Details for: ALAD

Gene ID: 210

Symbol: ALAD

Ensembl ID: ENSG00000148218

Description: aminolevulinate dehydratase

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 78.1215
    Cell Significance Index: -19.8200
  • Cell Name: embryonic stem cell (CL0002322)
    Fold Change: 55.6867
    Cell Significance Index: -22.9400
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 43.9131
    Cell Significance Index: -17.8400
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 18.6961
    Cell Significance Index: -17.8500
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 13.6298
    Cell Significance Index: -16.8100
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 7.2046
    Cell Significance Index: -19.3000
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 5.6639
    Cell Significance Index: -22.3500
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 2.8557
    Cell Significance Index: -6.2500
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 1.9594
    Cell Significance Index: 135.5100
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 1.6898
    Cell Significance Index: 23.0600
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: 1.5344
    Cell Significance Index: 178.8200
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: 1.1911
    Cell Significance Index: 31.9200
  • Cell Name: paneth cell of colon (CL0009009)
    Fold Change: 0.6040
    Cell Significance Index: 9.0500
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.5508
    Cell Significance Index: 109.3000
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.5433
    Cell Significance Index: 24.6300
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.4880
    Cell Significance Index: 14.0600
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.4650
    Cell Significance Index: 93.2800
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 0.4480
    Cell Significance Index: 20.8900
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.3280
    Cell Significance Index: 59.1300
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 0.2948
    Cell Significance Index: 22.6200
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 0.2916
    Cell Significance Index: 15.1500
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 0.2791
    Cell Significance Index: 35.7900
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.2663
    Cell Significance Index: 50.6700
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: 0.2449
    Cell Significance Index: 6.4400
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: 0.2402
    Cell Significance Index: 15.1400
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.2243
    Cell Significance Index: 80.4600
  • Cell Name: proerythroblast (CL0000547)
    Fold Change: 0.2034
    Cell Significance Index: 2.9200
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 0.1961
    Cell Significance Index: 5.4800
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.1861
    Cell Significance Index: 286.4500
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.1705
    Cell Significance Index: 314.3600
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.1449
    Cell Significance Index: 130.8700
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.1406
    Cell Significance Index: 19.3100
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.1395
    Cell Significance Index: 76.1900
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.1311
    Cell Significance Index: 57.9500
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.1295
    Cell Significance Index: 15.9200
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: 0.1196
    Cell Significance Index: 2.9900
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.1004
    Cell Significance Index: 69.4600
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: 0.0832
    Cell Significance Index: 6.2000
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.0690
    Cell Significance Index: 6.8300
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: 0.0536
    Cell Significance Index: 2.8200
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: 0.0487
    Cell Significance Index: 1.5600
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: 0.0451
    Cell Significance Index: 2.7700
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: 0.0373
    Cell Significance Index: 0.6400
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: 0.0277
    Cell Significance Index: 4.7300
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: 0.0267
    Cell Significance Index: 1.8900
  • Cell Name: lactocyte (CL0002325)
    Fold Change: 0.0148
    Cell Significance Index: 1.9200
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.0011
    Cell Significance Index: 2.0800
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0003
    Cell Significance Index: -0.4500
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.0068
    Cell Significance Index: -0.3000
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0103
    Cell Significance Index: -7.5400
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: -0.0143
    Cell Significance Index: -0.9200
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0144
    Cell Significance Index: -9.1300
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0204
    Cell Significance Index: -15.4700
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0274
    Cell Significance Index: -20.2900
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: -0.0336
    Cell Significance Index: -1.1800
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: -0.0359
    Cell Significance Index: -4.2300
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: -0.0359
    Cell Significance Index: -0.7700
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0377
    Cell Significance Index: -17.1200
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0383
    Cell Significance Index: -21.5800
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0400
    Cell Significance Index: -24.9700
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0414
    Cell Significance Index: -4.2300
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: -0.0442
    Cell Significance Index: -1.1800
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0556
    Cell Significance Index: -16.0100
  • Cell Name: retinal rod cell (CL0000604)
    Fold Change: -0.0608
    Cell Significance Index: -0.7200
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -0.0632
    Cell Significance Index: -2.4000
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.0645
    Cell Significance Index: -4.3400
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0819
    Cell Significance Index: -11.9100
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: -0.0871
    Cell Significance Index: -2.3700
  • Cell Name: pro-T cell (CL0000827)
    Fold Change: -0.0922
    Cell Significance Index: -2.3600
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.1081
    Cell Significance Index: -12.3800
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.1158
    Cell Significance Index: -24.4000
  • Cell Name: foveolar cell of stomach (CL0002179)
    Fold Change: -0.1396
    Cell Significance Index: -0.9100
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.1411
    Cell Significance Index: -6.6300
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.1511
    Cell Significance Index: -8.4800
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.1947
    Cell Significance Index: -15.4200
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.2065
    Cell Significance Index: -21.5000
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: -0.2343
    Cell Significance Index: -4.9100
  • Cell Name: umbrella cell of urothelium (CL4030056)
    Fold Change: -0.2432
    Cell Significance Index: -2.2400
  • Cell Name: intestinal epithelial cell (CL0002563)
    Fold Change: -0.2478
    Cell Significance Index: -2.5700
  • Cell Name: centrilobular region hepatocyte (CL0019029)
    Fold Change: -0.2490
    Cell Significance Index: -4.2000
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: -0.2516
    Cell Significance Index: -4.2100
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: -0.2647
    Cell Significance Index: -13.7900
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: -0.2876
    Cell Significance Index: -6.2300
  • Cell Name: regular ventricular cardiac myocyte (CL0002131)
    Fold Change: -0.3213
    Cell Significance Index: -4.1200
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: -0.3442
    Cell Significance Index: -11.9600
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: -0.3556
    Cell Significance Index: -10.4500
  • Cell Name: helper T cell (CL0000912)
    Fold Change: -0.3561
    Cell Significance Index: -5.0600
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.3582
    Cell Significance Index: -21.9600
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: -0.3680
    Cell Significance Index: -9.4600
  • Cell Name: cortical interneuron (CL0008031)
    Fold Change: -0.3832
    Cell Significance Index: -9.1900
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: -0.4251
    Cell Significance Index: -11.3700
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: -0.4298
    Cell Significance Index: -12.6600
  • Cell Name: cardiac muscle cell (CL0000746)
    Fold Change: -0.4399
    Cell Significance Index: -6.5000
  • Cell Name: hepatoblast (CL0005026)
    Fold Change: -0.4548
    Cell Significance Index: -7.6500
  • Cell Name: primitive red blood cell (CL0002355)
    Fold Change: -0.4629
    Cell Significance Index: -5.2400
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.4678
    Cell Significance Index: -14.9000
  • Cell Name: stratified epithelial cell (CL0000079)
    Fold Change: -0.4694
    Cell Significance Index: -17.2300
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.4746
    Cell Significance Index: -15.5400
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -0.4813
    Cell Significance Index: -16.8600
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: -0.5010
    Cell Significance Index: -10.9700

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** 1. **Catalytic Activity:** ALAD is a metalloenzyme that utilizes iron as a cofactor to catalyze the dehydration of ALA to PBG. 2. **Subcellular Localization:** ALAD is primarily found in the cytosol, although it can also be detected in the nucleus and extracellular spaces. 3. **Cellular Expression:** ALAD is widely expressed in various cell types, including erythroid progenitor cells, lens epithelial cells, and pulmonary interstitial fibroblasts. 4. **Regulation:** ALAD activity is tightly regulated by feedback inhibition, which prevents excessive heme synthesis and maintains cellular homeostasis. **Pathways and Functions:** 1. **Heme Biosynthesis:** ALAD is a critical enzyme in the heme biosynthetic pathway, which involves the conversion of ALA to PBG, followed by the formation of protoporphyrin IX, and finally, the assembly of heme. 2. **Immune System:** ALAD plays a role in regulating immune responses by modulating the production of cytokines and chemokines, which are essential for immune cell activation and function. 3. **Antioxidant Defense:** ALAD has been implicated in the regulation of oxidative stress by modulating the production of reactive oxygen species (ROS). 4. **Neuroprotection:** ALAD has been shown to have neuroprotective effects by regulating the expression of genes involved in neuronal survival and function. **Clinical Significance:** 1. **Heme Disorders:** Mutations in the ALAD gene can lead to heme disorders, such as porphyria cutanea tarda (PCT), a condition characterized by skin blistering and scarring. 2. **Cancer:** ALAD has been implicated in the regulation of cancer cell growth and survival, and its dysregulation has been associated with various types of cancer. 3. **Neurological Disorders:** ALAD has been linked to neurological disorders, such as Alzheimer's disease and Parkinson's disease, where heme biosynthesis is disrupted. 4. **Toxicity:** Exposure to heavy metals, such as lead and mercury, can disrupt ALAD activity, leading to oxidative stress and cellular damage. In conclusion, ALAD is a vital enzyme that plays a critical role in heme biosynthesis, immune function, and antioxidant defense. Its dysregulation has been implicated in various diseases, highlighting the importance of understanding the molecular mechanisms underlying its function. Further research is needed to elucidate the complex relationships between ALAD, heme biosynthesis, and disease.

Genular Protein ID: 2248547344

Symbol: HEM2_HUMAN

Name: Delta-aminolevulinic acid dehydratase

UniProtKB Accession Codes:

P13716 A8K375 B2R6F2 Q16870 Q16871 Q9BVQ9

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 BRENDA 1 Bgee 1 BindingDB 1 BioCyc 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CDD 1 CTD 1 ChEBI 14 ChEMBL 1 ChiTaRS 1 DMDM 1 DNASU 1 DisGeNET 1 DrugBank 8 EC 2 EMBL 9 Ensembl 1 EvolutionaryTrace 1 ExpressionAtlas 1 GO 43 Gene3D 1 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 3 KEGG 1 MANE-Select 1 MIM 3 MalaCards 1 MassIVE 1 MetOSite 1 MoonDB 1 MoonProt 1 NCBI Taxonomy 1 OGP 1 OMA 1 OpenTargets 1 Orphanet 1 OrthoDB 1 PANTHER 2 PDB 4 PDBsum 4 PIR 1 PIRSF 1 PRINTS 1 PRO 1 PROSITE 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 2 Pumba 1 REPRODUCTION-2DPAGE 1 RNAct 1 Reactome 2 RefSeq 3 Rhea 1 SMART 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 SwissPalm 1 TreeFam 1 UCSC 1 UniPathway 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 3463993

Title: Human delta-aminolevulinate dehydratase: nucleotide sequence of a full-length cDNA clone.

PubMed ID: 3463993

DOI: 10.1073/pnas.83.20.7703

PubMed ID: 1678509

Title: RsaI polymorphism in the human delta-aminolevulinate dehydratase gene at 9q34.

PubMed ID: 1678509

DOI: 10.1093/nar/19.15.4307-a

PubMed ID: 1569184

Title: Cloning and expression of the defective genes from a patient with delta-aminolevulinate dehydratase porphyria.

PubMed ID: 1569184

DOI: 10.1172/jci115732

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 15164053

Title: DNA sequence and analysis of human chromosome 9.

PubMed ID: 15164053

DOI: 10.1038/nature02465

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 12665801

Title: Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides.

PubMed ID: 12665801

DOI: 10.1038/nbt810

PubMed ID: 3092810

Title: Identification of lysine at the active site of human 5-aminolevulinate dehydratase.

PubMed ID: 3092810

DOI: 10.1042/bj2360447

PubMed ID: 1769358

Title: The delta-aminolevulinate dehydratase polymorphism: higher blood lead levels in lead workers and environmentally exposed children with the 1-2 and 2-2 isozymes.

PubMed ID: 1769358

DOI: 10.1016/s0013-9351(05)80001-5

PubMed ID: 11032836

Title: The molecular mechanism of lead inhibition of human porphobilinogen synthase.

PubMed ID: 11032836

DOI: 10.1074/jbc.m007663200

PubMed ID: 17966070

Title: Association between delta-aminolevulinic acid dehydratase (ALAD) polymorphism and blood lead levels: a meta-regression analysis.

PubMed ID: 17966070

DOI: 10.1080/15287390701550946

PubMed ID: 19812033

Title: Allosteric inhibition of human porphobilinogen synthase.

PubMed ID: 19812033

DOI: 10.1074/jbc.m109.026294

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 12897770

Title: Control of tetrapyrrole biosynthesis by alternate quaternary forms of porphobilinogen synthase.

PubMed ID: 12897770

DOI: 10.1038/nsb963

PubMed ID: 1716854

Title: Molecular characterization of the human delta-aminolevulinate dehydratase 2 (ALAD2) allele: implications for molecular screening of individuals for genetic susceptibility to lead poisoning.

PubMed ID: 1716854

PubMed ID: 2063868

Title: Delta-aminolevulinate dehydratase deficient porphyria: identification of the molecular lesions in a severely affected homozygote.

PubMed ID: 2063868

PubMed ID: 1309003

Title: Cloning and expression of the defective genes in delta-aminolevulinate dehydratase porphyria: compound heterozygosity in this hereditary liver disease.

PubMed ID: 1309003

PubMed ID: 10519994

Title: A novel mutation of delta-aminolaevulinate dehydratase in a healthy child with 12% erythrocyte enzyme activity.

PubMed ID: 10519994

DOI: 10.1046/j.1365-2141.1999.01647.x

PubMed ID: 10706561

Title: Novel molecular defects of the delta-aminolevulinate dehydratase gene in a patient with inherited acute hepatic porphyria.

PubMed ID: 10706561

DOI: 10.1002/hep.510310321

PubMed ID: 16398658

Title: Dual gene defects involving delta-aminolaevulinate dehydratase and coproporphyrinogen oxidase in a porphyria patient.

PubMed ID: 16398658

DOI: 10.1111/j.1365-2141.2005.05852.x

PubMed ID: 17236137

Title: ALAD porphyria is a conformational disease.

PubMed ID: 17236137

DOI: 10.1086/511444

Sequence Information:

  • Length: 330
  • Mass: 36295
  • Checksum: E005F3055F6D9403
  • Sequence:
    • MQPQSVLHSG YFHPLLRAWQ TATTTLNASN LIYPIFVTDV PDDIQPITSL PGVARYGVKR 
LEEMLRPLVE EGLRCVLIFG VPSRVPKDER GSAADSEESP AIEAIHLLRK TFPNLLVACD 
VCLCPYTSHG HCGLLSENGA FRAEESRQRL AEVALAYAKA GCQVVAPSDM MDGRVEAIKE 
ALMAHGLGNR VSVMSYSAKF ASCFYGPFRD AAKSSPAFGD RRCYQLPPGA RGLALRAVDR 
DVREGADMLM VKPGMPYLDI VREVKDKHPD LPLAVYHVSG EFAMLWHGAQ AGAFDLKAAV 
LEAMTAFRRA GADIIITYYT PQLLQWLKEE

Genular Protein ID: 53946838

Symbol: Q6ZMU0_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q6ZMU0

Database IDs:

ARBA 8 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 1 CTD 1 ChEBI 13 DNASU 1 DisGeNET 1 EC 1 EMBL 2 GO 3 Gene3D 1 InterPro 3 KEGG 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PIRSF 1 PIRSR 3 PRINTS 1 PROSITE 1 PeptideAtlas 1 Pfam 1 REPRODUCTION-2DPAGE 1 RefSeq 3 Rhea 1 RuleBase 2 SAM 1 SMART 1 SUPFAM 1 UniPathway 1

Sequence Information:

  • Length: 359
  • Mass: 39050
  • Checksum: 4AD5E8C53B11BAED
  • Sequence:
    • MPPTSSTPSL SRPGLGQAGK PDTGSHPPPT ISTSIFLSCF PTIPLSRPRT TGPSHSYQSI 
SHPRSCRDVP DDIQPITSLP GVARYGVKRL EEMLRPLVEE GLRCVLIFGV PSRVPKDERG 
SAADSEESPA IEAIHLLRKT FPNLLVACDV CLCPYTSHGH CGLLSENGAF RAEESRQRLA 
EVALAYAKAG CQVVAPSDMM DGRVEAIKEA LMAHGLGNRV SVMSYSAKFA SCFYGPFRDA 
AKSSPAFGDR RCYQLPPGAR GLALRAVDRD VREGADMLMV KPGMLYLDIV REVKDKHPDL 
PLAVYHVSGE FAMLWHGAQA GAFDLKAAVL EAMTAFRRAG ADIIITYYTP QLLQWLKEE

Genular Protein ID: 523822687

Symbol: B7Z3I9_HUMAN

Name: N/A

UniProtKB Accession Codes:

B7Z3I9

Database IDs:

ARBA 8 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 1 CTD 1 ChEBI 13 DNASU 1 DisGeNET 1 EC 1 EMBL 2 GO 4 Gene3D 1 InterPro 3 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PIRSF 1 PIRSR 3 PRINTS 1 PROSITE 1 PeptideAtlas 1 Pfam 1 RefSeq 1 Rhea 1 RuleBase 2 SMART 1 SUPFAM 1 UniPathway 1

Sequence Information:

  • Length: 313
  • Mass: 34520
  • Checksum: EA8A783C37E9C899
  • Sequence:
    • MQPQSVLHSG YFHPLLRAWQ TATTTLNASN LIYPIFVTYG VKRLEEMLRP LVEEGLRCVL 
IFGVPSRVPK DERGSAADSE ESPAIEAIHL LRKTFPNLLV ACDVCLCPYT SHGHCGLLSE 
NGAFRAEESR QRLAEVALAY AKAGCQVVAP SDMMDGRVEA IKEALMAHGL GNRVSVMSYS 
AKFASCFYGP FRDAAKSSPA FGDRRCYQLP PGARGLALRA VDRDVREGAD MLMVKPGMPY 
LDIVREVKDK HPDLPLAVYH VSGEFAMLWH GAQAGAFDLK AAVLEAMTAF RRAGADIIIT 
YYTPQLLQWL KEE

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.