Genular: Defining Cellular Identity and Function

Details for: Tnfrsf10b

Gene ID: 21933

Symbol: Tnfrsf10b

Ensembl ID: ENSMUSG00000022074

Description: tumor necrosis factor receptor superfamily, member 10b

Associated with

Apoptosis
(R-MMU-109581)
Casp8 activity is inhibited
(R-MMU-5218900)
Caspase activation via death receptors in the presence of ligand
(R-MMU-140534)
Caspase activation via extrinsic apoptotic signalling pathway
(R-MMU-5357769)
Cell surface interactions at the vascular wall
(R-MMU-202733)
Death receptor signaling
(R-MMU-73887)
Dimerization of procaspase-8
(R-MMU-69416)
Hemostasis
(R-MMU-109582)
Programmed cell death
(R-MMU-5357801)
Regulated necrosis
(R-MMU-5218859)
Regulation by c-flip
(R-MMU-3371378)
Regulation of necroptotic cell death
(R-MMU-5675482)
Ripk1-mediated regulated necrosis
(R-MMU-5213460)
Trail signaling
(R-MMU-75158)
Apoptotic process
(GO:0006915)
Cell surface
(GO:0009986)
Cysteine-type endopeptidase activator activity involved in apoptotic process
(GO:0008656)
Cytosol
(GO:0005829)
Extrinsic apoptotic signaling pathway via death domain receptors
(GO:0008625)
Golgi apparatus
(GO:0005794)
Identical protein binding
(GO:0042802)
Membrane
(GO:0016020)
Membrane raft
(GO:0045121)
Plasma membrane
(GO:0005886)
Positive regulation of apoptotic process
(GO:0043065)
Protease binding
(GO:0002020)
Regulation of apoptotic process
(GO:0042981)
Signal transduction
(GO:0007165)
Trail-activated apoptotic signaling pathway
(GO:0036462)
Trail binding
(GO:0045569)
Trail receptor activity
(GO:0036463)

Other Information

Proteins

Tumor necrosis factor receptor superfamily member 10B

Genular Protein ID: 3636380886

Symbol: TR10B_MOUSE

Name: Tumor necrosis factor receptor superfamily member 10B

UniProtKB Accession Codes:

Q9QZM4 Q6GSD9 Q9JJL5 Q9JJL6

Database IDs:

Citations:

PubMed ID: 10383128

Title: Molecular cloning and functional analysis of the mouse homologue of the KILLER/DR5 tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) death receptor.

PubMed ID: 10383128

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 30902834

Title: Salmonella effectors SseK1 and SseK3 target death domain proteins in the TNF and TRAIL signaling pathways.

PubMed ID: 30902834

DOI: 10.1074/mcp.ra118.001093

Sequence Information:

Length: 381
Mass: 42165
Checksum: 222531758F4ADE0A
Sequence:

MEPPGPSTPT ASAAARADHY TPGLRPLPKR RLLYSFALLL AVLQAVFVPV TANPAHNRPA 
GLQRPEESPS RGPCLAGQYL SEGNCKPCRE GIDYTSHSNH SLDSCILCTV CKEDKVVETR 
CNITTNTVCR CKPGTFEDKD SPEICQSCSN CTDGEEELTS CTPRENRKCV SKTAWASWHK 
LGLWIGLLVP VVLLIGALLV WKTGAWRQWL LCIKRGCERD PESANSVHSS LLDRQTSSTT 
NDSNHNTEPG KTQKTGKKLL VPVNGNDSAD DLKFIFEYCS DIVPFDSWNR LMRQLGLTDN 
QIQMVKAETL VTREALYQML LKWRHQTGRS ASINHLLDAL EAVEERDAME KIEDYAVKSG 
RFTYQNAAAQ PETGPGGSQC V

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Tnfrsf10b

Associated with

Other Information

Molecular cloning and functional analysis of the mouse homologue of the KILLER/DR5 tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) death receptor. PubMed ID: 10383128

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Salmonella effectors SseK1 and SseK3 target death domain proteins in the TNF and TRAIL signaling pathways. PubMed ID: 30902834

Database document:

PubMed ID: 10383128

PubMed ID: 16141072

PubMed ID: 15489334

PubMed ID: 30902834