Details for: Tfap2c

Gene ID: 21420

Symbol: Tfap2c

Ensembl ID: ENSMUSG00000028640

Description: transcription factor AP-2, gamma

Associated with

  • Activation of the tfap2 (ap-2) family of transcription factors
    (R-MMU-8866907)
  • Developmental biology
    (R-MMU-1266738)
  • Gastrulation
    (R-MMU-9758941)
  • Gene expression (transcription)
    (R-MMU-74160)
  • Generic transcription pathway
    (R-MMU-212436)
  • Metabolism of proteins
    (R-MMU-392499)
  • Negative regulation of activity of tfap2 (ap-2) family transcription factors
    (R-MMU-8866904)
  • Post-translational protein modification
    (R-MMU-597592)
  • Rna polymerase ii transcription
    (R-MMU-73857)
  • Specification of the neural plate border
    (R-MMU-9834899)
  • Sumo e3 ligases sumoylate target proteins
    (R-MMU-3108232)
  • Sumoylation
    (R-MMU-2990846)
  • Sumoylation of transcription factors
    (R-MMU-3232118)
  • Tfap2 (ap-2) family regulates transcription of cell cycle factors
    (R-MMU-8866911)
  • Transcriptional regulation by the ap-2 (tfap2) family of transcription factors
    (R-MMU-8864260)
  • Anatomical structure development
    (GO:0048856)
  • Cerebral cortex development
    (GO:0021987)
  • Dichotomous subdivision of terminal units involved in mammary gland duct morphogenesis
    (GO:0060598)
  • Dna-binding transcription activator activity, rna polymerase ii-specific
    (GO:0001228)
  • Dna-binding transcription factor activity
    (GO:0003700)
  • Dna-binding transcription factor activity, rna polymerase ii-specific
    (GO:0000981)
  • Dna-binding transcription repressor activity, rna polymerase ii-specific
    (GO:0001227)
  • Dna binding
    (GO:0003677)
  • Epithelial cell differentiation
    (GO:0030855)
  • Epithelial cell proliferation involved in mammary gland duct elongation
    (GO:0060750)
  • Forebrain neuron fate commitment
    (GO:0021877)
  • Germ-line stem cell population maintenance
    (GO:0030718)
  • Hair follicle development
    (GO:0001942)
  • Keratinocyte development
    (GO:0003334)
  • Mitochondrion
    (GO:0005739)
  • Negative regulation of gene expression, epigenetic
    (GO:0045814)
  • Nucleoplasm
    (GO:0005654)
  • Nucleus
    (GO:0005634)
  • Positive regulation of transcription by rna polymerase ii
    (GO:0045944)
  • Protein binding
    (GO:0005515)
  • Regulation of cell population proliferation
    (GO:0042127)
  • Regulation of dna-templated transcription
    (GO:0006355)
  • Regulation of epidermis development
    (GO:0045682)
  • Regulation of transcription by rna polymerase ii
    (GO:0006357)
  • Rna polymerase ii cis-regulatory region sequence-specific dna binding
    (GO:0000978)
  • Rna polymerase ii transcription regulatory region sequence-specific dna binding
    (GO:0000977)
  • Sebaceous gland development
    (GO:0048733)
  • Sequence-specific double-stranded dna binding
    (GO:1990837)
  • Skin development
    (GO:0043588)
  • Somatic stem cell population maintenance
    (GO:0035019)
  • Stem cell differentiation
    (GO:0048863)
  • Stem cell population maintenance
    (GO:0019827)
  • Transcription by rna polymerase ii
    (GO:0006366)
  • Trophectodermal cell differentiation
    (GO:0001829)

Other Information

Genular Protein ID: 2961284

Symbol: AP2C_MOUSE

Name: Transcription factor AP-2 gamma

UniProtKB Accession Codes:

Q61312 Q99L72

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 CCDS 1 CTD 1 ChiTaRS 1 DNASU 1 EMBL 5 Ensembl 1 ExpressionAtlas 1 GO 33 GeneTree 1 Genevisible 1 HOGENOM 1 InParanoid 1 InterPro 3 KEGG 1 MGI 1 MaxQB 1 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 PRINTS 2 PRO 1 PaxDb 1 Pfam 1 PhosphoSitePlus 1 Proteomes 1 ProteomicsDB 1 RNAct 1 Reactome 4 RefSeq 2 SAM 1 SMR 1 STRING 1 TreeFam 1 UCSC 1 UniProtKB 1 VEuPathDB 1 eggNOG 1 iPTMnet 1

Citations:

PubMed ID: 8660922

Title: AP-2.2: a novel AP-2-related transcription factor induced by retinoic acid during differentiation of P19 embryonal carcinoma cells.

PubMed ID: 8660922

DOI: 10.1006/excr.1996.0184

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 19468303

Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.

PubMed ID: 19468303

DOI: 10.1371/journal.pbio.1000112

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 12504852

Title: Cloning of mouse Cited4, a member of the CITED family p300/CBP-binding transcriptional coactivators: induced expression in mammary epithelial cells.

PubMed ID: 12504852

DOI: 10.1006/geno.2002.7005

Sequence Information:

  • Length: 449
  • Mass: 49137
  • Checksum: 92490E234697B6A3
  • Sequence:
    • MLWKITDNVK YEEDCEDRHD SSSNGNPRIP HLSSPGQHLY SPAPPLSHTG VAEYQPPPYF 
PPPYQQLAYS QSADHYSHLG EAYAAAMNPL HQPAATGSQQ QAWPGRQSQE GSSLASHHSR 
SASLIPHISG LEGGSVSARR EVYRRSDLLL PHAHALEAGL AENLGLHEMA HPIEEVQNVD 
DAHLLLHDQT VIRKGPISMT KNPLGLPCQK DLVGVVMNPS EVFCSVPGRL SLLSSTSKYK 
VTVAEVQRRL SPPECLNASL LGGVLRRAKS KNGGRSLREK LDKIGLNLPA GRRKAAHVTL 
LTSLVEGEAV HLARDFAYVC EAEFPSKAVA DYLTRPHLGG RNEMATRKSM LLAAQQVCKE 
FTDLLHQDRT PNGNNRPAQV LEPNIQNCLS HFSLITHGFG SQAICAAVSA VQNYIKEALI 
AIDKSYMNPG DQSPADSSKT MEKMEKHRK

Genular Protein ID: 467188425

Symbol: Q3ULB3_MOUSE

Name: N/A

UniProtKB Accession Codes:

Q3ULB3

Database IDs:

AGR 1 ARBA 1 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CTD 1 ChiTaRS 1 DNASU 1 EMBL 2 Ensembl 2 ExpressionAtlas 1 GO 4 GeneTree 1 InterPro 3 KEGG 1 MGI 2 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PRINTS 2 PeptideAtlas 1 Pfam 2 Proteomes 2 ProteomicsDB 1 RefSeq 2 SAM 1 SMR 1 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 10349636

Title: High-efficiency full-length cDNA cloning.

PubMed ID: 10349636

DOI: 10.1016/S0076-6879(99)03004-9

PubMed ID: 11042159

Title: Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes.

PubMed ID: 11042159

DOI: 10.1101/gr.145100

PubMed ID: 11076861

Title: RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer.

PubMed ID: 11076861

DOI: 10.1101/gr.152600

PubMed ID: 11217851

Title: Functional annotation of a full-length mouse cDNA collection.

PubMed ID: 11217851

DOI: 10.1038/35055500

PubMed ID: 12466851

Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.

PubMed ID: 12466851

DOI: 10.1038/nature01266

PubMed ID: 16141073

Title: Antisense Transcription in the Mammalian Transcriptome.

PubMed ID: 16141073

DOI: 10.1126/science.1112009

PubMed ID: 19468303

Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.

PubMed ID: 19468303

DOI: 10.1371/journal.pbio.1000112

Sequence Information:

  • Length: 488
  • Mass: 52832
  • Checksum: F335358228EEA852
  • Sequence:
    • MGGGLLNEGA VRRGRRTPNP WGTGNRTVAR NALLAPPSDA AREPSPEGSK DSSPQDRHDS 
SSNGNPRIPH LSSPGQHLYS PAPPLSHTGV AEYQPPPYFP PPYQQLAYSQ SADHYSHLGE 
AYAAAMNPLH QPAATGSQQQ AWPGRQSQEG SSLASHHSRS ASLIPHISGL EGGSVSARRE 
VYRRSDLLLP HAHALEAGLA ENLGLHEMAH PIEEVQNVDD AHLLLHDQTV IRKGPISMTK 
NPLGLPCQKD LVGVVMNPSE VFCSVPGRLS LLSSTSKYKV TVAEVQRRLS PPECLNASLL 
GGVLRRAKSK NGGRSLREKL DKIGLNLPAG RRKAAHVTLL TSLVEGEAVH LARDFAYVCE 
AEFPSKAVAD YLTRPHLGGR NEMATRKSML LAAQQVCKEF TDLLHQDRTP NGNNRPAQVL 
EPNIQNCLSH FSLITHGFGS QAICAAVSAV QNYIKEALIA IDKSYMNPGD QSPADSSKTM 
EKMEKHRK

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.