Details for: ALDH1A1

Gene ID: 216

Symbol: ALDH1A1

Ensembl ID: ENSG00000165092

Description: aldehyde dehydrogenase 1 family member A1

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 250.2166
    Cell Significance Index: -38.9200
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 137.9102
    Cell Significance Index: -34.9800
  • Cell Name: embryonic stem cell (CL0002322)
    Fold Change: 102.0761
    Cell Significance Index: -42.0500
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 96.6383
    Cell Significance Index: -39.2600
  • Cell Name: ileal goblet cell (CL1000326)
    Fold Change: 67.4493
    Cell Significance Index: -45.2600
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 41.1210
    Cell Significance Index: -39.2600
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 36.2706
    Cell Significance Index: -44.7200
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 17.1342
    Cell Significance Index: -45.9000
  • Cell Name: thyroid follicular cell (CL0002258)
    Fold Change: 14.3400
    Cell Significance Index: 152.3600
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 11.7763
    Cell Significance Index: -46.4700
  • Cell Name: centrilobular region hepatocyte (CL0019029)
    Fold Change: 4.7952
    Cell Significance Index: 80.7800
  • Cell Name: enteric smooth muscle cell (CL0002504)
    Fold Change: 4.3149
    Cell Significance Index: 22.7100
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 3.5681
    Cell Significance Index: 214.2100
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 3.2212
    Cell Significance Index: 1759.1700
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 2.9322
    Cell Significance Index: 402.6700
  • Cell Name: hippocampal astrocyte (CL0002604)
    Fold Change: 2.2491
    Cell Significance Index: 31.4500
  • Cell Name: corneal epithelial cell (CL0000575)
    Fold Change: 1.6909
    Cell Significance Index: 24.0700
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 1.6011
    Cell Significance Index: 317.7500
  • Cell Name: pancreatic endocrine cell (CL0008024)
    Fold Change: 1.5991
    Cell Significance Index: 182.5400
  • Cell Name: hepatoblast (CL0005026)
    Fold Change: 1.5916
    Cell Significance Index: 26.7700
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 1.2991
    Cell Significance Index: 37.4300
  • Cell Name: columnar/cuboidal epithelial cell (CL0000075)
    Fold Change: 1.2784
    Cell Significance Index: 4.9000
  • Cell Name: peg cell (CL4033014)
    Fold Change: 1.2176
    Cell Significance Index: 28.1300
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 1.2033
    Cell Significance Index: 2219.2500
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: 1.1368
    Cell Significance Index: 194.1100
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: 1.0749
    Cell Significance Index: 55.9900
  • Cell Name: fallopian tube secretory epithelial cell (CL4030006)
    Fold Change: 1.0451
    Cell Significance Index: 16.1700
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.9726
    Cell Significance Index: 1497.2300
  • Cell Name: tuft cell of small intestine (CL0009080)
    Fold Change: 0.9204
    Cell Significance Index: 9.2900
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.8797
    Cell Significance Index: 95.6800
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.8273
    Cell Significance Index: 1557.7300
  • Cell Name: Sertoli cell (CL0000216)
    Fold Change: 0.7892
    Cell Significance Index: 11.0700
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.7886
    Cell Significance Index: 54.5400
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.7091
    Cell Significance Index: 70.1500
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: 0.6699
    Cell Significance Index: 17.9500
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: 0.6686
    Cell Significance Index: 13.0500
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: 0.5879
    Cell Significance Index: 12.5200
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.5756
    Cell Significance Index: 93.6100
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: 0.5453
    Cell Significance Index: 15.6300
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.5120
    Cell Significance Index: 226.3800
  • Cell Name: kidney cell (CL1000497)
    Fold Change: 0.5098
    Cell Significance Index: 4.0700
  • Cell Name: periportal region hepatocyte (CL0019026)
    Fold Change: 0.5034
    Cell Significance Index: 7.4300
  • Cell Name: theca cell (CL0000503)
    Fold Change: 0.4783
    Cell Significance Index: 2.8100
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: 0.4211
    Cell Significance Index: 29.7900
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.3985
    Cell Significance Index: 359.8000
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.3932
    Cell Significance Index: 74.8200
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.3276
    Cell Significance Index: 14.8500
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: 0.3177
    Cell Significance Index: 25.1600
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: 0.2780
    Cell Significance Index: 203.8200
  • Cell Name: skeletal muscle fibroblast (CL0011027)
    Fold Change: 0.2701
    Cell Significance Index: 1.8300
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 0.2156
    Cell Significance Index: 293.2000
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 0.1590
    Cell Significance Index: 100.9600
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.0724
    Cell Significance Index: 8.9000
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 0.0716
    Cell Significance Index: 9.1800
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: 0.0418
    Cell Significance Index: 1.3400
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.0275
    Cell Significance Index: 5.5300
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.0263
    Cell Significance Index: 4.7500
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: 0.0246
    Cell Significance Index: 18.6400
  • Cell Name: respiratory goblet cell (CL0002370)
    Fold Change: 0.0010
    Cell Significance Index: 0.0100
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0016
    Cell Significance Index: -1.2200
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: -0.0101
    Cell Significance Index: -0.2600
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0143
    Cell Significance Index: -1.4700
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0278
    Cell Significance Index: -12.6300
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0278
    Cell Significance Index: -17.3900
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: -0.0304
    Cell Significance Index: -1.5400
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0504
    Cell Significance Index: -28.4000
  • Cell Name: skeletal muscle satellite stem cell (CL0008011)
    Fold Change: -0.0589
    Cell Significance Index: -0.6200
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.0666
    Cell Significance Index: -14.0200
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: -0.0696
    Cell Significance Index: -0.9500
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.0792
    Cell Significance Index: -9.0700
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: -0.1063
    Cell Significance Index: -38.1300
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.1254
    Cell Significance Index: -36.0800
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: -0.1269
    Cell Significance Index: -2.7500
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.1735
    Cell Significance Index: -20.2200
  • Cell Name: BEST4+ enteroycte (CL4030026)
    Fold Change: -0.2515
    Cell Significance Index: -3.7900
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.2834
    Cell Significance Index: -41.2000
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.3136
    Cell Significance Index: -40.5100
  • Cell Name: taste receptor cell (CL0000209)
    Fold Change: -0.3609
    Cell Significance Index: -4.2000
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: -0.3839
    Cell Significance Index: -45.2700
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.3900
    Cell Significance Index: -40.6100
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: -0.4482
    Cell Significance Index: -12.2000
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: -0.4512
    Cell Significance Index: -12.6100
  • Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
    Fold Change: -0.5086
    Cell Significance Index: -9.4000
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.5897
    Cell Significance Index: -43.9500
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.6338
    Cell Significance Index: -35.5700
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.6380
    Cell Significance Index: -29.9900
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: -0.6522
    Cell Significance Index: -19.2100
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: -0.6654
    Cell Significance Index: -42.9300
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: -0.6796
    Cell Significance Index: -17.8700
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.6811
    Cell Significance Index: -45.8000
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: -0.6874
    Cell Significance Index: -32.0500
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -0.6901
    Cell Significance Index: -52.9600
  • Cell Name: astrocyte (CL0000127)
    Fold Change: -0.7366
    Cell Significance Index: -8.4300
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.7385
    Cell Significance Index: -45.2800
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -0.7448
    Cell Significance Index: -46.9400
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.7821
    Cell Significance Index: -48.0700
  • Cell Name: intestinal epithelial cell (CL0002563)
    Fold Change: -0.8936
    Cell Significance Index: -9.2500
  • Cell Name: eukaryotic cell (CL0000255)
    Fold Change: -0.8981
    Cell Significance Index: -39.0500
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: -0.9172
    Cell Significance Index: -15.3500
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: -0.9244
    Cell Significance Index: -48.0200

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics** 1. **Aldehyde Dehydrogenase Activity**: ALDH1A1 is a member of the aldehyde dehydrogenase family, which catalyzes the oxidation of aldehydes to their corresponding carboxylic acids. This enzyme is essential for the detoxification of aldehydes, which are reactive molecules that can cause cellular damage if not properly metabolized. 2. **Retinoid Metabolism**: ALDH1A1 is involved in the metabolism of retinoids, including retinaldehyde and retinoic acid. These compounds are essential for vision, development, and cell growth, and their metabolism is tightly regulated by ALDH1A1. 3. **Cellular Localization**: ALDH1A1 is primarily expressed in cells of the anterior lens, retina, thyroid gland, and tracheobronchial tree. It is also found in other cells, including hepatoblasts and secretory cells. 4. **Signaling Pathways**: ALDH1A1 is involved in various signaling pathways, including the regulation of androgen binding, axon development, and the maintenance of lens transparency. **Pathways and Functions** 1. **3-Deoxyglucosone Dehydrogenase Activity**: ALDH1A1 catalyzes the oxidation of 3-deoxyglucosone, a toxic compound that can cause cellular damage. 2. **Aldehyde Dehydrogenase (NAD+) Activity**: ALDH1A1 oxidizes aldehydes to their corresponding carboxylic acids, using NAD+ as a cofactor. 3. **Aminobutyraldehyde Dehydrogenase Activity**: ALDH1A1 also catalyzes the oxidation of aminobutyraldehyde, a toxic compound that can cause cellular damage. 4. **Retinoid Metabolic Process**: ALDH1A1 is involved in the metabolism of retinoids, including retinaldehyde and retinoic acid. 5. **Glyceraldehyde-3-Phosphate Dehydrogenase (NAD+) (Non-Phosphorylating) Activity**: ALDH1A1 also catalyzes the oxidation of glyceraldehyde-3-phosphate, a key intermediate in glycolysis. **Clinical Significance** 1. **Aldehyde Poisoning**: ALDH1A1 deficiency has been implicated in aldehyde poisoning, a condition characterized by the accumulation of toxic aldehydes in the body. 2. **Retinoid-Related Disorders**: ALDH1A1 is involved in the metabolism of retinoids, and its dysfunction has been implicated in retinoid-related disorders, including retinal degeneration and cancer. 3. **Thyroid Cancer**: ALDH1A1 has been identified as a potential biomarker for thyroid cancer, as it is highly expressed in thyroid cancer cells. 4. **Neurological Disorders**: ALDH1A1 has also been implicated in neurological disorders, including Parkinson's disease and Alzheimer's disease, where it is involved in the metabolism of neuroactive compounds. In conclusion, the ALDH1A1 gene plays a crucial role in various cellular processes, including metabolism, detoxification, and signaling pathways. Its dysfunction has been implicated in various diseases, including aldehyde poisoning, retinoid-related disorders, thyroid cancer, and neurological disorders. Further research is needed to fully understand the role of ALDH1A1 in human health and disease.

Genular Protein ID: 2942757979

Symbol: AL1A1_HUMAN

Name: ALDH-E1

UniProtKB Accession Codes:

P00352 O00768 Q5SYR1

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 BRENDA 1 Bgee 1 BindingDB 1 BioCyc 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CDD 1 CTD 1 ChEBI 85 ChEMBL 1 ChiTaRS 1 DMDM 1 DNASU 1 DisGeNET 1 DrugBank 5 DrugCentral 1 EC 5 EMBL 22 EMDB 3 Ensembl 1 EvolutionaryTrace 1 ExpressionAtlas 1 GO 22 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 6 KEGG 1 MANE-Select 1 MIM 1 MassIVE 1 MetOSite 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 24 PDBsum 24 PIR 1 PRO 1 PROSITE 2 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 Pumba 1 REPRODUCTION-2DPAGE 2 RNAct 1 Reactome 3 RefSeq 1 Rhea 26 SABIO-RK 1 SIGNOR 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 SwissPalm 1 TreeFam 1 UniPathway 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 2591967

Title: Genomic structure of the human cytosolic aldehyde dehydrogenase gene.

PubMed ID: 2591967

DOI: 10.1016/0888-7543(89)90127-4

PubMed ID: 8214422

Title: Cloning and expression of the full-length cDNAs encoding human liver class 1 and class 2 aldehyde dehydrogenase.

PubMed ID: 8214422

DOI: 10.1111/j.1530-0277.1993.tb00849.x

PubMed ID: 19296407

Title: Molecular cloning and oxidative modification of human lens ALDH1A1: implication in impaired detoxification of lipid aldehydes.

PubMed ID: 19296407

DOI: 10.1080/15287390802706371

PubMed ID: 15164053

Title: DNA sequence and analysis of human chromosome 9.

PubMed ID: 15164053

DOI: 10.1038/nature02465

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 8493914

Title: Biological role of human cytosolic aldehyde dehydrogenase 1: hormonal response, retinal oxidation and implication in testicular feminization.

PubMed ID: 8493914

DOI: 10.1007/978-1-4615-2904-0_5

PubMed ID: 6723659

Title: Aldehyde dehydrogenase from human liver. Primary structure of the cytoplasmic isoenzyme.

PubMed ID: 6723659

DOI: 10.1111/j.1432-1033.1984.tb08150.x

PubMed ID: 4015823

Title: Molecular abnormality and cDNA cloning of human aldehyde dehydrogenases.

PubMed ID: 4015823

DOI: 10.1016/0741-8329(85)90024-2

PubMed ID: 2987944

Title: Cloning of cDNAs for human aldehyde dehydrogenases 1 and 2.

PubMed ID: 2987944

DOI: 10.1073/pnas.82.11.3771

PubMed ID: 3676276

Title: Active site of human liver aldehyde dehydrogenase.

PubMed ID: 3676276

DOI: 10.1021/bi00392a015

PubMed ID: 2776714

Title: Aldehyde dehydrogenase from human erythrocytes: structural relationship to the liver cytosolic isozyme.

PubMed ID: 2776714

DOI: 10.1159/000469006

PubMed ID: 12941160

Title: Molecular cloning and baculovirus expression of the rabbit corneal aldehyde dehydrogenase (ALDH1A1) cDNA.

PubMed ID: 12941160

DOI: 10.1089/104454903322216671

PubMed ID: 15623782

Title: Role of aldehyde dehydrogenase isozymes in the defense of rat lens and human lens epithelial cells against oxidative stress.

PubMed ID: 15623782

DOI: 10.1167/iovs.04-0120

PubMed ID: 17175089

Title: Identification of 3-deoxyglucosone dehydrogenase as aldehyde dehydrogenase 1A1 (retinaldehyde dehydrogenase 1).

PubMed ID: 17175089

DOI: 10.1016/j.biochi.2006.11.005

PubMed ID: 19608861

Title: Lysine acetylation targets protein complexes and co-regulates major cellular functions.

PubMed ID: 19608861

DOI: 10.1126/science.1175371

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 22223895

Title: Comparative large-scale characterisation of plant vs. mammal proteins reveals similar and idiosyncratic N-alpha acetylation features.

PubMed ID: 22223895

DOI: 10.1074/mcp.m111.015131

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 33495566

Title: PRMT3 interacts with ALDH1A1 and regulates gene-expression by inhibiting retinoic acid signaling.

PubMed ID: 33495566

DOI: 10.1038/s42003-020-01644-3

PubMed ID: 26373694

Title: Structural, biochemical, and computational studies reveal the mechanism of selective aldehyde dehydrogenase 1A1 inhibition by cytotoxic duocarmycin analogues.

PubMed ID: 26373694

DOI: 10.1002/anie.201505749

PubMed ID: 25450233

Title: Development of a high-throughput in vitro assay to identify selective inhibitors for human ALDH1A1.

PubMed ID: 25450233

DOI: 10.1016/j.cbi.2014.10.028

PubMed ID: 25634381

Title: Characterization of two distinct structural classes of selective aldehyde dehydrogenase 1A1 inhibitors.

PubMed ID: 25634381

DOI: 10.1021/jm501900s

Sequence Information:

  • Length: 501
  • Mass: 54862
  • Checksum: B26464DC7168348E
  • Sequence:
    • MSSSGTPDLP VLLTDLKIQY TKIFINNEWH DSVSGKKFPV FNPATEEELC QVEEGDKEDV 
DKAVKAARQA FQIGSPWRTM DASERGRLLY KLADLIERDR LLLATMESMN GGKLYSNAYL 
NDLAGCIKTL RYCAGWADKI QGRTIPIDGN FFTYTRHEPI GVCGQIIPWN FPLVMLIWKI 
GPALSCGNTV VVKPAEQTPL TALHVASLIK EAGFPPGVVN IVPGYGPTAG AAISSHMDID 
KVAFTGSTEV GKLIKEAAGK SNLKRVTLEL GGKSPCIVLA DADLDNAVEF AHHGVFYHQG 
QCCIAASRIF VEESIYDEFV RRSVERAKKY ILGNPLTPGV TQGPQIDKEQ YDKILDLIES 
GKKEGAKLEC GGGPWGNKGY FVQPTVFSNV TDEMRIAKEE IFGPVQQIMK FKSLDDVIKR 
ANNTFYGLSA GVFTKDIDKA ITISSALQAG TVWVNCYGVV SAQCPFGGFK MSGNGRELGE 
YGFHEYTEVK TVTVKISQKN S

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.