Genular: Defining Cellular Identity and Function

Details for: Tfam

Gene ID: 21780

Symbol: Tfam

Ensembl ID: ENSMUSG00000003923

Description: transcription factor A, mitochondrial

Associated with

Gene expression (transcription)
(R-MMU-74160)
Metabolism of proteins
(R-MMU-392499)
Mitochondrial protein degradation
(R-MMU-9837999)
Mitochondrial transcription initiation
(R-MMU-163282)
Transcription from mitochondrial promoters
(R-MMU-75944)
Chromatin binding
(GO:0003682)
Dna binding
(GO:0003677)
Heat shock protein binding
(GO:0031072)
Mitochondrial matrix
(GO:0005759)
Mitochondrial nucleoid
(GO:0042645)
Mitochondrial promoter sequence-specific dna binding
(GO:0001018)
Mitochondrial respiratory chain complex assembly
(GO:0033108)
Mitochondrial transcription
(GO:0006390)
Mitochondrial transcription factor activity
(GO:0034246)
Mitochondrion
(GO:0005739)
Nucleus
(GO:0005634)
Positive regulation of dna-templated transcription
(GO:0045893)
Protein-containing complex
(GO:0032991)
Sequence-specific dna binding
(GO:0043565)
Transcription cis-regulatory region binding
(GO:0000976)
Transcription coactivator binding
(GO:0001223)
Transcription initiation at mitochondrial promoter
(GO:0006391)

Other Information

Proteins

Testis-specific high mobility group protein

Genular Protein ID: 2678042277

Symbol: TFAM_MOUSE

Name: Testis-specific high mobility group protein

UniProtKB Accession Codes:

P40630 P97894 P97906 Q543I8 Q9DBM9

Database IDs:

Citations:

PubMed ID: 8673128

Title: A single mouse gene encodes the mitochondrial transcription factor A and a testis-specific nuclear HMG-box protein.

PubMed ID: 8673128

DOI: 10.1038/ng0796-296

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 8321234

Title: A testis-specific gene encoding a nuclear high-mobility-group box protein located in elongating spermatids.

PubMed ID: 8321234

DOI: 10.1128/mcb.13.7.4323-4330.1993

PubMed ID: 9500544

Title: Mitochondrial transcription factor A is necessary for mtDNA maintenance and embryogenesis in mice.

PubMed ID: 9500544

DOI: 10.1038/ng0398-231

PubMed ID: 17581862

Title: The mitochondrial transcription factor TFAM coordinates the assembly of multiple DNA molecules into nucleoid-like structures.

PubMed ID: 17581862

DOI: 10.1091/mbc.e07-05-0404

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 23806337

Title: SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways.

PubMed ID: 23806337

DOI: 10.1016/j.molcel.2013.06.001

Sequence Information:

Length: 243
Mass: 27988
Checksum: 3477F6EEAD9A3EBF
Sequence:

MALFRGMWSV LKALGRTGVE MCAGCGGRIP SSISLVCIPK CFSSMGSYPK KPMSSYLRFS 
TEQLPKFKAK HPDAKLSELV RKIAALWREL PEAEKKVYEA DFKAEWKAYK EAVSKYKEQL 
TPSQLMGMEK EARQRRLKKK ALVKRRELIL LGKPKRPRSA YNIYVSESFQ EAKDDSAQGK 
LKLVNEAWKN LSPEEKQAYI QLAKDDRIRY DNEMKSWEEQ MAEVGRSDLI RRSVKRSGDI 
SEH

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Tfam

Associated with

Other Information

A single mouse gene encodes the mitochondrial transcription factor A and a testis-specific nuclear HMG-box protein. PubMed ID: 8673128

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072

A testis-specific gene encoding a nuclear high-mobility-group box protein located in elongating spermatids. PubMed ID: 8321234

Mitochondrial transcription factor A is necessary for mtDNA maintenance and embryogenesis in mice. PubMed ID: 9500544

The mitochondrial transcription factor TFAM coordinates the assembly of multiple DNA molecules into nucleoid-like structures. PubMed ID: 17581862

A tissue-specific atlas of mouse protein phosphorylation and expression. PubMed ID: 21183079

SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways. PubMed ID: 23806337