Genular: Defining Cellular Identity and Function

Details for: Tgfa

Gene ID: 21802

Symbol: Tgfa

Ensembl ID: ENSMUSG00000029999

Description: transforming growth factor alpha

Associated with

Asparagine n-linked glycosylation
(R-MMU-446203)
Cargo concentration in the er
(R-MMU-5694530)
Cargo recognition for clathrin-mediated endocytosis
(R-MMU-8856825)
Clathrin-mediated endocytosis
(R-MMU-8856828)
Copii-mediated vesicle transport
(R-MMU-204005)
Egfr downregulation
(R-MMU-182971)
Egfr interacts with phospholipase c-gamma
(R-MMU-212718)
Er to golgi anterograde transport
(R-MMU-199977)
Esr-mediated signaling
(R-MMU-8939211)
Extra-nuclear estrogen signaling
(R-MMU-9009391)
Gab1 signalosome
(R-MMU-180292)
Grb2 events in egfr signaling
(R-MMU-179812)
Intracellular signaling by second messengers
(R-MMU-9006925)
Mapk1/mapk3 signaling
(R-MMU-5684996)
Mapk family signaling cascades
(R-MMU-5683057)
Membrane trafficking
(R-MMU-199991)
Metabolism of proteins
(R-MMU-392499)
Negative regulation of the pi3k/akt network
(R-MMU-199418)
Pi5p, pp2a and ier3 regulate pi3k/akt signaling
(R-MMU-6811558)
Pip3 activates akt signaling
(R-MMU-1257604)
Post-translational protein modification
(R-MMU-597592)
Raf/map kinase cascade
(R-MMU-5673001)
Shc1 events in egfr signaling
(R-MMU-180336)
Signaling by egfr
(R-MMU-177929)
Signaling by nuclear receptors
(R-MMU-9006931)
Signaling by receptor tyrosine kinases
(R-MMU-9006934)
Signal transduction
(R-MMU-162582)
Transport to the golgi and subsequent modification
(R-MMU-948021)
Vesicle-mediated transport
(R-MMU-5653656)
Angiogenesis
(GO:0001525)
Basolateral plasma membrane
(GO:0016323)
Cell surface
(GO:0009986)
Cytoplasmic vesicle
(GO:0031410)
Epidermal growth factor receptor binding
(GO:0005154)
Epidermal growth factor receptor signaling pathway
(GO:0007173)
Erbb2-egfr signaling pathway
(GO:0038134)
Extracellular region
(GO:0005576)
Extracellular space
(GO:0005615)
Growth factor activity
(GO:0008083)
Hepatocyte proliferation
(GO:0072574)
Mammary gland alveolus development
(GO:0060749)
Membrane
(GO:0016020)
Negative regulation of apoptotic process
(GO:0043066)
Perinuclear region of cytoplasm
(GO:0048471)
Plasma membrane
(GO:0005886)
Positive regulation of cell division
(GO:0051781)
Positive regulation of cell population proliferation
(GO:0008284)
Positive regulation of epithelial cell proliferation
(GO:0050679)
Positive regulation of mapk cascade
(GO:0043410)
Positive regulation of mitotic nuclear division
(GO:0045840)
Positive regulation of peptidyl-tyrosine phosphorylation
(GO:0050731)
Protein binding
(GO:0005515)
Receptor ligand activity
(GO:0048018)
Transmembrane receptor protein tyrosine kinase activator activity
(GO:0030297)

Other Information

Proteins

Protransforming growth factor alpha

Genular Protein ID: 65035

Symbol: TGFA_MOUSE

Name: Protransforming growth factor alpha

UniProtKB Accession Codes:

P48030

Database IDs:

Citations:

PubMed ID: 1420315

Title: Nucleotide sequence and tissue distribution of mouse transforming growth factor-alpha.

PubMed ID: 1420315

DOI: 10.1016/0167-4781(92)90170-5

PubMed ID: 8877107

Title: Characterization of the mouse transforming growth factor alpha gene: its expression during eyelid development and in waved 1 tissues.

PubMed ID: 8877107

PubMed ID: 15652357

Title: Identification of MAGI-3 as a transforming growth factor-alpha tail binding protein.

PubMed ID: 15652357

DOI: 10.1016/j.yexcr.2004.10.007

Sequence Information:

Length: 159
Mass: 17018
Checksum: BE0AE8D89CE7DDFD
Sequence:

MVPATGQLAL LALGILLAVC QALENSTSPL SDSPVAAAVV SHFNKCPDSH TQYCFHGTCR 
FLVQEEKPAC VCHSGYVGVR CEHADLLAVV AASQKKQAIT ALVVVSIVAL AVLIITCVLI 
HCCQLRKHCE WCRALVCRHE KPSALLKGRT ACCHSETVV

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.