Details for: ALCAM

Gene ID: 214

Symbol: ALCAM

Ensembl ID: ENSG00000170017

Description: activated leukocyte cell adhesion molecule

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 479.0247
    Cell Significance Index: -74.5100
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 283.7843
    Cell Significance Index: -71.9800
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 148.6005
    Cell Significance Index: -60.3700
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 63.0641
    Cell Significance Index: -60.2100
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 60.4401
    Cell Significance Index: -74.5200
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 27.6774
    Cell Significance Index: -85.0100
  • Cell Name: sebaceous gland cell (CL2000021)
    Fold Change: 12.9539
    Cell Significance Index: 16.7600
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 11.8433
    Cell Significance Index: -25.9200
  • Cell Name: leptomeningeal cell (CL0000708)
    Fold Change: 6.7433
    Cell Significance Index: 144.1400
  • Cell Name: luminal hormone-sensing cell of mammary gland (CL4033058)
    Fold Change: 5.1323
    Cell Significance Index: 31.5900
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: 3.1947
    Cell Significance Index: 141.3100
  • Cell Name: peg cell (CL4033014)
    Fold Change: 3.1701
    Cell Significance Index: 73.2400
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: 3.0290
    Cell Significance Index: 114.7000
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 2.4242
    Cell Significance Index: 481.0900
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 2.3647
    Cell Significance Index: 848.1900
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: 2.0327
    Cell Significance Index: 136.6800
  • Cell Name: umbrella cell of urothelium (CL4030056)
    Fold Change: 1.8770
    Cell Significance Index: 17.2900
  • Cell Name: centrilobular region hepatocyte (CL0019029)
    Fold Change: 1.8394
    Cell Significance Index: 30.9900
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 1.6709
    Cell Significance Index: 271.7600
  • Cell Name: corneal endothelial cell (CL0000132)
    Fold Change: 1.4145
    Cell Significance Index: 21.5200
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 1.3535
    Cell Significance Index: 271.5100
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 1.1807
    Cell Significance Index: 644.8000
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 1.1261
    Cell Significance Index: 778.8500
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.7970
    Cell Significance Index: 143.6700
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.7407
    Cell Significance Index: 668.7700
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.7379
    Cell Significance Index: 80.2600
  • Cell Name: interstitial cell of ovary (CL0002094)
    Fold Change: 0.5997
    Cell Significance Index: 7.6800
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.5943
    Cell Significance Index: 73.0800
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: 0.5768
    Cell Significance Index: 42.9900
  • Cell Name: epithelial cell of sweat gland (CL1000448)
    Fold Change: 0.5597
    Cell Significance Index: 0.4000
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 0.4249
    Cell Significance Index: 19.8100
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: 0.3808
    Cell Significance Index: 23.4100
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 0.3231
    Cell Significance Index: 205.1800
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: 0.3157
    Cell Significance Index: 143.2800
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.3091
    Cell Significance Index: 8.9100
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: 0.2215
    Cell Significance Index: 37.8200
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 0.2128
    Cell Significance Index: 4.6100
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.1823
    Cell Significance Index: 12.6100
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.1443
    Cell Significance Index: 271.7500
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.0944
    Cell Significance Index: 41.7200
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.0360
    Cell Significance Index: 66.3600
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.0135
    Cell Significance Index: -20.8300
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: -0.0159
    Cell Significance Index: -0.5600
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0161
    Cell Significance Index: -10.0300
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0370
    Cell Significance Index: -27.4400
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0381
    Cell Significance Index: -28.8400
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0586
    Cell Significance Index: -42.9900
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0591
    Cell Significance Index: -80.3400
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: -0.0610
    Cell Significance Index: -3.1700
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: -0.0766
    Cell Significance Index: -7.5800
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0871
    Cell Significance Index: -49.1100
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.1293
    Cell Significance Index: -13.2100
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: -0.1430
    Cell Significance Index: -27.2200
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.1599
    Cell Significance Index: -20.6600
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.1705
    Cell Significance Index: -35.9200
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.1750
    Cell Significance Index: -8.2300
  • Cell Name: pancreatic endocrine cell (CL0008024)
    Fold Change: -0.1802
    Cell Significance Index: -20.5700
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: -0.1984
    Cell Significance Index: -27.2400
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: -0.2185
    Cell Significance Index: -6.1100
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.2208
    Cell Significance Index: -63.5400
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: -0.2218
    Cell Significance Index: -26.1600
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.2404
    Cell Significance Index: -34.9400
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: -0.3051
    Cell Significance Index: -8.1800
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.3441
    Cell Significance Index: -40.1100
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: -0.4014
    Cell Significance Index: -28.3900
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: -0.4361
    Cell Significance Index: -5.9500
  • Cell Name: periportal region hepatocyte (CL0019026)
    Fold Change: -0.4560
    Cell Significance Index: -6.7300
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.5200
    Cell Significance Index: -59.5700
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.5611
    Cell Significance Index: -58.4200
  • Cell Name: hippocampal astrocyte (CL0002604)
    Fold Change: -0.5771
    Cell Significance Index: -8.0700
  • Cell Name: fallopian tube secretory epithelial cell (CL4030006)
    Fold Change: -0.5940
    Cell Significance Index: -9.1900
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: -0.6074
    Cell Significance Index: -27.5300
  • Cell Name: odontoblast (CL0000060)
    Fold Change: -0.6356
    Cell Significance Index: -81.4800
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.6390
    Cell Significance Index: -35.8600
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: -0.6919
    Cell Significance Index: -36.0400
  • Cell Name: cortical interneuron (CL0008031)
    Fold Change: -0.7043
    Cell Significance Index: -16.8900
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -0.7106
    Cell Significance Index: -54.5300
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.7771
    Cell Significance Index: -24.8900
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.8158
    Cell Significance Index: -64.6100
  • Cell Name: epithelial cell of prostate (CL0002231)
    Fold Change: -0.8420
    Cell Significance Index: -5.1900
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.8521
    Cell Significance Index: -52.2400
  • Cell Name: hippocampal interneuron (CL1001569)
    Fold Change: -0.8683
    Cell Significance Index: -11.2600
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: -0.8832
    Cell Significance Index: -18.8100
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: -0.9283
    Cell Significance Index: -59.8900
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: -1.0066
    Cell Significance Index: -26.9300
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: -1.1257
    Cell Significance Index: -32.2700
  • Cell Name: oligodendrocyte (CL0000128)
    Fold Change: -1.2806
    Cell Significance Index: -13.7300
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -1.2976
    Cell Significance Index: -42.4900
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: -1.3555
    Cell Significance Index: -28.7700
  • Cell Name: luminal cell of prostate epithelium (CL0002340)
    Fold Change: -1.4137
    Cell Significance Index: -14.6300
  • Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
    Fold Change: -1.4177
    Cell Significance Index: -35.3700
  • Cell Name: VIP GABAergic cortical interneuron (CL4023016)
    Fold Change: -1.4385
    Cell Significance Index: -28.8800
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: -1.4511
    Cell Significance Index: -41.4100
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: -1.4596
    Cell Significance Index: -28.8600
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -1.4921
    Cell Significance Index: -78.3400
  • Cell Name: astrocyte of the cerebral cortex (CL0002605)
    Fold Change: -1.5436
    Cell Significance Index: -26.6900
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: -1.5563
    Cell Significance Index: -42.3600
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: -1.5946
    Cell Significance Index: -41.9300
  • Cell Name: stratified epithelial cell (CL0000079)
    Fold Change: -1.6138
    Cell Significance Index: -59.2400
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -1.6454
    Cell Significance Index: -57.6400

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** ALCAM is a member of the immunoglobulin superfamily and is characterized by its ability to bind to other molecules, promoting cell-cell interactions and adhesion. It is primarily expressed on the surface of cells in the immune system, including T cells, granule cells, and epithelial cells of the lower respiratory tract. ALCAM has also been found in the nervous system, where it is involved in axon guidance and neuronal development. **Pathways and Functions:** ALCAM is involved in various signaling pathways, including: 1. **Adaptive Immune Response:** ALCAM plays a crucial role in the activation and regulation of T cells, facilitating their interaction with antigen-presenting cells and promoting the adaptive immune response. 2. **Cell Adhesion:** ALCAM mediates cell-cell adhesion by binding to other molecules, such as integrins and selectins, which are essential for the migration and homing of immune cells. 3. **Neuronal Development:** ALCAM is involved in the development and guidance of axons in the nervous system, influencing the formation of neural connections and the establishment of neuronal territories. 4. **Signal Transduction:** ALCAM can initiate signal transduction cascades, influencing various cellular processes, including cell growth, differentiation, and survival. **Clinical Significance:** The dysregulation of ALCAM has been implicated in various diseases, including: 1. **Autoimmune Disorders:** ALCAM has been found to be overexpressed in autoimmune diseases, such as multiple sclerosis and rheumatoid arthritis, suggesting its role in immune system dysregulation. 2. **Cancer:** ALCAM has been associated with cancer progression and metastasis, particularly in epithelial cancers, where it promotes cell-cell adhesion and migration. 3. **Neurological Disorders:** ALCAM has been implicated in neurological disorders, such as Alzheimer's disease and Parkinson's disease, where it may contribute to axonal degeneration and neuronal loss. In conclusion, ALCAM is a multifunctional protein that plays a crucial role in various biological processes, including immune response, neuronal development, and cell adhesion. Its dysregulation has been implicated in various diseases, highlighting the need for further research into the mechanisms of ALCAM and its potential therapeutic applications.

Genular Protein ID: 2116669436

Symbol: CD166_HUMAN

Name: CD166 antigen

UniProtKB Accession Codes:

Q13740 B2RNS3 B4DTU0 O60892 Q1HGM8 Q1HGM9 Q6PEY4 Q6ZS95

Database IDs:

ABCD 1 AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 2 CDD 1 CPTAC 2 CPTC 1 CTD 1 ChEMBL 1 ChiTaRS 1 DIP 1 DMDM 1 DNASU 1 DisGeNET 1 DisProt 1 EMBL 14 Ensembl 2 EvolutionaryTrace 1 ExpressionAtlas 1 GO 18 Gene3D 1 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyConnect 1 GlyCosmos 1 GlyGen 1 HGNC 1 HPA 1 InParanoid 1 IntAct 1 InterPro 8 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MassIVE 1 MetOSite 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 1 PDBsum 1 PIR 1 PRO 1 PROSITE 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 2 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 4 Pumba 1 RNAct 1 Reactome 1 RefSeq 3 SIGNOR 1 SMART 3 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 SwissPalm 1 TCDB 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 7760007

Title: Cloning, mapping, and characterization of activated leukocyte-cell adhesion molecule (ALCAM), a CD6 ligand.

PubMed ID: 7760007

DOI: 10.1084/jem.181.6.2213

PubMed ID: 15496415

Title: Molecular isolation and characterization of a soluble isoform of activated leukocyte cell adhesion molecule that modulates endothelial cell function.

PubMed ID: 15496415

DOI: 10.1074/jbc.m407776200

PubMed ID: 16641997

Title: The DNA sequence, annotation and analysis of human chromosome 3.

PubMed ID: 16641997

DOI: 10.1038/nature04728

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 9502422

Title: MEMD, a new cell adhesion molecule in metastasizing human melanoma cell lines, is identical to ALCAM (activated leukocyte cell adhesion molecule).

PubMed ID: 9502422

PubMed ID: 8823162

Title: Recognition of diverse proteins by members of the immunoglobulin superfamily: delineation of the receptor binding site in the human CD6 ligand ALCAM.

PubMed ID: 8823162

DOI: 10.1021/bi961038k

PubMed ID: 12754519

Title: Identification and quantification of N-linked glycoproteins using hydrazide chemistry, stable isotope labeling and mass spectrometry.

PubMed ID: 12754519

DOI: 10.1038/nbt827

PubMed ID: 15048703

Title: Frontline: Optimal T cell activation requires the engagement of CD6 and CD166.

PubMed ID: 15048703

DOI: 10.1002/eji.200424856

PubMed ID: 15294938

Title: Relevance of CD6-mediated interactions in T cell activation and proliferation.

PubMed ID: 15294938

DOI: 10.4049/jimmunol.173.4.2262

PubMed ID: 16335952

Title: Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry.

PubMed ID: 16335952

DOI: 10.1021/pr0502065

PubMed ID: 16352806

Title: Long-term engagement of CD6 and ALCAM is essential for T-cell proliferation induced by dendritic cells.

PubMed ID: 16352806

DOI: 10.1182/blood-2005-09-3881

PubMed ID: 16914752

Title: CD6 regulates T-cell responses through activation-dependent recruitment of the positive regulator SLP-76.

PubMed ID: 16914752

DOI: 10.1128/mcb.00688-06

PubMed ID: 19159218

Title: Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry.

PubMed ID: 19159218

DOI: 10.1021/pr8008012

PubMed ID: 19349973

Title: Mass-spectrometric identification and relative quantification of N-linked cell surface glycoproteins.

PubMed ID: 19349973

DOI: 10.1038/nbt.1532

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 23169771

Title: Novel role for ALCAM in lymphatic network formation and function.

PubMed ID: 23169771

DOI: 10.1096/fj.12-217844

PubMed ID: 24740813

Title: CD166 regulates human and murine hematopoietic stem cells and the hematopoietic niche.

PubMed ID: 24740813

DOI: 10.1182/blood-2014-03-565721

PubMed ID: 24945728

Title: Modulation of CD6 function through interaction with galectin-1 and -3.

PubMed ID: 24945728

DOI: 10.1016/j.febslet.2014.05.064

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 25944712

Title: N-terminome analysis of the human mitochondrial proteome.

PubMed ID: 25944712

DOI: 10.1002/pmic.201400617

PubMed ID: 29263213

Title: ILT3.Fc-CD166 Interaction Induces Inactivation of p70 S6 Kinase and Inhibits Tumor Cell Growth.

PubMed ID: 29263213

DOI: 10.4049/jimmunol.1700553

PubMed ID: 8520490

Title: Molecular model of the N-terminal receptor-binding domain of the human CD6 ligand ALCAM.

PubMed ID: 8520490

DOI: 10.1002/pro.5560040822

PubMed ID: 26146185

Title: Structures of CD6 and its ligand CD166 give insight into their interaction.

PubMed ID: 26146185

DOI: 10.1016/j.str.2015.05.019

Sequence Information:

  • Length: 583
  • Mass: 65102
  • Checksum: 68FEFD67C14B0C57
  • Sequence:
    • MESKGASSCR LLFCLLISAT VFRPGLGWYT VNSAYGDTII IPCRLDVPQN LMFGKWKYEK 
PDGSPVFIAF RSSTKKSVQY DDVPEYKDRL NLSENYTLSI SNARISDEKR FVCMLVTEDN 
VFEAPTIVKV FKQPSKPEIV SKALFLETEQ LKKLGDCISE DSYPDGNITW YRNGKVLHPL 
EGAVVIIFKK EMDPVTQLYT MTSTLEYKTT KADIQMPFTC SVTYYGPSGQ KTIHSEQAVF 
DIYYPTEQVT IQVLPPKNAI KEGDNITLKC LGNGNPPPEE FLFYLPGQPE GIRSSNTYTL 
TDVRRNATGD YKCSLIDKKS MIASTAITVH YLDLSLNPSG EVTRQIGDAL PVSCTISASR 
NATVVWMKDN IRLRSSPSFS SLHYQDAGNY VCETALQEVE GLKKRESLTL IVEGKPQIKM 
TKKTDPSGLS KTIICHVEGF PKPAIQWTIT GSGSVINQTE ESPYINGRYY SKIIISPEEN 
VTLTCTAENQ LERTVNSLNV SAISIPEHDE ADEISDENRE KVNDQAKLIV GIVVGLLLAA 
LVAGVVYWLY MKKSKTASKH VNKDLGNMEE NKKLEENNHK TEA

Genular Protein ID: 1452217731

Symbol: B3KNN9_HUMAN

Name: N/A

UniProtKB Accession Codes:

B3KNN9

Database IDs:

ARBA 7 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 1 CTD 1 DNASU 1 DisGeNET 1 EMBL 2 GO 4 Gene3D 1 InterPro 7 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 2 PeptideAtlas 1 Pfam 2 RefSeq 1 SAM 2 SMART 2 SUPFAM 1

Citations:

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

Sequence Information:

  • Length: 555
  • Mass: 61941
  • Checksum: D2323DF06D268153
  • Sequence:
    • MESKGASSCR LLFCLLISAT VFRPGLGWYT VNSAYGDTII IPCRLDVPQN LMFGKWKYEK 
PDGSPVFIAF RSSTKKSVQY DDVPEYKDRL NLSENYTLSI SNARISDEKR FVCMLVTEDN 
VFEAPTIVKV FKQPSKPEIV SKALFLETEQ LKKLGDCISE DSYPDGNITW YRNGKVLHPL 
EGAVVIIFKK EMDPVTQLYT MTSTLEYKTT KADIQMPFTC SVTYYGPSGQ KTIHSEQAVF 
DIYYPTEQVT IQVLPPKNAI KEGDNITLKC LGNGNPPPEE FLFYLPGQPE GIRSSNTYTL 
MDVRRNATGD YKCSLIDKKS MIASTAITVH YLDLSLNPSG EVTRQIGDAL PVSCTISASR 
NATVVWMKDN IRLRSSPSFS SLHYQDAGNY VCETALQEVE GLKKRESLTL IVEGKPQIKM 
TKKTDPSGLS KTIICHVEGF PKPAIQWTIT GSGSVINQTE ESPYINGRYY SKIIISPEEN 
VTLTCTAENQ LERTVNSLNV SAISIPEHDE ADEISDENRE KVNDQAKLIV GIVVGLLLAA 
LVAGVVYWLY MKKSK

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.