Genular: Defining Cellular Identity and Function

Details for: Tbxas1

Gene ID: 21391

Symbol: Tbxas1

Ensembl ID: ENSMUSG00000029925

Description: thromboxane A synthase 1, platelet

Associated with

Arachidonic acid metabolism
(R-MMU-2142753)
Biological oxidations
(R-MMU-211859)
Cytochrome p450 - arranged by substrate type
(R-MMU-211897)
Eicosanoids
(R-MMU-211979)
Fatty acid metabolism
(R-MMU-8978868)
Metabolism
(R-MMU-1430728)
Metabolism of lipids
(R-MMU-556833)
Phase i - functionalization of compounds
(R-MMU-211945)
Synthesis of prostaglandins (pg) and thromboxanes (tx)
(R-MMU-2162123)
Cytosol
(GO:0005829)
Endoplasmic reticulum
(GO:0005783)
Endoplasmic reticulum membrane
(GO:0005789)
Fatty acid biosynthetic process
(GO:0006633)
Fatty acid metabolic process
(GO:0006631)
Heme binding
(GO:0020037)
Hydroperoxy icosatetraenoate dehydratase activity
(GO:0106256)
Icosanoid metabolic process
(GO:0006690)
Intracellular chloride ion homeostasis
(GO:0030644)
Iron ion binding
(GO:0005506)
Isomerase activity
(GO:0016853)
Lipid metabolic process
(GO:0006629)
Lyase activity
(GO:0016829)
Membrane
(GO:0016020)
Metal ion binding
(GO:0046872)
Monooxygenase activity
(GO:0004497)
Oxidoreductase activity
(GO:0016491)
Oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
(GO:0016705)
Positive regulation of vasoconstriction
(GO:0045907)
Prostaglandin biosynthetic process
(GO:0001516)
Prostaglandin metabolic process
(GO:0006693)
Thromboxane-a synthase activity
(GO:0004796)

Other Information

Proteins

Thromboxane-A synthase
Q3UTF0_MOUSE

Genular Protein ID: 346027182

Symbol: THAS_MOUSE

Name: Thromboxane-A synthase

UniProtKB Accession Codes:

P36423 P97505

Database IDs:

Citations:

PubMed ID: 7688225

Title: Molecular cloning and expression of murine thromboxane synthase.

PubMed ID: 7688225

DOI: 10.1006/bbrc.1993.1884

PubMed ID: 9367676

Title: Genomic organization, chromosomal localization, and expression of the murine thromboxane synthase gene.

PubMed ID: 9367676

DOI: 10.1006/geno.1997.4982

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 15010374

Title: TXAS-deleted mice exhibit normal thrombopoiesis, defective hemostasis, and resistance to arachidonate-induced death.

PubMed ID: 15010374

DOI: 10.1182/blood-2003-10-3661

Sequence Information:

Length: 533
Mass: 60391
Checksum: A06C3B53738E179A
Sequence:

MEVLGLLKFE VSGTIVTVTL LVALLALLKW YSMSAFSRLE KLGIRHPKPS PFVGNLMFFR 
QGFWESQLEL RERYGPLCGY YLGRRMHVVI SEPDMIKQVL VENFSNFSNR MASGLEPKMV 
ADSVLLLRDR RWEEVRGALM SSFSPEKLDE MTPLISQACE LLVAHLKRYA ASRDAFNIQR 
CYCCYTIDVV ASVAFGTQVD SQNSPEDPFV QHCRRASTFC IPRPLLVLIL SFPSIMVPLA 
RILPNKNRDE LNGFFNTLIR NVIALRDQQA AEERRRDFLQ MVLDAQHSMN SVGVEGFDMV 
PESLSSSECT KEPPQRCHPT STSKPFTVDE IVGQAFLFLI AGHEVITNTL SFITYLLATH 
PDCQERLLKE VDLFMGKHPA PEYHSLQEGL PYLDMVISET LRMYPPAFRF TREAAQDCEV 
LGQRIPAGTV LEIAVGALHH DPEHWPNPET FDPERFTAEA RLQRRPFTYL PFGAGPRSCL 
GVRLGLLVVK LTILQVLHKF RFEASPETQV PLQLESKSAL GPKNGVYIKI VSR

Genular Protein ID: 1634127872

Symbol: Q3UTF0_MOUSE

Name: N/A

UniProtKB Accession Codes:

Q3UTF0

Database IDs:

Citations:

PubMed ID: 10349636

Title: High-efficiency full-length cDNA cloning.

PubMed ID: 10349636

DOI: 10.1016/S0076-6879(99)03004-9

PubMed ID: 11042159

Title: Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes.

PubMed ID: 11042159

DOI: 10.1101/gr.145100

PubMed ID: 11076861

Title: RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer.

PubMed ID: 11076861

DOI: 10.1101/gr.152600

PubMed ID: 11217851

Title: Functional annotation of a full-length mouse cDNA collection.

PubMed ID: 11217851

DOI: 10.1038/35055500

PubMed ID: 12466851

Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.

PubMed ID: 12466851

DOI: 10.1038/nature01266

PubMed ID: 16141073

Title: Antisense Transcription in the Mammalian Transcriptome.

PubMed ID: 16141073

DOI: 10.1126/science.1112009

Sequence Information:

Length: 455
Mass: 51700
Checksum: 317CF3216E2CD34B
Sequence:

MEVLGLLKFE VSGTIVTVTL LVALLALLKW YSMSAFSRLE KLGIRHPKPS PFVGNLMFFR 
QGFWESQLEL RERYGPLCGY YLGRRMHVVI SEPDMIKQVL VENFSNFSNR MASGLEPKMV 
ADSVLLLRDR RWEEVRGALM SSFSPEKLDE MTPLISQACE LLVAHLKRYA ASRDAFNIQR 
CYCCYTIDVV ASVAFGTQVD SQNSPEDPFV QHCRRASTFC IPRPLLVLIL SFPSIMVPLA 
RILPNKNRDE LNGFFNTLIR NVIALRDQQA AEERRRDFLQ MVLDAQHSMN SVGVEGFDMV 
PESLSSSECT KEPPQRCHPT STSKPFTVDE IVGQAFLFLI AGHEVITNTL SFITYLLATH 
PDCQERLLKE VDLFMGKHPA PEYHSLQEGL PYLDMVISET LRMYPPAFRF TREAAQDCEV 
LGQRIPAGTV LEIAVGALHH DPEHWPNPET FDPER

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Tbxas1

Associated with

Other Information

Molecular cloning and expression of murine thromboxane synthase. PubMed ID: 7688225

Genomic organization, chromosomal localization, and expression of the murine thromboxane synthase gene. PubMed ID: 9367676

A tissue-specific atlas of mouse protein phosphorylation and expression. PubMed ID: 21183079

TXAS-deleted mice exhibit normal thrombopoiesis, defective hemostasis, and resistance to arachidonate-induced death. PubMed ID: 15010374

High-efficiency full-length cDNA cloning. PubMed ID: 10349636

Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes. PubMed ID: 11042159

RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer. PubMed ID: 11076861

Functional annotation of a full-length mouse cDNA collection. PubMed ID: 11217851

Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. PubMed ID: 12466851

Antisense Transcription in the Mammalian Transcriptome. PubMed ID: 16141073