Genular: Defining Cellular Identity and Function

Details for: Thbd

Gene ID: 21824

Symbol: Thbd

Ensembl ID: ENSMUSG00000074743

Description: thrombomodulin

Associated with

Cell surface interactions at the vascular wall
(R-MMU-202733)
Common pathway of fibrin clot formation
(R-MMU-140875)
Formation of fibrin clot (clotting cascade)
(R-MMU-140877)
Apicolateral plasma membrane
(GO:0016327)
Blood coagulation
(GO:0007596)
Calcium ion binding
(GO:0005509)
Cell surface
(GO:0009986)
Embryo development
(GO:0009790)
External side of plasma membrane
(GO:0009897)
Extracellular space
(GO:0005615)
Female pregnancy
(GO:0007565)
Hemostasis
(GO:0007599)
Membrane
(GO:0016020)
Negative regulation of coagulation
(GO:0050819)
Plasma membrane
(GO:0005886)
Serine-type endopeptidase complex
(GO:1905370)
Transmembrane signaling receptor activity
(GO:0004888)
Vacuolar membrane
(GO:0005774)

Other Information

Proteins

Thrombomodulin

Genular Protein ID: 2913507100

Symbol: TRBM_MOUSE

Name: Thrombomodulin

UniProtKB Accession Codes:

P15306

Database IDs:

Citations:

PubMed ID: 2536925

Title: Sequence of a cDNA for mouse thrombomodulin and comparison of the predicted mouse and human amino acid sequences.

PubMed ID: 2536925

DOI: 10.1093/nar/17.2.802

PubMed ID: 2844823

Title: The structure and function of mouse thrombomodulin. Phorbol myristate acetate stimulates degradation and synthesis of thrombomodulin without affecting mRNA levels in hemangioma cells.

PubMed ID: 2844823

DOI: 10.1016/s0021-9258(19)37661-6

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 19656770

Title: The mouse C2C12 myoblast cell surface N-linked glycoproteome: identification, glycosite occupancy, and membrane orientation.

PubMed ID: 19656770

DOI: 10.1074/mcp.m900195-mcp200

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

Sequence Information:

Length: 577
Mass: 61868
Checksum: B20E50B0FE745014
Sequence:

MLGIFFLGVL APASLGLSAL AKLQPTGSQC VEHECFALFQ GPATFLDASQ ACQRLQGHLM 
TVRSSVAADV ISLLLSQSSM DLGPWIGLQL PQGCDDPVHL GPLRGFQWVT GDNHTSYSRW 
ARPNDQTAPL CGPLCVTVST ATEAAPGEPA WEEKPCETET QGFLCEFYFT ASCRPLTVNT 
RDPEAAHISS TYNTPFGVSG ADFQTLPVGS SAAVEPLGLE LVCRAPPGTS EGHWAWEATG 
AWNCSVENGG CEYLCNRSTN EPRCLCPRDM DLQADGRSCA RPVVQSCNEL CEHFCVSNAE 
VPGSYSCMCE TGYQLAADGH RCEDVDDCKQ GPNPCPQLCV NTKGGFECFC YDGYELVDGE 
CVELLDPCFG SNCEFQCQPV SPTDYRCICA PGFAPKPDEP HKCEMFCNET SCPADCDPNS 
PTVCECPEGF ILDEGSVCTD IDECSQGECF TSECRNFPGS YECICGPDTA LAGQISKDCD 
PIPVREDTKE EEGSGEPPVS PTPGSPTGPP SARPVHSGVL IGISIASLSL VVALLALLCH 
LRKKQGAARA ELEYKCASSA KEVVLQHVRT DRTLQKF

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Thbd

Associated with

Other Information

Sequence of a cDNA for mouse thrombomodulin and comparison of the predicted mouse and human amino acid sequences. PubMed ID: 2536925

The structure and function of mouse thrombomodulin. Phorbol myristate acetate stimulates degradation and synthesis of thrombomodulin without affecting mRNA levels in hemangioma cells. PubMed ID: 2844823

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334