Details for: Sry

Gene ID: 21674

Symbol: Sry

Ensembl ID: ENSMUSG00000069036

Description: sex determining region of Chr Y

Associated with

Other Information

Genular Protein ID: 768834384

Symbol: SRY_MOUSE

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 1518820

Title: Inverted repeat structure of the Sry locus in mice.

PubMed ID: 1518820

DOI: 10.1073/pnas.89.17.7953

PubMed ID: 8355784

Title: Rapid evolution of the sex determining locus in Old World mice and rats.

PubMed ID: 8355784

DOI: 10.1038/364715a0

PubMed ID: 8012385

Title: Polymorphism of a CAG trinucleotide repeat within Sry correlates with B6.YDom sex reversal.

PubMed ID: 8012385

DOI: 10.1038/ng0394-245

PubMed ID: 33004521

Title: The mouse Sry locus harbors a cryptic exon that is essential for male sex determination.

PubMed ID: 33004521

DOI: 10.1126/science.abb6430

PubMed ID: 2374589

Title: A gene mapping to the sex-determining region of the mouse Y chromosome is a member of a novel family of embryonically expressed genes.

PubMed ID: 2374589

DOI: 10.1038/346245a0

PubMed ID: 8190643

Title: Definition of a consensus DNA binding site for SRY.

PubMed ID: 8190643

DOI: 10.1093/nar/22.8.1500

PubMed ID: 8159753

Title: Distinct DNA-binding properties of the high mobility group domain of murine and human SRY sex-determining factors.

PubMed ID: 8159753

DOI: 10.1073/pnas.91.8.3368

PubMed ID: 7600978

Title: Expression of Sry, the mouse sex determining gene.

PubMed ID: 7600978

DOI: 10.1242/dev.121.6.1603

PubMed ID: 7670499

Title: Expression of a linear Sry transcript in the mouse genital ridge.

PubMed ID: 7670499

DOI: 10.1038/ng0895-480

PubMed ID: 11085593

Title: Developmental profile of Sry transcripts in mouse brain.

PubMed ID: 11085593

DOI: 10.1007/s100480000093

PubMed ID: 11784049

Title: Evidence that Sry is expressed in pre-Sertoli cells and Sertoli and granulosa cells have a common precursor.

PubMed ID: 11784049

DOI: 10.1006/dbio.2001.0438

PubMed ID: 11535586

Title: The C-terminal nuclear localization signal of the sex-determining region Y (SRY) high mobility group domain mediates nuclear import through importin beta 1.

PubMed ID: 11535586

DOI: 10.1074/jbc.m101668200

PubMed ID: 15170344

Title: Sry-directed sex reversal in transgenic mice is robust with respect to enhanced DNA bending: comparison of human and murine HMG boxes.

PubMed ID: 15170344

DOI: 10.1021/bi049920a

PubMed ID: 15297880

Title: Regulation of human SRY subcellular distribution by its acetylation/deacetylation.

PubMed ID: 15297880

DOI: 10.1038/sj.emboj.7600352

PubMed ID: 15469996

Title: Sry associates with the heterochromatin protein 1 complex by interacting with a KRAB domain protein.

PubMed ID: 15469996

DOI: 10.1095/biolreprod.104.034447

PubMed ID: 16166090

Title: NHERF2/SIP-1 interacts with mouse SRY via a different mechanism than human SRY.

PubMed ID: 16166090

DOI: 10.1074/jbc.m504127200

PubMed ID: 16488877

Title: Direct regulation of adult brain function by the male-specific factor SRY.

PubMed ID: 16488877

DOI: 10.1016/j.cub.2006.01.017

PubMed ID: 16904257

Title: The poly(ADP-ribose) polymerase 1 interacts with Sry and modulates its biological functions.

PubMed ID: 16904257

DOI: 10.1016/j.mce.2006.06.008

PubMed ID: 19349578

Title: Exportin 4 mediates a novel nuclear import pathway for Sox family transcription factors.

PubMed ID: 19349578

DOI: 10.1083/jcb.200810106

PubMed ID: 16996051

Title: Sry and the hesitant beginnings of male development.

PubMed ID: 16996051

DOI: 10.1016/j.ydbio.2006.08.049

PubMed ID: 16414182

Title: KRAB: a partner for SRY action on chromatin.

PubMed ID: 16414182

DOI: 10.1016/j.mce.2005.12.011

Sequence Information:

  • Length: 392
  • Mass: 49124
  • Checksum: 00732B378D702B40
  • Sequence:
  • MEGHVKRPMN AFMVWSRGER HKLAQQNPSM QNTEISKQLG CRWKSLTEAE KRPFFQEAQR 
    LKILHREKYP NYKYQPHRRA KVSQRSGILQ PAVASTKLYN LLQWDRNPHA ITYRQDWSRA 
    AHLYSKNQQS FYWQPVDIPT GHLQQQQQQQ QQQQFHNHHQ QQQQFYDHHQ QQQQQQQQQQ 
    QFHDHHQQKQ QFHDHHQQQQ QFHDHHHHHQ EQQFHDHHQQ QQQFHDHQQQ QQQQQQQQFH 
    DHHQQKQQFH DHHHHQQQQQ FHDHQQQQQQ FHDHQQQQHQ FHDHPQQKQQ FHDHPQQQQQ 
    FHDHHHQQQQ KQQFHDHHQQ KQQFHDHHQQ KQQFHDHHQQ QQQFHDHHQQ QQQQQQQQQQ 
    QFHDQQLTYL LTADITGWKG IKHCTGPDPE PF

Genular Protein ID: 894592294

Symbol: Q53WV7_MOUSE

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 9383069

Title: DNA sequence analysis of Sry alleles (subgenus Mus) implicates misregulation as the cause of C57BL/6J-Y(POS) sex reversal and defines the SRY functional unit.

PubMed ID: 9383069

Sequence Information:

  • Length: 395
  • Mass: 49494
  • Checksum: FFBE9C35161CD80C
  • Sequence:
  • MEGHVKRPMN AFMVWSRGER HKLAQQNPSM QNTEISKQLG CRWKSLTEAE KRPFFQEAQR 
    LKILHREKYP NYKYQPHRRA KVSQRSGILQ PAVASTKLYN LLQWDRNPHA ITYRQDWSRA 
    AHLYSKNQQS FYWQPVDIPT GHLQQQQQQQ QQQQFHNHHQ QQQQFYDHHQ QQQQQQQQQQ 
    QFHDHHQQKQ QFHDHHQQQQ QFHDHHHHHQ EQQFHDHHQQ QQQFHDHQQQ QQQQQQQQFH 
    DHHQQKQQFH DHHHHQQQQQ FHDHQQQQQQ FHDHQQQQHQ FHDHPQQKQQ FHDHPQQQQQ 
    FHDHHHQQQQ KQQFHDHHQQ KQQFHDHHQQ KQQFHDHHQQ QQQFHDHHQQ QQQQQQQQQQ 
    QFHDQQLTYL LTADITGEHT PYQEHLSTAL WLAVS

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.