Genular: Defining Cellular Identity and Function

Details for: Tbl1x

Gene ID: 21372

Symbol: Tbl1x

Ensembl ID: ENSMUSG00000025246

Description: transducin (beta)-like 1 X-linked

Associated with

Cellular responses to stimuli
(R-MMU-8953897)
Cellular responses to stress
(R-MMU-2262752)
Cellular response to chemical stress
(R-MMU-9711123)
Chromatin modifying enzymes
(R-MMU-3247509)
Chromatin organization
(R-MMU-4839726)
Cytoprotection by hmox1
(R-MMU-9707564)
Gene expression (transcription)
(R-MMU-74160)
Generic transcription pathway
(R-MMU-212436)
Hdacs deacetylate histones
(R-MMU-3214815)
Metabolism
(R-MMU-1430728)
Metabolism of lipids
(R-MMU-556833)
Notch-hlh transcription pathway
(R-MMU-350054)
Nr1h2 and nr1h3-mediated signaling
(R-MMU-9024446)
Nr1h3 & nr1h2 regulate gene expression linked to cholesterol transport and efflux
(R-MMU-9029569)
Regulation of lipid metabolism by pparalpha
(R-MMU-400206)
Rna polymerase ii transcription
(R-MMU-73857)
Signaling by nuclear receptors
(R-MMU-9006931)
Signal transduction
(R-MMU-162582)
Chromatin binding
(GO:0003682)
Dna binding
(GO:0003677)
Fat cell differentiation
(GO:0045444)
Histone binding
(GO:0042393)
Histone deacetylase complex
(GO:0000118)
Identical protein binding
(GO:0042802)
Mitotic spindle
(GO:0072686)
Negative regulation of dna-templated transcription
(GO:0045892)
Nucleoplasm
(GO:0005654)
Nucleus
(GO:0005634)
Positive regulation of transcription by rna polymerase ii
(GO:0045944)
Proteasome-mediated ubiquitin-dependent protein catabolic process
(GO:0043161)
Protein binding
(GO:0005515)
Protein stabilization
(GO:0050821)
Regulation of transcription by rna polymerase ii
(GO:0006357)
Response to estrogen
(GO:0043627)
Response to steroid hormone
(GO:0048545)
Transcription cis-regulatory region binding
(GO:0000976)
Transcription corepressor activity
(GO:0003714)
Transcription regulator complex
(GO:0005667)
Transcription repressor complex
(GO:0017053)

Other Information

Proteins

F-box-like/WD repeat-containing protein TBL1X

Genular Protein ID: 1926333423

Symbol: TBL1X_MOUSE

Name: F-box-like/WD repeat-containing protein TBL1X

UniProtKB Accession Codes:

Q9QXE7 Q8BMM0 Q8BYQ4 Q8C0A1

Database IDs:

Citations:

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 10330347

Title: X-linked late-onset sensorineural deafness caused by a deletion involving OA1 and a novel gene containing WD-40 repeats.

PubMed ID: 10330347

DOI: 10.1086/302408

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 26070566

Title: Exchange factor TBL1 and arginine methyltransferase PRMT6 cooperate in protecting G protein pathway suppressor 2 (GPS2) from proteasomal degradation.

PubMed ID: 26070566

DOI: 10.1074/jbc.m115.637660

PubMed ID: 28348241

Title: Structure of the MeCP2-TBLR1 complex reveals a molecular basis for Rett syndrome and related disorders.

PubMed ID: 28348241

DOI: 10.1073/pnas.1700731114

Sequence Information:

Length: 527
Mass: 56802
Checksum: 146435A9C51DFDA6
Sequence:

MSITSDEVNF LVYRYLQESG FSHSAFTFGI ESHISQSNIN GTLVPPAALI SILQKGLQYV 
EAEISINEDG TVFDGRPIES LSLIDAVMPD VVQTRQQAFR EKLAQQQANA AAAAAAAAAT 
ATSTAATTPA AAAQQNPPKN GEATVNGEEN GAHAINNHSK PMEIDGDVEI PPSKATVLRG 
HESEVFICAW NPVSDLLASG SGDSTARIWN LNENSNGGST QLVLRHCIRE GGHDVPSNKD 
VTSLDWNSDG TLLATGSYDG FARIWTEDGN LASTLGQHKG PIFALKWNKK GNYILSAGVD 
KTTIIWDAHT GEAKQQFPFH SAPALDVDWQ NNTTFASCST DMCIHVCRLG CDRPVKTFQG 
HTNEVNAIKW DPSGMLLASC SDDMTLKIWS MKQDACVHDL QAHSKEIYTI KWSPTGPATS 
NPNSNIMLAS ASFDSTVRLW DVERGVCIHT LTKHQEPVYS VAFSPDGKYL ASGSFDKCVH 
IWNTQSGSLV HSYRGTGGIF EVCWNARGDK VGASASDGSV CVLDLRK

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Tbl1x

Associated with

Other Information

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

X-linked late-onset sensorineural deafness caused by a deletion involving OA1 and a novel gene containing WD-40 repeats. PubMed ID: 10330347

A tissue-specific atlas of mouse protein phosphorylation and expression. PubMed ID: 21183079

Exchange factor TBL1 and arginine methyltransferase PRMT6 cooperate in protecting G protein pathway suppressor 2 (GPS2) from proteasomal degradation. PubMed ID: 26070566