Genular: Defining Cellular Identity and Function

Details for: Tgfb3

Gene ID: 21809

Symbol: Tgfb3

Ensembl ID: ENSMUSG00000021253

Description: transforming growth factor, beta 3

Associated with

Elastic fibre formation
(R-MMU-1566948)
Extracellular matrix organization
(R-MMU-1474244)
Hemostasis
(R-MMU-109582)
Molecules associated with elastic fibres
(R-MMU-2129379)
Platelet activation, signaling and aggregation
(R-MMU-76002)
Platelet degranulation
(R-MMU-114608)
Response to elevated platelet cytosolic ca2+
(R-MMU-76005)
Signaling by tgf-beta receptor complex
(R-MMU-170834)
Signaling by tgfb family members
(R-MMU-9006936)
Signal transduction
(R-MMU-162582)
Tgf-beta receptor signaling activates smads
(R-MMU-2173789)
Animal organ morphogenesis
(GO:0009887)
Cell-cell junction organization
(GO:0045216)
Cell population proliferation
(GO:0008283)
Cell surface
(GO:0009986)
Cellular response to growth factor stimulus
(GO:0071363)
Collagen-containing extracellular matrix
(GO:0062023)
Cytokine activity
(GO:0005125)
Detection of hypoxia
(GO:0070483)
Embryo development
(GO:0009790)
Embryonic neurocranium morphogenesis
(GO:0048702)
Epithelial cell proliferation
(GO:0050673)
Extracellular matrix
(GO:0031012)
Extracellular region
(GO:0005576)
Extracellular space
(GO:0005615)
Face morphogenesis
(GO:0060325)
Filopodium assembly
(GO:0046847)
Gene expression
(GO:0010467)
Growth factor activity
(GO:0008083)
Identical protein binding
(GO:0042802)
Intracellular membrane-bounded organelle
(GO:0043231)
In utero embryonic development
(GO:0001701)
Lung alveolus development
(GO:0048286)
Mammary gland development
(GO:0030879)
Negative regulation of cell population proliferation
(GO:0008285)
Negative regulation of epithelial cell proliferation
(GO:0050680)
Negative regulation of macrophage cytokine production
(GO:0010936)
Negative regulation of neuron apoptotic process
(GO:0043524)
Negative regulation of transforming growth factor beta receptor signaling pathway
(GO:0030512)
Negative regulation of vascular associated smooth muscle cell proliferation
(GO:1904706)
Neuronal cell body
(GO:0043025)
Neuron apoptotic process
(GO:0051402)
Positive regulation of apoptotic process
(GO:0043065)
Positive regulation of cell division
(GO:0051781)
Positive regulation of cell population proliferation
(GO:0008284)
Positive regulation of collagen biosynthetic process
(GO:0032967)
Positive regulation of dna-templated transcription
(GO:0045893)
Positive regulation of epithelial to mesenchymal transition
(GO:0010718)
Positive regulation of filopodium assembly
(GO:0051491)
Positive regulation of gene expression
(GO:0010628)
Positive regulation of mapk cascade
(GO:0043410)
Positive regulation of protein secretion
(GO:0050714)
Positive regulation of smad protein signal transduction
(GO:0060391)
Positive regulation of stress fiber assembly
(GO:0051496)
Positive regulation of tight junction disassembly
(GO:1905075)
Positive regulation of transcription by rna polymerase ii
(GO:0045944)
Protein-containing complex binding
(GO:0044877)
Protein binding
(GO:0005515)
Regulation of cell population proliferation
(GO:0042127)
Regulation of epithelial to mesenchymal transition involved in endocardial cushion formation
(GO:1905005)
Response to estrogen
(GO:0043627)
Response to hypoxia
(GO:0001666)
Response to progesterone
(GO:0032570)
Roof of mouth development
(GO:0060021)
Secondary palate development
(GO:0062009)
Secretory granule
(GO:0030141)
T-tubule
(GO:0030315)
Transforming growth factor beta binding
(GO:0050431)
Transforming growth factor beta receptor binding
(GO:0005160)
Transforming growth factor beta receptor signaling pathway
(GO:0007179)
Type iii transforming growth factor beta receptor binding
(GO:0034714)
Type ii transforming growth factor beta receptor binding
(GO:0005114)
Type i transforming growth factor beta receptor binding
(GO:0034713)

Other Information

Proteins

Q3TRQ9_MOUSE
Q91YU7_MOUSE

Genular Protein ID: 3017826777

Symbol: Q3TRQ9_MOUSE

Name: N/A

UniProtKB Accession Codes:

Q3TRQ9

Database IDs:

Citations:

PubMed ID: 10349636

Title: High-efficiency full-length cDNA cloning.

PubMed ID: 10349636

DOI: 10.1016/S0076-6879(99)03004-9

PubMed ID: 11042159

Title: Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes.

PubMed ID: 11042159

DOI: 10.1101/gr.145100

PubMed ID: 11076861

Title: RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer.

PubMed ID: 11076861

DOI: 10.1101/gr.152600

PubMed ID: 11217851

Title: Functional annotation of a full-length mouse cDNA collection.

PubMed ID: 11217851

DOI: 10.1038/35055500

PubMed ID: 12466851

Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.

PubMed ID: 12466851

DOI: 10.1038/nature01266

PubMed ID: 16141073

Title: Antisense Transcription in the Mammalian Transcriptome.

PubMed ID: 16141073

DOI: 10.1126/science.1112009

Sequence Information:

Length: 351
Mass: 40423
Checksum: 7CBF8C37D5858E47
Sequence:

MTHVPYQVLA LYNSTRELLE EMHGEREEGC TQETSESEYY AKEIHKFDMI QGLAEHNELA 
VCPKGITSKV FRFNVSSVEK NGTNLFRAEF RVLRVPNPSS KRTEQRIELF QILRPDEHIA 
KQRYIGGKNL PTRGTAEWLS FDVTDTVREW LLRRESNLGL EISIHCPCHT FQPNGDILEN 
VHEVMEIKFK GVDNEDDHGR GDLGRLKKQK DHHNPHLILM MIPPHRLDSP GQGSQRKKRA 
LDTNYCFRNL EENCCVRPLY IDFRQDLGWK WVHEPKGYYA NFCSGPCPYL RSADTTHSTV 
LGLYNTLNPE ASASPCCVPQ DLEPLTILYY VGRTPKVEQL SNMVVKSCKC S

Genular Protein ID: 2300852930

Symbol: Q91YU7_MOUSE

Name: N/A

UniProtKB Accession Codes:

Q91YU7

Database IDs:

Citations:

PubMed ID: 10349636

Title: High-efficiency full-length cDNA cloning.

PubMed ID: 10349636

DOI: 10.1016/S0076-6879(99)03004-9

PubMed ID: 11042159

Title: Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes.

PubMed ID: 11042159

DOI: 10.1101/gr.145100

PubMed ID: 11076861

Title: RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer.

PubMed ID: 11076861

DOI: 10.1101/gr.152600

PubMed ID: 11217851

Title: Functional annotation of a full-length mouse cDNA collection.

PubMed ID: 11217851

DOI: 10.1038/35055500

PubMed ID: 12466851

Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.

PubMed ID: 12466851

DOI: 10.1038/nature01266

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 16141073

Title: Antisense Transcription in the Mammalian Transcriptome.

PubMed ID: 16141073

DOI: 10.1126/science.1112009

PubMed ID: 19468303

Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.

PubMed ID: 19468303

DOI: 10.1371/journal.pbio.1000112

Sequence Information:

Length: 412
Mass: 47144
Checksum: F3EB65D046DF32AD
Sequence:

MKMHLQRALV VLALLNLATI SLSLSTCTTL DFGHIKKKRV EAIRGQILSK LRLTSPPEPS 
VMTHVPYQVL ALYNSTRELL EEMHGEREEG CTQETSESEY YAKEIHKFDM IQGLAEHNEL 
AVCPKGITSK VFRFNVSSVE KNGTNLFRAE FRVLRVPNPS SKRTEQRIEL FQILRPDEHI 
AKQRYIGGKN LPTRGTAEWL SFDVTDTVRE WLLRRESNLG LEISIHCPCH TFQPNGDILE 
NVHEVMEIKF KGVDNEDDHG RGDLGRLKKQ KDHHNPHLIL MMIPPHRLDS PGQGSQRKKR 
ALDTNYCFRN LEENCCVRPL YIDFRQDLGW KWVHEPKGYY ANFCSGPCPY LRSADTTHST 
VLGLYNTLNP EASASPCCVP QDLEPLTILY YVGRTPKVEQ LSNMVVKSCK CS

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Tgfb3

Associated with

Other Information

High-efficiency full-length cDNA cloning. PubMed ID: 10349636

Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes. PubMed ID: 11042159

RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer. PubMed ID: 11076861

Functional annotation of a full-length mouse cDNA collection. PubMed ID: 11217851

Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. PubMed ID: 12466851

Antisense Transcription in the Mammalian Transcriptome. PubMed ID: 16141073

High-efficiency full-length cDNA cloning. PubMed ID: 10349636

Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes. PubMed ID: 11042159

RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer. PubMed ID: 11076861

Functional annotation of a full-length mouse cDNA collection. PubMed ID: 11217851

Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. PubMed ID: 12466851

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Antisense Transcription in the Mammalian Transcriptome. PubMed ID: 16141073

Lineage-specific biology revealed by a finished genome assembly of the mouse. PubMed ID: 19468303

Database document:

PubMed ID: 10349636

PubMed ID: 11042159

PubMed ID: 11076861

PubMed ID: 11217851

PubMed ID: 12466851

PubMed ID: 16141073

PubMed ID: 10349636

PubMed ID: 11042159

PubMed ID: 11076861

PubMed ID: 11217851

PubMed ID: 12466851

PubMed ID: 15489334

PubMed ID: 16141073

PubMed ID: 19468303