTSQLGQ QLSEHLKDAL QAEGQEPREV LGDLEEFLIF RASVEGGGFN ERCLVAASFR DVGERTVVNA LFNNQAYHSP ATALAVVDNL LFKLLCGPHA SIVVSNFPQP RSALQAAKDQ FNEGRKGFDI ALNLLFAMAF LASTFSILAV SERAVQAKHV QFVSGVHVAS FWLSALLWDL ISFLIPSLLL LVVFKAFDVR AFTRDGHMAD TLLLLLLYGW AIIPLMYLMN FFFLGAATAY TRLTIFNILS GIATFLMVTI MRIPAVKLEE LSKTLDHVFL VLPNHCLGMA VSSFYENYET RRYCTSSEVA AHYCKKYNIQ YQENFYAWSA PGVGRFVASM AASGCAYLIL LFLIETNLLQ RLRGILCALR RRRTLTELYT RMPVLPEDQD VADERTRILA PSPDSLLHTP LIIKELSKVY EQRVPLLAVD RLSLAVQKGE CFGLLGFNGA GKTTTFKMLT GEESLTSGDA FVGGHRISSD VGKVRQRIGY CPQFDALLDH MTGREMLVMY ARLRGIPERH IGACVENTLR GLLLEPHANK LVRTYSGGNK RKLSTGIALI GEPAVIFLDE PSTGMDPVAR RLLWDTVARA RESGKAIIIT SHSMEECEAL CTRLAIMVQG QFKCLGSPQH LKSKFGSGYS LRAKVQSEGQ QEALEEFKAF VDLTFPGSVL EDEHQGMVHY HLPGRDLSWA KVFGILEKAK EKYGVDDYSV SQISLEQVFL SFAHLQPPTA EEGR
Genular Protein ID: 3319153392
Symbol: Q4LE27_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Sequence Information:
- Length: 1708
- Mass: 191318
- Checksum: E64C1D2ACEDA199B
- Sequence:
TAPPPSPSLP LQDRAATSAH LALFTLSFQS TFLLFPAGCS AYLNLLRPPT SLAALGVPFS KTMAVLRQLA LLLWKNYTLQ KRKVLVTVLE LFLPLLFSGI LIWLRLKIQS ENVPNATIYP GQSIQELPLF FTFPPPGDTW ELAYIPSHSD AAKTVTETVR RALVINMRVR GFPSEKDFED YIRYDNCSSS VLAAVVFEHP FNHSKEPLPL AVKYHLRFSY TRRNYMWTQT GSFFLKETEG WHTTSLFPLF PNPGPREPTS PDGGEPGYIR EGFLAVQHAV DRAIMEYHAD AATRQLFQRL TVTIKRFPYP PFIADPFLVA IQYQLPLLLL LSFTYTALTI ARAVVQEKER RLKEYMRMMG LSSWLHWSAW FLLFFLFLLI AASFMTLLFC VKVKPNVAVL SRSDPSLVLA FLLCFAISTI SFSFMVSTFF SKGMGIQWRD LLSPVNVDDD FCFGQVLGML LLDSVLYGLV TWYMEAVFPG QFGVPQPWYF FIMPSYWCGK PRAVAGKEEE DSDPEKALRN EYFEAEPEDL VAGIKIKHLS KVFRVGNKDR AAVRDLNLNL YEGQITVLLG HNGAGKTTTL SMLTGLFPPT SGRAYISGYE ISQDMVQIRK SLGLCPQHDI LFDNLTVAEH LYFYAQLKGL SRQKCPEEVK QMLHIIGLED KWNSRSRFLS GGMRRKLSIG IALIAGSKVL ILDEPTSGMD AISRRAIWDL LQRQKSDRTI VLTTHFMDEA DLLGDRIAIM AKGELQCCGS SLFLKQKYGA GYHMTLVKEP HCNPEDISQL VHHHVPNATL ESSAGAELSF ILPRESTHRF EGLFAKLEKK QKELGIASFG ASITTMEEVF LRVGKLVDSS MDIQAIQLPA LQYQHERRAS DWAVDSNLCG AMDPSDGIGA LIEEERTAVK LNTGLALHCQ QFWAMFLKKA AYSWREWKMV AAQVLVPLTC VTLALLAINY SSELFDDPML RLTLGEYGRT VVPFSVPGTS QLGQQLSEHL KDALQAEGQE PREVLGDLEE FLIFRASVEG GGFNERCLVA ASFRDVGERT VVNALFNNQA YHSPATALAV VDNLLFKLLC GPHASIVVSN FPQPRSALQA AKDQFNEGRK GFDIALNLLF AMAFLASTFS ILAVSERAVQ AKHVQFVSGV HVASFWLSAL LWDLISFLIP SLLLLVVFKA FDVRAFTRDG HMADTLLLLL LYGWAIIPLM YLMNFFFLGA ATAYTRLTIF NILSGIATFL MVTIMRIPAV KLEELSKTLD HVFLVLPNHC LGMAVSSFYE NYETRRYCTS SEVAAHYCKK YNIQYQENFY AWSAPGVGRF VASMAASGCA YLILLFLIET NLLQRLRGIL CALRRRRTLT ELYTRMPVLP EDQDVADERT RILAPSPDSL LHTPLIIKEL SKVYEQRVPL LAVDRLSLAV QKGECFGLLG FNGAGKTTTF KMLTGEESLT SGDAFVGGHR ISSDVGKVRQ RIGYCPQFDA LLDHMTGREM LVMYARLRGI PERHIGACVE NTLRGLLLEP HANKLVRTYS GGNKRKLSTG IALIGEPAVI FLDEPSTGMD PVARRLLWDT VARARESGKA IIITSHSMEE CEALCTRLAI MVQGQFKCLG SPQHLKSKFG SGYSLRAKVQ SEGQQEALEE FKAFVDLTFP GSVLEDEHQG MVHYHLPGRD LSWAKVFGIL EKAKEKYGVD DYSVSQISLE QVFLSFAHLQ PPTAEEGR
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.