Details for: Tek
Associated with
Other Information
Genular Protein ID: 3963245008
Symbol: TIE2_MOUSE
Name: Angiopoietin-1 receptor
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 8415706
Title: Tie-1 and tie-2 define another class of putative receptor tyrosine kinase genes expressed in early embryonic vascular system.
PubMed ID: 8415706
PubMed ID: 8386827
Title: The endothelial-specific receptor tyrosine kinase, tek, is a member of a new subfamily of receptors.
PubMed ID: 8386827
PubMed ID: 1282811
Title: A novel tyrosine kinase, hyk, expressed in murine embryonic stem cells.
PubMed ID: 1282811
PubMed ID: 8217221
Title: Tie2, a putative protein tyrosine kinase from a new class of cell surface receptor.
PubMed ID: 8217221
PubMed ID: 8187650
Title: Expression of tie-2, a member of a novel family of receptor tyrosine kinases, in the endothelial cell lineage.
PubMed ID: 8187650
PubMed ID: 8395828
Title: Molecular cloning and characterization of mouse TIE and TEK receptor tyrosine kinase genes and their expression in hematopoietic stem cells.
PubMed ID: 8395828
PubMed ID: 1630810
Title: Tek, a novel tyrosine kinase gene located on mouse chromosome 4, is expressed in endothelial cells and their presumptive precursors.
PubMed ID: 1630810
PubMed ID: 7958865
Title: Dominant-negative and targeted null mutations in the endothelial receptor tyrosine kinase, tek, reveal a critical role in vasculogenesis of the embryo.
PubMed ID: 7958865
PubMed ID: 7596437
Title: Distinct roles of the receptor tyrosine kinases Tie-1 and Tie-2 in blood vessel formation.
PubMed ID: 7596437
DOI: 10.1038/376070a0
PubMed ID: 9632797
Title: Tyrosine 1101 of Tie2 is the major site of association of p85 and is required for activation of phosphatidylinositol 3-kinase and Akt.
PubMed ID: 9632797
PubMed ID: 10521483
Title: Identification of Tek/Tie2 binding partners. Binding to a multifunctional docking site mediates cell survival and migration.
PubMed ID: 10521483
PubMed ID: 10557082
Title: Functional interaction of vascular endothelial-protein-tyrosine phosphatase with the angiopoietin receptor Tie-2.
PubMed ID: 10557082
PubMed ID: 11375937
Title: Rescue of the early vascular defects in Tek/Tie2 null mice reveals an essential survival function.
PubMed ID: 11375937
PubMed ID: 12427764
Title: Angiopoietin-1 and angiopoietin-2 share the same binding domains in the Tie-2 receptor involving the first Ig-like loop and the epidermal growth factor-like repeats.
PubMed ID: 12427764
PubMed ID: 12665569
Title: A unique autophosphorylation site on Tie2/Tek mediates Dok-R phosphotyrosine binding domain binding and function.
PubMed ID: 12665569
PubMed ID: 15284220
Title: Biological characterization of angiopoietin-3 and angiopoietin-4.
PubMed ID: 15284220
PubMed ID: 19451274
Title: VE-PTP controls blood vessel development by balancing Tie-2 activity.
PubMed ID: 19451274
PubMed ID: 21183079
Title: A tissue-specific atlas of mouse protein phosphorylation and expression.
PubMed ID: 21183079
PubMed ID: 20973951
PubMed ID: 27270174
Title: Angiopoietin receptor TEK mutations underlie primary congenital glaucoma with variable expressivity.
PubMed ID: 27270174
DOI: 10.1172/jci85830
PubMed ID: 28179430
Title: Polydom Is an Extracellular Matrix Protein Involved in Lymphatic Vessel Remodeling.
PubMed ID: 28179430
Sequence Information:
- Length: 1122
- Mass: 125701
- Checksum: F879623D103FFE96
- Sequence:
MDSLAGLVLC GVSLLLYGVV EGAMDLILIN SLPLVSDAET SLTCIASGWH PHEPITIGRD FEALMNQHQD PLEVTQDVTR EWAKKVVWKR EKASKINGAY FCEGRVRGQA IRIRTMKMRQ QASFLPATLT MTVDRGDNVN ISFKKVLIKE EDAVIYKNGS FIHSVPRHEV PDILEVHLPH AQPQDAGVYS ARYIGGNLFT SAFTRLIVRR CEAQKWGPDC SRPCTTCKNN GVCHEDTGEC ICPPGFMGRT CEKACEPHTF GRTCKERCSG PEGCKSYVFC LPDPYGCSCA TGWRGLQCNE ACPSGYYGPD CKLRCHCTNE EICDRFQGCL CSQGWQGLQC EKEGRPRMTP QIEDLPDHIE VNSGKFNPIC KASGWPLPTS EEMTLVKPDG TVLQPNDFNY TDRFSVAIFT VNRVLPPDSG VWVCSVNTVA GMVEKPFNIS VKVLPEPLHA PNVIDTGHNF AIINISSEPY FGDGPIKSKK LFYKPVNQAW KYIEVTNEIF TLNYLEPRTD YELCVQLARP GEGGEGHPGP VRRFTTASIG LPPPRGLSLL PKSQTALNLT WQPIFTNSED EFYVEVERRS LQTTSDQQNI KVPGNLTSVL LSNLVPREQY TVRARVNTKA QGEWSEELRA WTLSDILPPQ PENIKISNIT DSTAMVSWTI VDGYSISSII IRYKVQGKNE DQHIDVKIKN ATVTQYQLKG LEPETTYHVD IFAENNIGSS NPAFSHELRT LPHSPASADL GGGKMLLIAI LGSAGMTCIT VLLAFLIMLQ LKRANVQRRM AQAFQNREEP AVQFNSGTLA LNRKAKNNPD PTIYPVLDWN DIKFQDVIGE GNFGQVLKAR IKKDGLRMDA AIKRMKEYAS KDDHRDFAGE LEVLCKLGHH PNIINLLGAC EHRGYLYLAI EYAPHGNLLD FLRKSRVLET DPAFAIANST ASTLSSQQLL HFAADVARGM DYLSQKQFIH RDLAARNILV GENYIAKIAD FGLSRGQEVY VKKTMGRLPV RWMAIESLNY SVYTTNSDVW SYGVLLWEIV SLGGTPYCGM TCAELYEKLP QGYRLEKPLN CDDEVYDLMR QCWREKPYER PSFAQILVSL NRMLEERKTY VNTTLYEKFT YAGIDCSAEE AA
Genular Protein ID: 3417431139
Symbol: Q80YS4_MOUSE
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 19468303
Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.
PubMed ID: 19468303
PubMed ID: 21183079
Title: A tissue-specific atlas of mouse protein phosphorylation and expression.
PubMed ID: 21183079
Sequence Information:
- Length: 1072
- Mass: 120048
- Checksum: E652FFB247D1ABB6
- Sequence:
MDSLAGLVLC GVSLLLYGVV EGAMDLILIN SLPLVSDAET SLTCIASGWH PHEPITIGRD FEALMNQHQD PLEVTQDVTR EWAKKVVWKR EKASKINGAY FCEGRVRGQA IRIRTMKMRQ QASFLPATLT MTVDRGDNVN ISFKKVLIKE EDAVIYKNGC EAQKWGPDCS RPCTTCKNNG VCHEDTGECI CPPGFMGRTC EKACEPHTFG RTCKERCSGP EGCKSYVFCL PDPYGCSCAT GWRGLQCNEA CPSGYYGPDC KLRCHCTNEE ICDRFQGCLC SQGWQGLQCE KEGRPRMTPQ IEDLPDHIEV NSGKFNPICK ASGWPLPTSE EMTLVKPDGT VLQPNDFNYT DRFSVAIFTV NRVLPPDSGV WVCSVNTVAG MVEKPFNISV KVLPEPLHAP NVIDTGHNFA IINISSEPYF GDGPIKSKKL FYKPVNQAWK YIEVTNEIFT LNYLEPRTDY ELCVQLARPG EGGEGHPGPV RRFTTASIGL PPPRGLSLLP KSQTALNLTW QPIFTNSEDE FYVEVERRSL QTTSDQQNIK VPGNLTSVLL SNLVPREQYT VRARVNTKAQ GEWSEELRAW TLSDILPPQP ENIKISNITD STAMVSWTIV DGYSISSIII RYKVQGKNED QHIDVKIKNA TVTQYQLKGL EPETTYHVDI FAENNIGSSN PAFSHELRTL PHSPASADLG GGKMLLIAIL GSAGMTCITV LLAFLIMLQL KRANVQRRMA QAFQNVREEP AVQFNSGTLA LNRKAKNNPD PTIYPVLDWN DIKFQDVIGE GNFGQVLKAR IKKDGLRMDA AIKRMKEYAS KDDHRDFAGE LEVLCKLGHH PNIINLLGAC EHRGYLYLAI EYAPHGNLLD FLRKSRVLET DPAFAIANST ASTLSSQQLL HFAADVARGM DYLSQKQFIH RDLAARNILV GENYIAKIAD FGLSRGQEVY VKKTMGRLPV RWMAIESLNY SVYTTNSDVW SYGVLLWEIV SLGGTPYCGM TCAELYEKLP QGYRLEKPLN CDDEVYDLMR QCWREKPYER PSFAQILVSL NRMLEERKTY VNTTLYEKFT YAGIDCSAEE AA
Genular Protein ID: 840565960
Symbol: B1AWS8_MOUSE
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 19468303
Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.
PubMed ID: 19468303
PubMed ID: 21183079
Title: A tissue-specific atlas of mouse protein phosphorylation and expression.
PubMed ID: 21183079
Sequence Information:
- Length: 1123
- Mass: 125800
- Checksum: 5574147BAAA86F69
- Sequence:
MDSLAGLVLC GVSLLLYGVV EGAMDLILIN SLPLVSDAET SLTCIASGWH PHEPITIGRD FEALMNQHQD PLEVTQDVTR EWAKKVVWKR EKASKINGAY FCEGRVRGQA IRIRTMKMRQ QASFLPATLT MTVDRGDNVN ISFKKVLIKE EDAVIYKNGS FIHSVPRHEV PDILEVHLPH AQPQDAGVYS ARYIGGNLFT SAFTRLIVRR CEAQKWGPDC SRPCTTCKNN GVCHEDTGEC ICPPGFMGRT CEKACEPHTF GRTCKERCSG PEGCKSYVFC LPDPYGCSCA TGWRGLQCNE ACPSGYYGPD CKLRCHCTNE EICDRFQGCL CSQGWQGLQC EKEGRPRMTP QIEDLPDHIE VNSGKFNPIC KASGWPLPTS EEMTLVKPDG TVLQPNDFNY TDRFSVAIFT VNRVLPPDSG VWVCSVNTVA GMVEKPFNIS VKVLPEPLHA PNVIDTGHNF AIINISSEPY FGDGPIKSKK LFYKPVNQAW KYIEVTNEIF TLNYLEPRTD YELCVQLARP GEGGEGHPGP VRRFTTASIG LPPPRGLSLL PKSQTALNLT WQPIFTNSED EFYVEVERRS LQTTSDQQNI KVPGNLTSVL LSNLVPREQY TVRARVNTKA QGEWSEELRA WTLSDILPPQ PENIKISNIT DSTAMVSWTI VDGYSISSII IRYKVQGKNE DQHIDVKIKN ATVTQYQLKG LEPETTYHVD IFAENNIGSS NPAFSHELRT LPHSPASADL GGGKMLLIAI LGSAGMTCIT VLLAFLIMLQ LKRANVQRRM AQAFQNVREE PAVQFNSGTL ALNRKAKNNP DPTIYPVLDW NDIKFQDVIG EGNFGQVLKA RIKKDGLRMD AAIKRMKEYA SKDDHRDFAG ELEVLCKLGH HPNIINLLGA CEHRGYLYLA IEYAPHGNLL DFLRKSRVLE TDPAFAIANS TASTLSSQQL LHFAADVARG MDYLSQKQFI HRDLAARNIL VGENYIAKIA DFGLSRGQEV YVKKTMGRLP VRWMAIESLN YSVYTTNSDV WSYGVLLWEI VSLGGTPYCG MTCAELYEKL PQGYRLEKPL NCDDEVYDLM RQCWREKPYE RPSFAQILVS LNRMLEERKT YVNTTLYEKF TYAGIDCSAE EAA
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.