Details for: Trim28

Gene ID: 21849

Symbol: Trim28

Ensembl ID: ENSMUSG00000005566

Description: tripartite motif-containing 28

Associated with

Other Information

Genular Protein ID: 4086581205

Symbol: TIF1B_MOUSE

Name: E3 SUMO-protein ligase TRIM28

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 8978696

Title: A possible involvement of TIF1 alpha and TIF1 beta in the epigenetic control of transcription by nuclear receptors.

PubMed ID: 8978696

PubMed ID: 8986806

Title: A novel member of the RING finger family, KRIP-1, associates with the KRAB-A transcriptional repressor domain of zinc finger proteins.

PubMed ID: 8986806

DOI: 10.1073/pnas.93.26.15299

PubMed ID: 10940561

Title: Correlation of the exon/intron organization to the conserved domains of the mouse transcriptional corepressor TIF1beta.

PubMed ID: 10940561

DOI: 10.1016/s0378-1119(00)00263-8

PubMed ID: 11331580

Title: The tripartite motif family identifies cell compartments.

PubMed ID: 11331580

DOI: 10.1093/emboj/20.9.2140

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 9742105

Title: Coactivator TIF1beta interacts with transcription factor C/EBPbeta and glucocorticoid receptor to induce alpha1-acid glycoprotein gene expression.

PubMed ID: 9742105

DOI: 10.1128/mcb.18.10.5880

PubMed ID: 10562550

Title: Interaction with members of the heterochromatin protein 1 (HP1) family and histone deacetylation are differentially involved in transcriptional silencing by members of the TIF1 family.

PubMed ID: 10562550

DOI: 10.1093/emboj/18.22.6385

PubMed ID: 10330177

Title: KAP-1 corepressor protein interacts and colocalizes with heterochromatic and euchromatic HP1 proteins: a potential role for Kruppel-associated box-zinc finger proteins in heterochromatin-mediated gene silencing.

PubMed ID: 10330177

DOI: 10.1128/mcb.19.6.4366

PubMed ID: 11154279

Title: Sequence-specific transcriptional repression by KS1, a multiple-zinc-finger-Kruppel-associated box protein.

PubMed ID: 11154279

DOI: 10.1128/mcb.21.3.928-939.2001

PubMed ID: 12154074

Title: Cell differentiation induces TIF1beta association with centromeric heterochromatin via an HP1 interaction.

PubMed ID: 12154074

DOI: 10.1242/jcs.115.17.3439

PubMed ID: 15345747

Title: Phosphoproteomic analysis of the developing mouse brain.

PubMed ID: 15345747

DOI: 10.1074/mcp.m400085-mcp200

PubMed ID: 16452087

Title: Comprehensive identification of phosphorylation sites in postsynaptic density preparations.

PubMed ID: 16452087

DOI: 10.1074/mcp.t500041-mcp200

PubMed ID: 17242355

Title: Large-scale phosphorylation analysis of mouse liver.

PubMed ID: 17242355

DOI: 10.1073/pnas.0609836104

PubMed ID: 19144319

Title: The phagosomal proteome in interferon-gamma-activated macrophages.

PubMed ID: 19144319

DOI: 10.1016/j.immuni.2008.11.006

PubMed ID: 19321449

Title: TIF1beta/KAP-1 is a coactivator of the orphan nuclear receptor NGFI-B/Nur77.

PubMed ID: 19321449

DOI: 10.1074/jbc.m809023200

PubMed ID: 19131326

Title: Large scale localization of protein phosphorylation by use of electron capture dissociation mass spectrometry.

PubMed ID: 19131326

DOI: 10.1074/mcp.m800451-mcp200

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 20164836

Title: Proviral silencing in embryonic stem cells requires the histone methyltransferase ESET.

PubMed ID: 20164836

DOI: 10.1038/nature08858

PubMed ID: 22110054

Title: TRIM28 is required by the mouse KRAB domain protein ZFP568 to control convergent extension and morphogenesis of extra-embryonic tissues.

PubMed ID: 22110054

DOI: 10.1242/dev.072546

PubMed ID: 21518874

Title: Histone chaperone Spt6 is required for class switch recombination but not somatic hypermutation.

PubMed ID: 21518874

DOI: 10.1073/pnas.1104423108

PubMed ID: 23806337

Title: SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways.

PubMed ID: 23806337

DOI: 10.1016/j.molcel.2013.06.001

PubMed ID: 24413057

Title: Temporal orchestration of repressive chromatin modifiers by circadian clock Period complexes.

PubMed ID: 24413057

DOI: 10.1038/nsmb.2746

PubMed ID: 24463520

Title: Citrullination regulates pluripotency and histone H1 binding to chromatin.

PubMed ID: 24463520

DOI: 10.1038/nature12942

PubMed ID: 25247314

Title: SIRT6 represses LINE1 retrotransposons by ribosylating KAP1 but this repression fails with stress and age.

PubMed ID: 25247314

DOI: 10.1038/ncomms6011

PubMed ID: 27123980

Title: USP7 and TDP-43: pleiotropic regulation of cryptochrome protein stability paces the oscillation of the mammalian circadian clock.

PubMed ID: 27123980

DOI: 10.1371/journal.pone.0154263

PubMed ID: 27658112

Title: The Transcriptional Repressive Activity of KRAB Zinc Finger Proteins Does Not Correlate with Their Ability to Recruit TRIM28.

PubMed ID: 27658112

DOI: 10.1371/journal.pone.0163555

PubMed ID: 30017584

Title: MRI is a DNA damage response adaptor during classical non-homologous end joining.

PubMed ID: 30017584

DOI: 10.1016/j.molcel.2018.06.018

Sequence Information:

  • Length: 834
  • Mass: 88847
  • Checksum: DE87AAA5DC67BB8B
  • Sequence:
  • MAASAAATAA ASAATAASAA SGSPGSGEGS AGGEKRPAAS SAAAASAAAS SPAGGGGEAQ 
    ELLEHCGVCR ERLRPERDPR LLPCLHSACS ACLGPATPAA ANNSGDGGSA GDGAMVDCPV 
    CKQQCYSKDI VENYFMRDSG SKASSDSQDA NQCCTSCEDN APATSYCVEC SEPLCETCVE 
    AHQRVKYTKD HTVRSTGPAK TRDGERTVYC NVHKHEPLVL FCESCDTLTC RDCQLNAHKD 
    HQYQFLEDAV RNQRKLLASL VKRLGDKHAT LQKNTKEVRS SIRQVSDVQK RVQVDVKMAI 
    LQIMKELNKR GRVLVNDAQK VTEGQQERLE RQHWTMTKIQ KHQEHILRFA SWALESDNNT 
    ALLLSKKLIY FQLHRALKMI VDPVEPHGEM KFQWDLNAWT KSAEAFGKIV AERPGTNSTG 
    PGPMAPPRAP GPLSKQGSGS SQPMEVQEGY GFGSDDPYSS AEPHVSGMKR SRSGEGEVSG 
    LLRKVPRVSL ERLDLDLTSD SQPPVFKVFP GSTTEDYNLI VIERGAAAAA AGQAGTVPPG 
    APGAPPLPGM AIVKEEETEA AIGAPPAAPE GPETKPVLMP LTEGPGAEGP RLASPSGSTS 
    SGLEVVAPEV TSAPVSGPGI LDDSATICRV CQKPGDLVMC NQCEFCFHLD CHLPALQDVP 
    GEEWSCSLCH VLPDLKEEDG SLSLDGADST GVVAKLSPAN QRKCERVLLA LFCHEPCRPL 
    HQLATDSTFS MEQPGGTLDL TLIRARLQEK LSPPYSSPQE FAQDVGRMFK QFNKLTEDKA 
    DVQSIIGLQR FFETRMNDAF GDTKFSAVLV EPPPLNLPSA GLSSQELSGP GDGP

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.