Genular: Defining Cellular Identity and Function

Details for: Thbs4

Gene ID: 21828

Symbol: Thbs4

Ensembl ID: ENSMUSG00000021702

Description: thrombospondin 4

Associated with

Signaling by pdgf
(R-MMU-186797)
Signaling by receptor tyrosine kinases
(R-MMU-9006934)
Signal transduction
(R-MMU-162582)
Basement membrane
(GO:0005604)
Behavioral response to pain
(GO:0048266)
Calcium ion binding
(GO:0005509)
Cell adhesion
(GO:0007155)
Collagen-containing extracellular matrix
(GO:0062023)
Collagen binding
(GO:0005518)
Endoplasmic reticulum
(GO:0005783)
Endothelial cell-cell adhesion
(GO:0071603)
Extracellular matrix structural constituent
(GO:0005201)
Extracellular region
(GO:0005576)
Extracellular space
(GO:0005615)
Fibronectin binding
(GO:0001968)
Growth factor activity
(GO:0008083)
Heparin binding
(GO:0008201)
Identical protein binding
(GO:0042802)
Integrin binding
(GO:0005178)
Laminin-1 binding
(GO:0043237)
Myoblast migration
(GO:0051451)
Nervous system development
(GO:0007399)
Neuromuscular junction
(GO:0031594)
Neuron projection morphogenesis
(GO:0048812)
Positive regulation of cell division
(GO:0051781)
Positive regulation of endothelial cell proliferation
(GO:0001938)
Positive regulation of neutrophil chemotaxis
(GO:0090023)
Positive regulation of peptidyl-tyrosine phosphorylation
(GO:0050731)
Protein binding
(GO:0005515)
Regulation of tissue remodeling
(GO:0034103)
Response to endoplasmic reticulum stress
(GO:0034976)
Response to unfolded protein
(GO:0006986)
Sarcoplasmic reticulum
(GO:0016529)
Tissue remodeling
(GO:0048771)

Other Information

Proteins

Thrombospondin-4

Genular Protein ID: 1791262920

Symbol: TSP4_MOUSE

Name: Thrombospondin-4

UniProtKB Accession Codes:

Q9Z1T2 Q9QYS3 Q9WUE0

Database IDs:

Citations:

PubMed ID: 10501972

Title: The thrombospondin-4 gene.

PubMed ID: 10501972

DOI: 10.1007/s003359901149

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 20884877

Title: Thrombospondin-4 regulates vascular inflammation and atherogenesis.

PubMed ID: 20884877

DOI: 10.1161/circresaha.110.232371

PubMed ID: 22034490

Title: Thrombospondin-4 is required for stretch-mediated contractility augmentation in cardiac muscle.

PubMed ID: 22034490

DOI: 10.1161/circresaha.111.256743

PubMed ID: 22682248

Title: A thrombospondin-dependent pathway for a protective ER stress response.

PubMed ID: 22682248

DOI: 10.1016/j.cell.2012.03.050

PubMed ID: 22362893

Title: Thrombospondin-4 regulates fibrosis and remodeling of the myocardium in response to pressure overload.

PubMed ID: 22362893

DOI: 10.1096/fj.11-190728

PubMed ID: 22745497

Title: Thrombospondin-4 contributes to spinal sensitization and neuropathic pain states.

PubMed ID: 22745497

DOI: 10.1523/jneurosci.6494-11.2012

PubMed ID: 23615612

Title: Protective astrogenesis from the SVZ niche after injury is controlled by Notch modulator Thbs4.

PubMed ID: 23615612

DOI: 10.1038/nature12069

Sequence Information:

Length: 963
Mass: 106366
Checksum: B8BA83B84F489FB1
Sequence:

MPAPRAAAAA FLLLHLVLQP WQRTSAQATP QVFDLLPSSS QRLNPSALQP VLTDPTLHEV 
YLISTFKLQS KSSATIFGLY SSSDNSKYFE FTVMGRLNKA ILRYLKNDGK IHLVVFNNLQ 
LADGRRHRVL LRLSNLQRGD GSVELYLDCA QADSVRNLPR AFSGLTQNPE SIELRTFQRK 
PQDFLEELKL VVRGSLFQVA SLQDCFLQQS EPLAATSTGD FNRQFLGQMT QLNQLLGEVK 
DLLRQQVKET SFLRNTIAEC QACGPLSFQS PTPNTLVPIA PPAPPTRPTR HCDSSPCFRG 
VRCTDTRDGF QCGPCPDGYT GNGITCSDVD ECKYHPCYPG VRCVNLAPGF RCDACPVGFT 
GPMVQGVGIN FAKTNKQVCT DVDECQNGAC VLNSICINTL GSYRCGPCKP GYTGDQTRGC 
KTERSCRNPE QNPCSVHAQC IEERQGDVTC VCGVGWAGDG YVCGKDVDID SYPDEELPCS 
ARNCKKDNCK YVPNSGQEDA DRDGIGDACD EDADGDGILN EQDNCVLTHN IDQRNSDKDI 
FGDACDNCRM VLNNDQKDTD GDGRGDACDD DMDGDGIKNI LDNCPRVPNR DQQDRDGDDV 
GDACDSCPDV SNPNQSDVDN DLVGDSCDTN QDSDGDGHQD STDNCPTVIN SSQLDTDKDG 
IGDECDDDDD NDGIPDLVPP GPDNCRLVPN PAQEDSNNDG VGDICEADFD QDQVIDHIDV 
CPENAEITLT DFRAYQTVVL DPEGDAQIDP NWVVLNQGME IVQTMNSDPG LAVGYTAFNG 
VDFEGTFHVN TQTDDDYAGF IFGYQDSSSF YVVMWKQTEQ TYWQATPFRA VAEPGIQLKA 
VKSKTGPGEH LRNSLWHTGD TSDQVRLLWK DSRNVGWKDK VSYRWFLQHR PQVGYIRVRF 
YEGSELVADS GVTIDTTMRG GRLGVFCFSQ ENIIWSNLKY RCNDTIPEDF QEFQTQSFDR 
LDN

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Thbs4

Associated with

Other Information

The thrombospondin-4 gene. PubMed ID: 10501972

A tissue-specific atlas of mouse protein phosphorylation and expression. PubMed ID: 21183079

Thrombospondin-4 regulates vascular inflammation and atherogenesis. PubMed ID: 20884877

Thrombospondin-4 is required for stretch-mediated contractility augmentation in cardiac muscle. PubMed ID: 22034490

A thrombospondin-dependent pathway for a protective ER stress response. PubMed ID: 22682248

Thrombospondin-4 regulates fibrosis and remodeling of the myocardium in response to pressure overload. PubMed ID: 22362893

Thrombospondin-4 contributes to spinal sensitization and neuropathic pain states. PubMed ID: 22745497

Protective astrogenesis from the SVZ niche after injury is controlled by Notch modulator Thbs4. PubMed ID: 23615612