Genular: Defining Cellular Identity and Function

Details for: Tesk1

Gene ID: 21754

Symbol: Tesk1

Ensembl ID: ENSMUSG00000028458

Description: testis specific protein kinase 1

Associated with

Cell-cell communication
(R-MMU-1500931)
Cell-extracellular matrix interactions
(R-MMU-446353)
Cell junction organization
(R-MMU-446728)
Regulation of cytoskeletal remodeling and cell spreading by ipp complex components
(R-MMU-446388)
Actin cytoskeleton organization
(GO:0030036)
Atp binding
(GO:0005524)
Cell projection
(GO:0042995)
Centrosome
(GO:0005813)
Cytoplasm
(GO:0005737)
Cytoplasmic vesicle
(GO:0031410)
Cytoskeleton
(GO:0005856)
Establishment of vesicle localization
(GO:0051650)
Kinase activity
(GO:0016301)
Metal ion binding
(GO:0046872)
Negative regulation of cilium assembly
(GO:1902018)
Negative regulation of phosphorylation
(GO:0042326)
Negative regulation of protein autophosphorylation
(GO:0031953)
Nucleotide binding
(GO:0000166)
Nucleus
(GO:0005634)
Perinuclear region of cytoplasm
(GO:0048471)
Phosphorylation
(GO:0016310)
Podocyte cell migration
(GO:0090521)
Positive regulation of protein localization to nucleus
(GO:1900182)
Positive regulation of protein phosphorylation
(GO:0001934)
Positive regulation of stress fiber assembly
(GO:0051496)
Positive regulation of substrate adhesion-dependent cell spreading
(GO:1900026)
Protein kinase activity
(GO:0004672)
Protein kinase binding
(GO:0019901)
Protein phosphorylation
(GO:0006468)
Protein serine/threonine/tyrosine kinase activity
(GO:0004712)
Protein serine/threonine kinase activity
(GO:0004674)
Protein tyrosine kinase activity
(GO:0004713)
Regulation of actin cytoskeleton organization
(GO:0032956)
Regulation of protein localization
(GO:0032880)
Transferase activity
(GO:0016740)

Other Information

Proteins

Dual specificity testis-specific protein kinase 1

Genular Protein ID: 2942114363

Symbol: TESK1_MOUSE

Name: Dual specificity testis-specific protein kinase 1

UniProtKB Accession Codes:

O70146 O70147 Q499W7

Database IDs:

Citations:

PubMed ID: 9469938

Title: Structural organization and chromosomal localization of the mouse tesk1 (testis-specific protein kinase 1) gene.

PubMed ID: 9469938

DOI: 10.1016/s0378-1119(97)00591-x

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 19468303

Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.

PubMed ID: 19468303

DOI: 10.1371/journal.pbio.1000112

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 17974561

Title: Tesk1 interacts with Spry2 to abrogate its inhibition of ERK phosphorylation downstream of receptor tyrosine kinase signaling.

PubMed ID: 17974561

DOI: 10.1074/jbc.m705457200

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 24129315

Title: Immunoaffinity enrichment and mass spectrometry analysis of protein methylation.

PubMed ID: 24129315

DOI: 10.1074/mcp.o113.027870

PubMed ID: 30115939

Title: Regulation of cofilin phosphorylation in glomerular podocytes by testis specific kinase 1 (TESK1).

PubMed ID: 30115939

DOI: 10.1038/s41598-018-30115-3

Sequence Information:

Length: 627
Mass: 68052
Checksum: 091ADA8CF52A2B50
Sequence:

MAGERPPLRG PGPGEAPGEG PGGAGGGPGR GRPSSYRALR SAVSSLARVD DFDCAEKIGA 
GFFSEVYKVR HRQSGQVMVL KMNKLPSNRS NTLREVQLMN RLRHPNILRF MGVCVHQGQL 
HALTEYMNGG TLEQLLSSPE PLSWPVRLHL ALDIAQGLRY LHAKGVFHRD LTSKNCLVRR 
EDRGFTAVVG DFGLAEKIPV YREGTRKEPL AVVGSPYWMA PEVLRGELYD EKADVFAFGI 
VLCELIARVP ADPDYLPRTE DFGLDVPAFR TLVGNDCPLP FLLLAIHCCS MEPSTRAPFT 
EITQHLEQIL EQQPEATPLA KPPLTKAPLT YNQGSVPRGG PSATLPRPDP RLSRSRSDLF 
LPPSPESPPS WGDNLTRVNP FSLREDLRGG KIKLLDTPCK PATPLPLVPP SPLTSTQLPL 
VTTPDILVQP ETPVRRCRSL PSSPELPRRM ETALPGPGPS PMGPTEERMD CEGSSPEPEP 
PGLAPQLPLA VATDNFISTC SSASQPWSPR SGPPLNNNPP AVVVNSPQGW AREPWNRAQH 
SLPRAAALER TEPSPPPSAP REPEEGLPCP GCCLGPFSFG FLSMCPRPTP AVARYRNLNC 
EAGSLLCHRG HHAKPPTPSL QLPGARS

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Tesk1

Associated with

Other Information

Structural organization and chromosomal localization of the mouse tesk1 (testis-specific protein kinase 1) gene. PubMed ID: 9469938

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072

Lineage-specific biology revealed by a finished genome assembly of the mouse. PubMed ID: 19468303

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Tesk1 interacts with Spry2 to abrogate its inhibition of ERK phosphorylation downstream of receptor tyrosine kinase signaling. PubMed ID: 17974561

A tissue-specific atlas of mouse protein phosphorylation and expression. PubMed ID: 21183079

Immunoaffinity enrichment and mass spectrometry analysis of protein methylation. PubMed ID: 24129315

Regulation of cofilin phosphorylation in glomerular podocytes by testis specific kinase 1 (TESK1). PubMed ID: 30115939