Genular: Defining Cellular Identity and Function

Details for: Tbr1

Gene ID: 21375

Symbol: Tbr1

Ensembl ID: ENSMUSG00000035033

Description: T-box brain transcription factor 1

Associated with

Amygdala development
(GO:0021764)
Cell fate specification
(GO:0001708)
Cerebral cortex development
(GO:0021987)
Chromatin
(GO:0000785)
Chromatin dna binding
(GO:0031490)
Chromatin remodeling
(GO:0006338)
Commitment of neuronal cell to specific neuron type in forebrain
(GO:0021902)
Conditioned taste aversion
(GO:0001661)
Dna-binding transcription factor activity
(GO:0003700)
Dna-binding transcription factor activity, rna polymerase ii-specific
(GO:0000981)
Dna binding
(GO:0003677)
Gene expression
(GO:0010467)
Hindbrain development
(GO:0030902)
Negative regulation of dna-templated transcription
(GO:0045892)
Neuron differentiation
(GO:0030182)
Nucleus
(GO:0005634)
Positive regulation of dna-templated transcription
(GO:0045893)
Positive regulation of transcription by rna polymerase ii
(GO:0045944)
Protein kinase binding
(GO:0019901)
Regulation of axon guidance
(GO:1902667)
Regulation of dna-templated transcription
(GO:0006355)
Regulation of gene expression
(GO:0010468)
Regulation of neuron projection development
(GO:0010975)
Regulation of transcription by rna polymerase ii
(GO:0006357)
Rna polymerase ii cis-regulatory region sequence-specific dna binding
(GO:0000978)
Specification of animal organ identity
(GO:0010092)

Other Information

Proteins

T-box brain protein 1

Genular Protein ID: 4043621099

Symbol: TBR1_MOUSE

Name: T-box brain protein 1

UniProtKB Accession Codes:

Q64336 Q7TSY9

Database IDs:

Citations:

PubMed ID: 7619531

Title: T-brain-1: a homolog of Brachyury whose expression defines molecularly distinct domains within the cerebral cortex.

PubMed ID: 7619531

DOI: 10.1016/0896-6273(95)90065-9

PubMed ID: 19468303

Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.

PubMed ID: 19468303

DOI: 10.1371/journal.pbio.1000112

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 9883721

Title: An olfactory sensory map develops in the absence of normal projection neurons or GABAergic interneurons.

PubMed ID: 9883721

DOI: 10.1016/s0896-6273(00)80647-9

PubMed ID: 11239428

Title: Tbr1 regulates differentiation of the preplate and layer 6.

PubMed ID: 11239428

DOI: 10.1016/s0896-6273(01)00211-2

PubMed ID: 15066269

Title: Transcriptional modification by a CASK-interacting nucleosome assembly protein.

PubMed ID: 15066269

DOI: 10.1016/s0896-6273(04)00139-4

PubMed ID: 16452087

Title: Comprehensive identification of phosphorylation sites in postsynaptic density preparations.

PubMed ID: 16452087

DOI: 10.1074/mcp.t500041-mcp200

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 21285371

Title: TBR1 directly represses Fezf2 to control the laminar origin and development of the corticospinal tract.

PubMed ID: 21285371

DOI: 10.1073/pnas.1016723108

Sequence Information:

Length: 681
Mass: 73940
Checksum: 6932EDE5412D97BF
Sequence:

MQLEHCLSPS IMLSKKFLNV SSSYPHSGGS ELVLHDHPII STTDNLERSS PLKKITRGMT 
NQSDTDNFPD SKDSPGDVQR SKLSPVLDGV SELRHSFDGS AADRYLLSQS SQPQSAATAP 
SAMFPYPSQH GPAHPAFSIG SPSRYMAHHP VITNGAYNSL LSNSSPQGYP TAGYPYPQQY 
GHSYQGAPFY QFSSTQPGLV PGKAQVYLCN RPLWLKFHRH QTEMIITKQG RRMFPFLSFN 
ISGLDPTAHY NIFVDVILAD PNHWRFQGGK WVPCGKADTN VQGNRVYMHP DSPNTGAHWM 
RQEISFGKLK LTNNKGASNN NGQMVVLQSL HKYQPRLHVV EVNEDGTEDT SQPGRVQTFT 
FPETQFIAVT AYQNTDITQL KIDHNPFAKG FRDNYDTIYT GCDMDRLTPS PNDSPRSQIV 
PGARYAMAGS FLQDQFVSNY AKARFHPGAG AGPGPGTDRS VPHTNGLLSP QQAEDPGAPS 
PQRWFVTPAN NRLDFAASAY DTATDFAGNA ATLLSYAAAG VKALPLQAAG CTGRPLGYYA 
DPSGWGARSP PQYCGAKSGS VLPCWPNSAA AAARMAGANP YLGEEAEGLA AERSPLAPAA 
EDAKPKDLSD SSWIETPSSI KSIDSSDSGI YEQAKRRRIS PADTPVSESS SPLKSEVLAQ 
RDCEKNCAKD IGGYYGFYSH S

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Tbr1

Associated with

Other Information

T-brain-1: a homolog of Brachyury whose expression defines molecularly distinct domains within the cerebral cortex. PubMed ID: 7619531

Lineage-specific biology revealed by a finished genome assembly of the mouse. PubMed ID: 19468303

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

An olfactory sensory map develops in the absence of normal projection neurons or GABAergic interneurons. PubMed ID: 9883721

Tbr1 regulates differentiation of the preplate and layer 6. PubMed ID: 11239428

Transcriptional modification by a CASK-interacting nucleosome assembly protein. PubMed ID: 15066269

Comprehensive identification of phosphorylation sites in postsynaptic density preparations. PubMed ID: 16452087

A tissue-specific atlas of mouse protein phosphorylation and expression. PubMed ID: 21183079

TBR1 directly represses Fezf2 to control the laminar origin and development of the corticospinal tract. PubMed ID: 21285371