Genular: Defining Cellular Identity and Function

Details for: Tkt

Gene ID: 21881

Symbol: Tkt

Ensembl ID: ENSMUSG00000021957

Description: transketolase

Associated with

Insulin effects increased synthesis of xylulose-5-phosphate
(R-MMU-163754)
Integration of energy metabolism
(R-MMU-163685)
Metabolism
(R-MMU-1430728)
Metabolism of carbohydrates
(R-MMU-71387)
Pentose phosphate pathway
(R-MMU-71336)
Calcium ion binding
(GO:0005509)
Carbohydrate binding
(GO:0030246)
Catalytic activity
(GO:0003824)
Cytosol
(GO:0005829)
Endoplasmic reticulum membrane
(GO:0005789)
Glyceraldehyde-3-phosphate biosynthetic process
(GO:0046166)
Magnesium ion binding
(GO:0000287)
Metal ion binding
(GO:0046872)
Monosaccharide binding
(GO:0048029)
Myelin sheath
(GO:0043209)
Nuclear body
(GO:0016604)
Nucleoplasm
(GO:0005654)
Pentose-phosphate shunt
(GO:0006098)
Pentose-phosphate shunt, non-oxidative branch
(GO:0009052)
Peroxisome
(GO:0005777)
Protein homodimerization activity
(GO:0042803)
Regulation of growth
(GO:0040008)
Thiamine pyrophosphate binding
(GO:0030976)
Transferase activity
(GO:0016740)
Transketolase activity
(GO:0004802)
Xylulose 5-phosphate biosynthetic process
(GO:1901159)

Other Information

Proteins

Transketolase

Genular Protein ID: 2951447844

Symbol: TKT_MOUSE

Name: Transketolase

UniProtKB Accession Codes:

P40142 Q3U7Y1 Q3UK62 Q545A1 Q9ESA0

Database IDs:

Citations:

PubMed ID: 8617775

Title: Amplification of the transketolase gene in desensitization-resistant mutant Y1 mouse adrenocortical tumor cells.

PubMed ID: 8617775

DOI: 10.1074/jbc.271.9.4993

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 9521875

Title: The mouse transketolase (TKT) gene: cloning, characterization, and functional promoter analysis.

PubMed ID: 9521875

DOI: 10.1006/geno.1997.5187

PubMed ID: 15592455

Title: Immunoaffinity profiling of tyrosine phosphorylation in cancer cells.

PubMed ID: 15592455

DOI: 10.1038/nbt1046

PubMed ID: 18034455

Title: Large-scale identification and evolution indexing of tyrosine phosphorylation sites from murine brain.

PubMed ID: 18034455

DOI: 10.1021/pr0701254

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 23806337

Title: SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways.

PubMed ID: 23806337

DOI: 10.1016/j.molcel.2013.06.001

Sequence Information:

Length: 623
Mass: 67630
Checksum: 870045AD5C58FA09
Sequence:

MEGYHKPDQQ KLQALKDTAN RLRISSIQAT TAAGSGHPTS CCSAAEIMAV LFFHTMRYKA 
LDPRNPHNDR FVLSKGHAAP ILYAVWAEAG FLPEAELLNL RKISSDLDGH PVPKQAFTDV 
ATGSLGQGLG AACGMAYTGK YFDKASYRVY CMLGDGEVSE GSVWEAMAFA GIYKLDNLVA 
IFDINRLGQS DPAPLQHQVD IYQKRCEAFG WHTIIVDGHS VEELCKAFGQ AKHQPTAIIA 
KTFKGRGITG IEDKEAWHGK PLPKNMAEQI IQEIYSQVQS KKKILATPPQ EDAPSVDIAN 
IRMPTPPSYK VGDKIATRKA YGLALAKLGH ASDRIIALDG DTKNSTFSEL FKKEHPDRFI 
ECYIAEQNMV SIAVGCATRD RTVPFCSTFA AFFTRAFDQI RMAAISESNI NLCGSHCGVS 
IGEDGPSQMA LEDLAMFRSV PMSTVFYPSD GVATEKAVEL AANTKGICFI RTSRPENAII 
YSNNEDFQVG QAKVVLKSKD DQVTVIGAGV TLHEALAAAE SLKKDKISIR VLDPFTIKPL 
DRKLILDSAR ATKGRILTVE DHYYEGGIGE AVSAAVVGEP GVTVTRLAVS QVPRSGKPAE 
LLKMFGIDKD AIVQAVKGLV TKG

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Tkt

Associated with

Other Information

Amplification of the transketolase gene in desensitization-resistant mutant Y1 mouse adrenocortical tumor cells. PubMed ID: 8617775

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

The mouse transketolase (TKT) gene: cloning, characterization, and functional promoter analysis. PubMed ID: 9521875

Immunoaffinity profiling of tyrosine phosphorylation in cancer cells. PubMed ID: 15592455

Large-scale identification and evolution indexing of tyrosine phosphorylation sites from murine brain. PubMed ID: 18034455

A tissue-specific atlas of mouse protein phosphorylation and expression. PubMed ID: 21183079

SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways. PubMed ID: 23806337