Genular: Defining Cellular Identity and Function

Details for: Nr2e1

Gene ID: 21907

Symbol: Nr2e1

Ensembl ID: ENSMUSG00000019803

Description: nuclear receptor subfamily 2, group E, member 1

Associated with

Gene expression (transcription)
(R-MMU-74160)
Generic transcription pathway
(R-MMU-212436)
Nuclear receptor transcription pathway
(R-MMU-383280)
Rna polymerase ii transcription
(R-MMU-73857)
Aggressive behavior
(GO:0002118)
Amygdala development
(GO:0021764)
Anatomical structure development
(GO:0048856)
Angiogenesis
(GO:0001525)
Anterior commissure morphogenesis
(GO:0021960)
Apoptotic process
(GO:0006915)
Astrocyte cell migration
(GO:0043615)
Astrocyte differentiation
(GO:0048708)
Behavioral fear response
(GO:0001662)
Brain development
(GO:0007420)
Camera-type eye development
(GO:0043010)
Cell cycle
(GO:0007049)
Cell differentiation
(GO:0030154)
Cell fate commitment
(GO:0045165)
Cell population proliferation
(GO:0008283)
Cerebral cortex development
(GO:0021987)
Cerebral cortex neuron differentiation
(GO:0021895)
Dentate gyrus development
(GO:0021542)
Dna-binding transcription activator activity, rna polymerase ii-specific
(GO:0001228)
Dna-binding transcription factor activity
(GO:0003700)
Dna-binding transcription repressor activity, rna polymerase ii-specific
(GO:0001227)
Dna binding
(GO:0003677)
Enzyme binding
(GO:0019899)
Extracellular matrix organization
(GO:0030198)
Forebrain generation of neurons
(GO:0021872)
Histone deacetylase binding
(GO:0042826)
Layer formation in cerebral cortex
(GO:0021819)
Long-term synaptic potentiation
(GO:0060291)
Metal ion binding
(GO:0046872)
Multicellular organism development
(GO:0007275)
Negative regulation of apoptotic process
(GO:0043066)
Negative regulation of astrocyte differentiation
(GO:0048712)
Negative regulation of neural precursor cell proliferation
(GO:2000178)
Negative regulation of neuron differentiation
(GO:0045665)
Negative regulation of transcription by rna polymerase ii
(GO:0000122)
Neural precursor cell proliferation
(GO:0061351)
Neuroblast proliferation
(GO:0007405)
Neuron differentiation
(GO:0030182)
Nuclear receptor activity
(GO:0004879)
Nucleoplasm
(GO:0005654)
Nucleus
(GO:0005634)
Olfactory bulb development
(GO:0021772)
Positive regulation of angiogenesis
(GO:0045766)
Positive regulation of cell cycle
(GO:0045787)
Positive regulation of cell population proliferation
(GO:0008284)
Positive regulation of neural precursor cell proliferation
(GO:2000179)
Positive regulation of neuroblast proliferation
(GO:0002052)
Positive regulation of stem cell proliferation
(GO:2000648)
Protein binding
(GO:0005515)
Regulation of cell migration involved in sprouting angiogenesis
(GO:0090049)
Regulation of cellular component organization
(GO:0051128)
Regulation of dendrite morphogenesis
(GO:0048814)
Regulation of dna-templated transcription
(GO:0006355)
Regulation of timing of neuron differentiation
(GO:0060164)
Retina development in camera-type eye
(GO:0060041)
Rna polymerase ii cis-regulatory region sequence-specific dna binding
(GO:0000978)
Sequence-specific dna binding
(GO:0043565)
Sequence-specific double-stranded dna binding
(GO:1990837)
Social behavior
(GO:0035176)
Somatic stem cell population maintenance
(GO:0035019)
Visual perception
(GO:0007601)
Zinc ion binding
(GO:0008270)

Other Information

Proteins

Nuclear receptor subfamily 2 group E member 1

Genular Protein ID: 2661402638

Symbol: NR2E1_MOUSE

Name: Nuclear receptor subfamily 2 group E member 1

UniProtKB Accession Codes:

Q64104

Database IDs:

Citations:

PubMed ID: 7720587

Title: The mouse homolog of the orphan nuclear receptor tailless is expressed in the developing forebrain.

PubMed ID: 7720587

DOI: 10.1242/dev.121.3.839

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 10706625

Title: The orphan nuclear receptor Tlx regulates Pax2 and is essential for vision.

PubMed ID: 10706625

DOI: 10.1073/pnas.050566897

PubMed ID: 11997145

Title: Fierce: a new mouse deletion of Nr2e1; violent behaviour and ocular abnormalities are background-dependent.

PubMed ID: 11997145

DOI: 10.1016/s0166-4328(01)00413-2

PubMed ID: 16702404

Title: Nuclear receptor TLX prevents retinal dystrophy and recruits the corepressor atrophin1.

PubMed ID: 16702404

DOI: 10.1101/gad.1413606

PubMed ID: 17901127

Title: Nuclear receptor TLX regulates cell cycle progression in neural stem cells of the developing brain.

PubMed ID: 17901127

DOI: 10.1210/me.2007-0290

Sequence Information:

Length: 385
Mass: 42619
Checksum: BCEFE4F2163691AC
Sequence:

MSKPAGSTSR ILDIPCKVCG DRSSGKHYGV YACDGCSGFF KRSIRRNRTY VCKSGNQGGC 
PVDKTHRNQC RACRLKKCLE VNMNKDAVQH ERGPRTSTIR KQVALYFRGH KEDNGAAAHF 
PSTALPAPAF FTAVTQLEPH GLELAAVSAT PERQTLVSLA QPTPKYPHEV NGTPMYLYEV 
ATESVCESAA RLLFMSIKWA KSVPAFSTLS LQDQLMLLED AWRELFVLGI AQWAIPVDAN 
TLLAVSGMNT DNTDSQKLNK IISEIQALQE VVARFRQLRL DATEFACLKC IVTFKAVPTH 
SGSELRSFRN AAAIAALQDE AQLTLNSYIH TRYPTQPCRF GKLLLLLPAL RSISPSTIEE 
VFFKKTIGNV PITRLLSDMY KSSDI

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Nr2e1

Associated with

Other Information

The mouse homolog of the orphan nuclear receptor tailless is expressed in the developing forebrain. PubMed ID: 7720587

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

The orphan nuclear receptor Tlx regulates Pax2 and is essential for vision. PubMed ID: 10706625

Fierce: a new mouse deletion of Nr2e1; violent behaviour and ocular abnormalities are background-dependent. PubMed ID: 11997145

Nuclear receptor TLX prevents retinal dystrophy and recruits the corepressor atrophin1. PubMed ID: 16702404