Details for: ALDH3A1

Gene ID: 218

Symbol: ALDH3A1

Ensembl ID: ENSG00000108602

Description: aldehyde dehydrogenase 3 family member A1

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 20.8166
    Cell Significance Index: -5.2800
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 6.2600
    Cell Significance Index: 85.4100
  • Cell Name: corneal epithelial cell (CL0000575)
    Fold Change: 5.4562
    Cell Significance Index: 77.6700
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 4.1372
    Cell Significance Index: -3.9500
  • Cell Name: epithelial cell of lacrimal sac (CL1000436)
    Fold Change: 2.9182
    Cell Significance Index: 21.0000
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 2.6396
    Cell Significance Index: 73.7700
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: 1.5583
    Cell Significance Index: 181.6000
  • Cell Name: stem cell of epidermis (CL1000428)
    Fold Change: 1.4812
    Cell Significance Index: 4.4100
  • Cell Name: mucous neck cell (CL0000651)
    Fold Change: 1.4758
    Cell Significance Index: 7.0300
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 1.2413
    Cell Significance Index: 236.2400
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 1.1294
    Cell Significance Index: 499.3400
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 0.9118
    Cell Significance Index: 54.7400
  • Cell Name: basal cell of epithelium of trachea (CL1000348)
    Fold Change: 0.8567
    Cell Significance Index: 7.3700
  • Cell Name: retinal blood vessel endothelial cell (CL0002585)
    Fold Change: 0.8499
    Cell Significance Index: 10.9800
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: 0.7788
    Cell Significance Index: 55.0800
  • Cell Name: respiratory goblet cell (CL0002370)
    Fold Change: 0.7474
    Cell Significance Index: 7.7100
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 0.6181
    Cell Significance Index: 13.3900
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.6120
    Cell Significance Index: 60.5400
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.5983
    Cell Significance Index: 65.0800
  • Cell Name: basal cell of epidermis (CL0002187)
    Fold Change: 0.5188
    Cell Significance Index: 7.8800
  • Cell Name: oral mucosa squamous cell (CL1001576)
    Fold Change: 0.4469
    Cell Significance Index: 3.8400
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.4453
    Cell Significance Index: 402.0900
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 0.3919
    Cell Significance Index: 20.3600
  • Cell Name: precursor cell (CL0011115)
    Fold Change: 0.3719
    Cell Significance Index: 2.8200
  • Cell Name: epidermal cell (CL0000362)
    Fold Change: 0.3593
    Cell Significance Index: 0.8100
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.3468
    Cell Significance Index: 56.4100
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.3150
    Cell Significance Index: 21.7900
  • Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
    Fold Change: 0.2744
    Cell Significance Index: 3.9300
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.2592
    Cell Significance Index: 31.8700
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.1578
    Cell Significance Index: 28.4500
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: 0.0861
    Cell Significance Index: 2.3400
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.0833
    Cell Significance Index: 2.4000
  • Cell Name: tracheal goblet cell (CL1000329)
    Fold Change: 0.0774
    Cell Significance Index: 0.6400
  • Cell Name: BEST4+ enteroycte (CL4030026)
    Fold Change: 0.0544
    Cell Significance Index: 0.8200
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: 0.0324
    Cell Significance Index: 0.6900
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.0208
    Cell Significance Index: 11.3600
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: 0.0156
    Cell Significance Index: 0.3900
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.0132
    Cell Significance Index: 0.6000
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: 0.0060
    Cell Significance Index: 4.5100
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: 0.0053
    Cell Significance Index: 0.1700
  • Cell Name: ciliated columnar cell of tracheobronchial tree (CL0002145)
    Fold Change: 0.0033
    Cell Significance Index: 0.0300
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.0028
    Cell Significance Index: 0.1000
  • Cell Name: eukaryotic cell (CL0000255)
    Fold Change: 0.0027
    Cell Significance Index: 0.1200
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.0020
    Cell Significance Index: -0.1200
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: -0.0029
    Cell Significance Index: -5.4100
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0029
    Cell Significance Index: -5.3800
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.0058
    Cell Significance Index: -8.9000
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0067
    Cell Significance Index: -9.1200
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0070
    Cell Significance Index: -5.1200
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0071
    Cell Significance Index: -4.5400
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: -0.0090
    Cell Significance Index: -0.4500
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0091
    Cell Significance Index: -6.7700
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0103
    Cell Significance Index: -5.8400
  • Cell Name: neuron associated cell (CL0000095)
    Fold Change: -0.0104
    Cell Significance Index: -0.4300
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: -0.0129
    Cell Significance Index: -4.6100
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0136
    Cell Significance Index: -6.1600
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: -0.0140
    Cell Significance Index: -2.7700
  • Cell Name: odontoblast (CL0000060)
    Fold Change: -0.0195
    Cell Significance Index: -2.5000
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0238
    Cell Significance Index: -6.8500
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0257
    Cell Significance Index: -2.6300
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: -0.0276
    Cell Significance Index: -5.5400
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0327
    Cell Significance Index: -4.7500
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: -0.0353
    Cell Significance Index: -1.8400
  • Cell Name: endothelial cell of venule (CL1000414)
    Fold Change: -0.0396
    Cell Significance Index: -0.4500
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.0419
    Cell Significance Index: -7.1500
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: -0.0454
    Cell Significance Index: -6.2400
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: -0.0538
    Cell Significance Index: -6.3500
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.0557
    Cell Significance Index: -6.3800
  • Cell Name: helper T cell (CL0000912)
    Fold Change: -0.0598
    Cell Significance Index: -0.8500
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: -0.0726
    Cell Significance Index: -1.9500
  • Cell Name: melanocyte of skin (CL1000458)
    Fold Change: -0.0756
    Cell Significance Index: -1.0600
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.0772
    Cell Significance Index: -5.1900
  • Cell Name: epithelial cell (CL0000066)
    Fold Change: -0.0844
    Cell Significance Index: -0.8900
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.0901
    Cell Significance Index: -5.5400
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: -0.0907
    Cell Significance Index: -5.8500
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.0972
    Cell Significance Index: -12.5600
  • Cell Name: neuroendocrine cell (CL0000165)
    Fold Change: -0.1050
    Cell Significance Index: -1.3300
  • Cell Name: ciliated cell (CL0000064)
    Fold Change: -0.1090
    Cell Significance Index: -1.1800
  • Cell Name: keratinocyte (CL0000312)
    Fold Change: -0.1115
    Cell Significance Index: -2.7900
  • Cell Name: stratified epithelial cell (CL0000079)
    Fold Change: -0.1133
    Cell Significance Index: -4.1600
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.1133
    Cell Significance Index: -6.3600
  • Cell Name: intestinal epithelial cell (CL0002563)
    Fold Change: -0.1150
    Cell Significance Index: -1.1900
  • Cell Name: lung ciliated cell (CL1000271)
    Fold Change: -0.1278
    Cell Significance Index: -1.2500
  • Cell Name: squamous epithelial cell (CL0000076)
    Fold Change: -0.1291
    Cell Significance Index: -1.5700
  • Cell Name: basal cell (CL0000646)
    Fold Change: -0.1294
    Cell Significance Index: -1.5400
  • Cell Name: foveolar cell of stomach (CL0002179)
    Fold Change: -0.1304
    Cell Significance Index: -0.8500
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.1335
    Cell Significance Index: -7.0100
  • Cell Name: umbrella cell of urothelium (CL4030056)
    Fold Change: -0.1347
    Cell Significance Index: -1.2400
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: -0.1350
    Cell Significance Index: -4.6900
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.1397
    Cell Significance Index: -6.1800
  • Cell Name: respiratory basal cell (CL0002633)
    Fold Change: -0.1500
    Cell Significance Index: -1.4800
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.1516
    Cell Significance Index: -7.1300
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: -0.1572
    Cell Significance Index: -4.6300
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -0.1621
    Cell Significance Index: -5.6800
  • Cell Name: leptomeningeal cell (CL0000708)
    Fold Change: -0.1651
    Cell Significance Index: -3.5300
  • Cell Name: corneal endothelial cell (CL0000132)
    Fold Change: -0.1689
    Cell Significance Index: -2.5700
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.1705
    Cell Significance Index: -12.7100
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: -0.1707
    Cell Significance Index: -7.9600
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.1790
    Cell Significance Index: -5.7000
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: -0.1802
    Cell Significance Index: -4.8200

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** ALDH3A1 is a NADP+-preferring aldehyde dehydrogenase, meaning it catalyzes the oxidation of aldehydes to their corresponding carboxylic acids, thereby detoxifying these reactive molecules. The enzyme is composed of two subunits, which form a dimeric structure, facilitating its efficient catalytic activity. ALDH3A1 is also capable of binding to other proteins, suggesting its potential role in protein-protein interactions and signaling pathways. **Pathways and Functions:** ALDH3A1 is involved in several metabolic pathways, including: 1. **Biological oxidations**: ALDH3A1 participates in the oxidation of aldehydes, which are toxic compounds that can cause oxidative stress and cellular damage. 2. **Cellular aldehyde metabolic process**: The enzyme is responsible for the metabolism of aldehydes, which are produced during various cellular processes, such as lipid peroxidation and DNA damage. 3. **Lipid metabolic process**: ALDH3A1 plays a role in the regulation of lipid metabolism, including the oxidation of fatty acids and the detoxification of lipid-derived aldehydes. 4. **Xenobiotic metabolic process**: The enzyme is involved in the metabolism of xenobiotics, which are foreign substances that can be toxic to cells. **Clinical Significance:** ALDH3A1 has been implicated in various disease states, including: 1. **Cancer**: Altered expression of ALDH3A1 has been observed in various types of cancer, suggesting its potential role in tumorigenesis and cancer progression. 2. **Neurological disorders**: ALDH3A1 has been implicated in the pathogenesis of neurological disorders, such as Alzheimer's disease and Parkinson's disease, where oxidative stress and lipid metabolism dysregulation play a crucial role. 3. **Immunological responses**: ALDH3A1 may play a role in modulating immune responses, particularly in the context of epithelial barrier function and the regulation of inflammatory responses. In conclusion, ALDH3A1 is a crucial enzyme involved in various metabolic processes, including the detoxification of aldehydes and the regulation of lipid metabolism. Its expression in epithelial cells suggests its importance in maintaining the integrity of epithelial barriers. Further research is needed to fully elucidate the role of ALDH3A1 in disease states and to explore its potential as a therapeutic target. **Key Proteins:** ALDH3A1 is associated with the following proteins: 1. **AL3A1_HUMAN**: The human version of ALDH3A1, which is a dimeric NADP-preferring aldehyde dehydrogenase. 2. **I3L3I9_HUMAN**: A hypothetical protein associated with ALDH3A1. 3. **Q6PKA6_HUMAN**: A hypothetical protein associated with ALDH3A1. **Significantly Expressed Cells:** ALDH3A1 is expressed in various types of epithelial cells, including: 1. **Basal cell of epithelium of trachea** 2. **Foveolar cell of stomach** 3. **Nasal mucosa goblet cell** 4. **Conjunctival epithelial cell** 5. **Keratinocyte** 6. **Epithelial cell of esophagus** 7. **Stratified epithelial cell** 8. **Ciliated cell** 9. **Ciliated columnar cell of tracheobronchial tree** 10. **Mucous neck cell**

Genular Protein ID: 4033907070

Symbol: AL3A1_HUMAN

Name: Aldehyde dehydrogenase, dimeric NADP-preferring

UniProtKB Accession Codes:

P30838 A8K828 Q9BT37

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 BRENDA 1 Bgee 1 BindingDB 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CDD 1 CTD 1 ChEBI 13 ChEMBL 1 ChiTaRS 1 DMDM 1 DNASU 1 DisGeNET 1 DrugBank 1 EC 1 EMBL 11 Ensembl 3 EvolutionaryTrace 1 ExpressionAtlas 1 GO 13 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyGen 1 HGNC 1 HPA 1 InParanoid 1 IntAct 1 InterPro 7 KEGG 1 MANE-Select 1 MIM 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 6 PDBsum 6 PIR 1 PIRSF 1 PRIDE 1 PRO 1 PROSITE 2 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 Pumba 1 RNAct 1 Reactome 1 RefSeq 3 Rhea 2 SABIO-RK 1 SIGNOR 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 SwissPalm 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 1737758

Title: Human stomach aldehyde dehydrogenase cDNA and genomic cloning, primary structure, and expression in Escherichia coli.

PubMed ID: 1737758

DOI: 10.1016/s0021-9258(19)50690-1

PubMed ID: 8493892

Title: Human stomach aldehyde dehydrogenase, ALDH3.

PubMed ID: 8493892

DOI: 10.1007/978-1-4615-2904-0_16

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 16625196

Title: DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage.

PubMed ID: 16625196

DOI: 10.1038/nature04689

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 2037078

Title: Structural features of stomach aldehyde dehydrogenase distinguish dimeric aldehyde dehydrogenase as a 'variable' enzyme. 'Variable' and 'constant' enzymes within the alcohol and aldehyde dehydrogenase families.

PubMed ID: 2037078

DOI: 10.1016/0014-5793(91)80559-l

PubMed ID: 1905102

Title: Biochemical, immunological, and molecular characterization of a 'high Km' aldehyde dehydrogenase.

PubMed ID: 1905102

DOI: 10.1007/978-1-4684-5901-2_6

PubMed ID: 19608861

Title: Lysine acetylation targets protein complexes and co-regulates major cellular functions.

PubMed ID: 19608861

DOI: 10.1126/science.1175371

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 22814378

Title: N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.

PubMed ID: 22814378

DOI: 10.1073/pnas.1210303109

PubMed ID: 22021038

Title: Discovery of a novel class of covalent inhibitor for aldehyde dehydrogenases.

PubMed ID: 22021038

DOI: 10.1074/jbc.m111.293597

PubMed ID: 9250352

Title: Mutations associated with Sjogren-Larsson syndrome.

PubMed ID: 9250352

DOI: 10.1046/j.1469-1809.1997.6130235.x

Sequence Information:

  • Length: 453
  • Mass: 50395
  • Checksum: D35C488A022FAACA
  • Sequence:
    • MSKISEAVKR ARAAFSSGRT RPLQFRIQQL EALQRLIQEQ EQELVGALAA DLHKNEWNAY 
YEEVVYVLEE IEYMIQKLPE WAADEPVEKT PQTQQDELYI HSEPLGVVLV IGTWNYPFNL 
TIQPMVGAIA AGNSVVLKPS ELSENMASLL ATIIPQYLDK DLYPVINGGV PETTELLKER 
FDHILYTGST GVGKIIMTAA AKHLTPVTLE LGGKSPCYVD KNCDLDVACR RIAWGKFMNS 
GQTCVAPDYI LCDPSIQNQI VEKLKKSLKE FYGEDAKKSR DYGRIISARH FQRVMGLIEG 
QKVAYGGTGD AATRYIAPTI LTDVDPQSPV MQEEIFGPVL PIVCVRSLEE AIQFINQREK 
PLALYMFSSN DKVIKKMIAE TSSGGVAAND VIVHITLHSL PFGGVGNSGM GSYHGKKSFE 
TFSHRRSCLV RPLMNDEGLK VRYPPSPAKM TQH

Genular Protein ID: 3117574655

Symbol: Q6PKA6_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q6PKA6

Database IDs:

ARBA 9 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 1 CTD 1 ChEBI 12 ChiTaRS 1 DNASU 1 DisGeNET 1 EC 1 EMBL 2 GO 3 InterPro 7 KEGG 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PIRSF 1 PIRSR 1 PROSITE 2 PROSITE-ProRule 1 PeptideAtlas 1 Pfam 2 PharmGKB 1 RefSeq 2 Rhea 2 RuleBase 1 SAM 2 SUPFAM 1

Citations:

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

Sequence Information:

  • Length: 512
  • Mass: 57510
  • Checksum: 9316E56FCC008829
  • Sequence:
    • EVQRTPHPTF EYFFFLSRKL PGQELQGLNG REAGSLNTSP LGSCRSRSPS YRERLCQRRH 
EQDQRGREAR PRRLQLGRTR PLQFRIQQLE ALQRLIQEQE QELVGALAAD LHKNEWNAYY 
EEVVYVLEEI EYMIQKLPEW AADEPVEKTP QTQQDELYIH SEPLGVVLVI GTWNYPFNLT 
IQPMVGAIAA GNAVVLKPSE LSENMASLLA TIIPQYLDKD LYPVINGGVP ETTELLKERF 
DHILYTGSTG VGKIIMTAAA KHLTPVTLEL GGKSPCYVDK NCDLDVACRR IAWGKFMNSG 
QTCVAPDYIL CDPSIQNQIV EKLKKSLKEF YGEDAKKSRD YGRIISARHF QRVMGLIEGQ 
KVAYGGTGDA ATRYIAPTIL TDVDPQSPVM QEEIFGPVLP IVCVRSLEEA IQFINQREKP 
LALYMFSSND KVIKKMIAET SSGGVAANDV IVHITLHSLP FGGVGNSGMG SYHGKKSFET 
FSHRRSCLVR PLMNDEGLKV RYPPSPAKMT QH

Genular Protein ID: 3135564349

Symbol: I3L3I9_HUMAN

Name: N/A

UniProtKB Accession Codes:

I3L3I9

Database IDs:

ARBA 9 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CTD 1 ChEBI 12 ChiTaRS 1 DNASU 1 DisGeNET 1 EC 1 EMBL 1 Ensembl 2 ExpressionAtlas 1 GO 4 GeneTree 1 HGNC 1 HOGENOM 1 InterPro 7 MassIVE 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 2 PROSITE-ProRule 1 PeptideAtlas 2 Pfam 2 Proteomes 2 ProteomicsDB 2 RefSeq 2 Rhea 2 RuleBase 1 SMR 1 SUPFAM 1 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

PubMed ID: 16625196

Title: DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage.

PubMed ID: 16625196

DOI: 10.1038/nature04689

PubMed ID: 19608861

Title: Lysine acetylation targets protein complexes and co-regulates major cellular functions.

PubMed ID: 19608861

DOI: 10.1126/science.1175371

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

Sequence Information:

  • Length: 380
  • Mass: 41857
  • Checksum: CA6C7A516403836A
  • Sequence:
    • MIQKLPEWAA DEPVEKTPQT QQDELYIHSE PLGVVLVIGT WNYPFNLTIQ PMVGAIAAGN 
SVVLKPSELS ENMASLLATI IPQYLDKDLY PVINGGVPET TELLKERFDH ILYTGSTGVG 
KIIMTAAAKH LTPVTLELGG KSPCYVDKNC DLDVACRRIA WGKFMNSGQT CVAPDYILCD 
PSIQNQIVEK LKKSLKEFYG EDAKKSRDYG RIISARHFQR VMGLIEGQKV AYGGTGDAAT 
RYIAPTILTD VDPQSPVMQE EIFGPVLPIV CVRSLEEAIQ FINQREKPLA LYMFSSNDKV 
IKKMIAETSS GGVAANDVIV HITLHSLPFG GVGNSGMGSY HGKKSFETFS HRRSCLVRPL 
MNDEGLKVRY PPSPAKMTQH

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.