Genular: Defining Cellular Identity and Function

Details for: Thrb

Gene ID: 21834

Symbol: Thrb

Ensembl ID: ENSMUSG00000021779

Description: thyroid hormone receptor beta

Associated with

Gene expression (transcription)
(R-MMU-74160)
Generic transcription pathway
(R-MMU-212436)
Metabolism of proteins
(R-MMU-392499)
Nuclear receptor transcription pathway
(R-MMU-383280)
Post-translational protein modification
(R-MMU-597592)
Rna polymerase ii transcription
(R-MMU-73857)
Sumo e3 ligases sumoylate target proteins
(R-MMU-3108232)
Sumoylation
(R-MMU-2990846)
Sumoylation of intracellular receptors
(R-MMU-4090294)
Animal organ morphogenesis
(GO:0009887)
Cell differentiation
(GO:0030154)
Cellular response to thyroid hormone stimulus
(GO:0097067)
Chromatin binding
(GO:0003682)
Chromatin dna binding
(GO:0031490)
Dna-binding transcription factor activity
(GO:0003700)
Dna binding
(GO:0003677)
Double-stranded dna binding
(GO:0003690)
Enzyme binding
(GO:0019899)
Female courtship behavior
(GO:0008050)
Identical protein binding
(GO:0042802)
Metal ion binding
(GO:0046872)
Mrna transcription by rna polymerase ii
(GO:0042789)
Negative regulation of dna-templated transcription
(GO:0045892)
Negative regulation of female receptivity
(GO:0007621)
Negative regulation of transcription by rna polymerase ii
(GO:0000122)
Nuclear body
(GO:0016604)
Nuclear receptor activity
(GO:0004879)
Nucleus
(GO:0005634)
Positive regulation of cell population proliferation
(GO:0008284)
Positive regulation of chondrocyte differentiation
(GO:0032332)
Positive regulation of ossification
(GO:0045778)
Positive regulation of thyroid hormone mediated signaling pathway
(GO:0002157)
Positive regulation of transcription by rna polymerase ii
(GO:0045944)
Protein binding
(GO:0005515)
Regulation of cholesterol metabolic process
(GO:0090181)
Regulation of dna-templated transcription
(GO:0006355)
Regulation of heart contraction
(GO:0008016)
Regulation of lipid metabolic process
(GO:0019216)
Regulation of transcription by rna polymerase ii
(GO:0006357)
Regulation of triglyceride metabolic process
(GO:0090207)
Retinal cone cell apoptotic process
(GO:0097474)
Retinal cone cell development
(GO:0046549)
Retinoic acid receptor signaling pathway
(GO:0048384)
Rna polymerase ii cis-regulatory region sequence-specific dna binding
(GO:0000978)
Rna polymerase ii transcription regulator complex
(GO:0090575)
Sensory perception of sound
(GO:0007605)
Sequence-specific dna binding
(GO:0043565)
Sequence-specific double-stranded dna binding
(GO:1990837)
Thyroid hormone binding
(GO:0070324)
Thyroid hormone mediated signaling pathway
(GO:0002154)
Transcription coactivator binding
(GO:0001223)
Type i pneumocyte differentiation
(GO:0060509)
Zinc ion binding
(GO:0008270)

Other Information

Proteins

Thyroid hormone receptor beta
Q3UZT5_MOUSE

Genular Protein ID: 879341454

Symbol: THB_MOUSE

Name: Thyroid hormone receptor beta

UniProtKB Accession Codes:

P37242 P37244 Q0VDR8 Q3TY80

Database IDs:

Citations:

PubMed ID: 1944303

Title: Isolation and characterization of mouse complementary DNAs encoding alpha and beta thyroid hormone receptors from thyrotrope cells: the mouse pituitary-specific beta 2 isoform differs at the amino terminus from the corresponding species from rat pituitary tumor cells.

PubMed ID: 1944303

DOI: 10.1210/mend-5-8-1049

PubMed ID: 7708051

Title: Structural and functional characterization of the genomic locus encoding the murine beta 2 thyroid hormone receptor.

PubMed ID: 7708051

DOI: 10.1210/mend.8.12.7708051

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 9405624

Title: Cloning and characterization of a corepressor and potential component of the nuclear hormone receptor repression complex.

PubMed ID: 9405624

DOI: 10.1073/pnas.94.26.14400

Sequence Information:

Length: 461
Mass: 52630
Checksum: 99089194FC3E6B33
Sequence:

MTPNSMTENG LPAWDKQKPR PDRGQDWKLV GMSEACLHRK SHVERRGALK NEQTSPHLIQ 
ATWTSSIFHL DPDDVNDQSI SSAQTFQTEE KKCKGYIPSY LDKDELCVVC GDKATGYHYR 
CITCEGCKGF FRRTIQKSLH PSYSCKYEGK CIIDKVTRNQ CQECRFKKCI YVGMATDLVL 
DDSKRLAKRK LIEENREKRR REELQKSIGH KPEPTDEEWE LIKTVTEAHV ATNAQGSHWK 
QKRKFLPEDI GQAPIVNAPE GGKVDLEAFS HFTKIITPAI TRVVDFAKKL PMFCELPCED 
QIILLKGCCM EIMSLRAAVR YDPDSETLTL NGEMAVTRGQ LKNGGLGVVS DAIFDLGMSL 
SSFNLDDTEV ALLQAVLLMS SDRPGLACVE RIEKYQDSFL LAFEHYINYR KHHVTHFWPK 
LLMKVTDLRM IGACHASRFL HMKVECPTEL FPPLFLEVFE D

Genular Protein ID: 503881089

Symbol: Q3UZT5_MOUSE

Name: N/A

UniProtKB Accession Codes:

Q3UZT5

Database IDs:

Citations:

PubMed ID: 10349636

Title: High-efficiency full-length cDNA cloning.

PubMed ID: 10349636

DOI: 10.1016/S0076-6879(99)03004-9

PubMed ID: 11042159

Title: Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes.

PubMed ID: 11042159

DOI: 10.1101/gr.145100

PubMed ID: 11076861

Title: RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer.

PubMed ID: 11076861

DOI: 10.1101/gr.152600

PubMed ID: 11217851

Title: Functional annotation of a full-length mouse cDNA collection.

PubMed ID: 11217851

DOI: 10.1038/35055500

PubMed ID: 12466851

Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.

PubMed ID: 12466851

DOI: 10.1038/nature01266

PubMed ID: 16141073

Title: Antisense Transcription in the Mammalian Transcriptome.

PubMed ID: 16141073

DOI: 10.1126/science.1112009

Sequence Information:

Length: 385
Mass: 43959
Checksum: 8B676D6B3B148CC7
Sequence:

AEEKPFPQVQ SPPHSQKKGY IPSYLDKDEL CVVCGDKATG YHYRCITCEG CKGFFRRTIQ 
KSLHPSYSCK YEGKCIIDKV TRNQCQECRF KKCIYVGMAT DLVLDDSKRL AKRKLIEENR 
EKRRREELQK SIGHKPEPTD EEWELIKTVT EAHVATNAQG SHWKQKRKFL PEDIGQAPIV 
NAPEGGKVDL EAFSHFTKII TPAITRVVDF AKKLPMFCEL PCEDQIILLK GCCMEIMSLR 
AAVRYDPDSE TLTLNGEMAV TRGQLKNGGL GVVSDAIFDL GMSLSSFNLD DTEVALLQAV 
LLMSSDRPGL ACVERIEKYQ DSFLLAFEHY INYRKHHVTH FWPKLLMKVT DLRMIGACHA 
SRFLHMKVEC PTELFPPLFL EVFED

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Thrb

Associated with

Other Information

Isolation and characterization of mouse complementary DNAs encoding alpha and beta thyroid hormone receptors from thyrotrope cells: the mouse pituitary-specific beta 2 isoform differs at the amino terminus from the corresponding species from rat pituitary tumor cells. PubMed ID: 1944303

Structural and functional characterization of the genomic locus encoding the murine beta 2 thyroid hormone receptor. PubMed ID: 7708051

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Cloning and characterization of a corepressor and potential component of the nuclear hormone receptor repression complex. PubMed ID: 9405624

High-efficiency full-length cDNA cloning. PubMed ID: 10349636

Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes. PubMed ID: 11042159

RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer. PubMed ID: 11076861

Functional annotation of a full-length mouse cDNA collection. PubMed ID: 11217851

Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. PubMed ID: 12466851

Antisense Transcription in the Mammalian Transcriptome. PubMed ID: 16141073