Genular: Defining Cellular Identity and Function

Details for: Tcf21

Gene ID: 21412

Symbol: Tcf21

Ensembl ID: ENSMUSG00000045680

Description: transcription factor 21

Associated with

Animal organ morphogenesis
(GO:0009887)
Bhlh transcription factor binding
(GO:0043425)
Branching involved in ureteric bud morphogenesis
(GO:0001658)
Branchiomeric skeletal muscle development
(GO:0014707)
Bronchiole development
(GO:0060435)
Developmental process
(GO:0032502)
Diaphragm development
(GO:0060539)
Dna-binding transcription activator activity, rna polymerase ii-specific
(GO:0001228)
Dna-binding transcription factor activity, rna polymerase ii-specific
(GO:0000981)
Dna-binding transcription repressor activity, rna polymerase ii-specific
(GO:0001227)
Dna binding
(GO:0003677)
E-box binding
(GO:0070888)
Embryonic digestive tract morphogenesis
(GO:0048557)
Epithelial cell differentiation
(GO:0030855)
Gland development
(GO:0048732)
Glomerulus development
(GO:0032835)
Histone deacetylase binding
(GO:0042826)
Kidney development
(GO:0001822)
Lung alveolus development
(GO:0048286)
Lung morphogenesis
(GO:0060425)
Lung vasculature development
(GO:0060426)
Metanephric glomerular capillary formation
(GO:0072277)
Metanephric mesenchymal cell differentiation
(GO:0072162)
Morphogenesis of a branching structure
(GO:0001763)
Negative regulation of androgen receptor signaling pathway
(GO:0060766)
Negative regulation of transcription by rna polymerase ii
(GO:0000122)
Nuclear androgen receptor binding
(GO:0050681)
Nucleoplasm
(GO:0005654)
Nucleus
(GO:0005634)
Positive regulation of transcription by rna polymerase ii
(GO:0045944)
Protein binding
(GO:0005515)
Protein dimerization activity
(GO:0046983)
Regulation of transcription by rna polymerase ii
(GO:0006357)
Reproductive structure development
(GO:0048608)
Respiratory system development
(GO:0060541)
Rna polymerase ii transcription regulatory region sequence-specific dna binding
(GO:0000977)
Roof of mouth development
(GO:0060021)
Sequence-specific double-stranded dna binding
(GO:1990837)
Sertoli cell differentiation
(GO:0060008)
Sex determination
(GO:0007530)
Sex differentiation
(GO:0007548)
Spleen development
(GO:0048536)
Transcription regulator complex
(GO:0005667)
Ureteric bud development
(GO:0001657)
Vasculature development
(GO:0001944)

Other Information

Proteins

Transcription factor 21

Genular Protein ID: 2705737611

Symbol: TCF21_MOUSE

Name: Transcription factor 21

UniProtKB Accession Codes:

O35437 Q3U023

Database IDs:

Citations:

PubMed ID: 9545526

Title: Cloning of capsulin, a basic helix-loop-helix factor expressed in progenitor cells of the pericardium and the coronary arteries.

PubMed ID: 9545526

DOI: 10.1016/s0925-4773(98)00031-8

PubMed ID: 9733105

Title: Epicardin: a novel basic helix-loop-helix transcription factor gene expressed in epicardium, branchial arch myoblasts, and mesenchyme of developing lung, gut, kidney, and gonads.

PubMed ID: 9733105

DOI: 10.1002/(sici)1097-0177(199809)213:1<105::aid-aja10>3.0.co;2-1

PubMed ID: 9545521

Title: Capsulin: a novel bHLH transcription factor expressed in epicardial progenitors and mesenchyme of visceral organs.

PubMed ID: 9545521

DOI: 10.1016/s0925-4773(98)00030-6

PubMed ID: 10572052

Title: The basic-helix-loop-helix protein pod1 is critically important for kidney and lung organogenesis.

PubMed ID: 10572052

DOI: 10.1242/dev.126.24.5771

PubMed ID: 11287187

Title: Pod-1/Capsulin shows a sex- and stage-dependent expression pattern in the mouse gonad development and represses expression of Ad4BP/SF-1.

PubMed ID: 11287187

DOI: 10.1016/s0925-4773(01)00298-2

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 10944221

Title: The basic helix-loop-helix transcription factor capsulin controls spleen organogenesis.

PubMed ID: 10944221

DOI: 10.1073/pnas.97.17.9525

Sequence Information:

Length: 179
Mass: 19681
Checksum: 7BA3892818DB355F
Sequence:

MSTGSLSDVE DLQEVEMLDC DSLKVDSNKE FGTSNESTEE GSNCENGSPQ KGRGGLGKRR 
KAPTKKSPLS GVSQEGKQVQ RNAANARERA RMRVLSKAFS RLKTTLPWVP PDTKLSKLDT 
LRLASSYIAH LRQILANDKY ENGYIHPVNL TWPFMVAGKP ENDLKEVVTA NRLCGTTAS

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Tcf21

Associated with

Other Information

Cloning of capsulin, a basic helix-loop-helix factor expressed in progenitor cells of the pericardium and the coronary arteries. PubMed ID: 9545526

Epicardin: a novel basic helix-loop-helix transcription factor gene expressed in epicardium, branchial arch myoblasts, and mesenchyme of developing lung, gut, kidney, and gonads. PubMed ID: 9733105

Capsulin: a novel bHLH transcription factor expressed in epicardial progenitors and mesenchyme of visceral organs. PubMed ID: 9545521

The basic-helix-loop-helix protein pod1 is critically important for kidney and lung organogenesis. PubMed ID: 10572052

Pod-1/Capsulin shows a sex- and stage-dependent expression pattern in the mouse gonad development and represses expression of Ad4BP/SF-1. PubMed ID: 11287187

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

The basic helix-loop-helix transcription factor capsulin controls spleen organogenesis. PubMed ID: 10944221