Details for: Tgm2

Gene ID: 21817

Symbol: Tgm2

Ensembl ID: ENSMUSG00000037820

Description: transglutaminase 2, C polypeptide

Associated with

Other Information

Genular Protein ID: 572408500

Symbol: TGM2_MOUSE

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 1670766

Title: Isolation and characterization of cDNA clones to mouse macrophage and human endothelial cell tissue transglutaminases.

PubMed ID: 1670766

DOI: 10.1016/s0021-9258(18)52460-1

PubMed ID: 10334875

Title: Organization and chromosomal mapping of mouse Gh/tissue transglutaminase gene (Tgm2).

PubMed ID: 10334875

DOI: 10.1006/abbi.1999.1189

PubMed ID: 10200571

Title: Mapping and sequencing of the murine 'tissue' transglutaminase (Tgm2) gene: absence of mutations in MRLlpr/lpr mice.

PubMed ID: 10200571

DOI: 10.1038/sj.cdd.4400494

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 19468303

Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.

PubMed ID: 19468303

DOI: 10.1371/journal.pbio.1000112

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 8626785

Title: Identification and characterization of a versatile retinoid response element (retinoic acid receptor response element-retinoid X receptor response element) in the mouse tissue transglutaminase gene promoter.

PubMed ID: 8626785

DOI: 10.1074/jbc.271.8.4355

PubMed ID: 11274171

Title: Targeted inactivation of Gh/tissue transglutaminase II.

PubMed ID: 11274171

DOI: 10.1074/jbc.m010846200

PubMed ID: 11113189

Title: Gene disruption of tissue transglutaminase.

PubMed ID: 11113189

DOI: 10.1128/mcb.21.1.148-155.2001

PubMed ID: 12205028

Title: Role of transglutaminase 2 in glucose tolerance: knockout mice studies and a putative mutation in a MODY patient.

PubMed ID: 12205028

DOI: 10.1096/fj.01-0689com

PubMed ID: 12810961

Title: Transglutaminase 2-/- mice reveal a phagocytosis-associated crosstalk between macrophages and apoptotic cells.

PubMed ID: 12810961

DOI: 10.1073/pnas.0832466100

PubMed ID: 15905580

Title: Transglutaminase type II is a key element in the regulation of the anti-inflammatory response elicited by apoptotic cell engulfment.

PubMed ID: 15905580

DOI: 10.4049/jimmunol.174.11.7330

PubMed ID: 19644512

Title: The adenine nucleotide translocator 1 acts as a type 2 transglutaminase substrate: implications for mitochondrial-dependent apoptosis.

PubMed ID: 19644512

DOI: 10.1038/cdd.2009.100

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 20489165

Title: Decreased S-nitrosylation of tissue transglutaminase contributes to age-related increases in vascular stiffness.

PubMed ID: 20489165

DOI: 10.1161/circresaha.109.215228

PubMed ID: 23806337

Title: SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways.

PubMed ID: 23806337

DOI: 10.1016/j.molcel.2013.06.001

PubMed ID: 32116663

Title: Role of TG2-mediated SERCA2 serotonylation on hypoxic pulmonary vein remodeling.

PubMed ID: 32116663

DOI: 10.3389/fphar.2019.01611

Sequence Information:

  • Length: 686
  • Mass: 77061
  • Checksum: 9B64B074D3F837DE
  • Sequence:
  • MAEELLLERC DLEIQANGRD HHTADLCQEK LVLRRGQRFR LTLYFEGRGY EASVDSLTFG 
    AVTGPDPSEE AGTKARFSLS DNVEEGSWSA SVLDQQDNVL SLQLCTPANA PIGLYRLSLE 
    ASTGYQGSSF VLGHFILLYN AWCPADDVYL DSEEERREYV LTQQGFIYQG SVKFIKSVPW 
    NFGQFEDGIL DTCLMLLDMN PKFLKNRSRD CSRRSSPIYV GRVVSAMVNC NDDQGVLLGR 
    WDNNYGDGIS PMAWIGSVDI LRRWKEHGCQ QVKYGQCWVF AAVACTVLRC LGIPTRVVTN 
    YNSAHDQNSN LLIEYFRNEF GELESNKSEM IWNFHCWVES WMTRPDLQPG YEGWQAIDPT 
    PQEKSEGTYC CGPVSVRAIK EGDLSTKYDA PFVFAEVNAD VVDWIRQEDG SVLKSINRSL 
    VVGQKISTKS VGRDDREDIT HTYKYPEGSP EEREVFTKAN HLNKLAEKEE TGVAMRIRVG 
    DSMSMGNDFD VFAHIGNDTS ETRECRLLLC ARTVSYNGVL GPECGTEDIN LTLDPYSENS 
    IPLRILYEKY SGCLTESNLI KVRGLLIEPA ANSYLLAERD LYLENPEIKI RVLGEPKQNR 
    KLVAEVSLKN PLSDPLYDCI FTVEGAGLTK EQKSVEVSDP VPAGDLVKAR VDLFPTDIGL 
    HKLVVNFQCD KLKSVKGYRN VIIGPA

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.