Genular: Defining Cellular Identity and Function

Details for: Tnfrsf1b

Gene ID: 21938

Symbol: Tnfrsf1b

Ensembl ID: ENSMUSG00000028599

Description: tumor necrosis factor receptor superfamily, member 1b

Associated with

Cytokine signaling in immune system
(R-MMU-1280215)
Immune system
(R-MMU-168256)
Innate immune system
(R-MMU-168249)
Neutrophil degranulation
(R-MMU-6798695)
Tnfr2 non-canonical nf-kb pathway
(R-MMU-5668541)
Tnfs bind their physiological receptors
(R-MMU-5669034)
Aortic valve development
(GO:0003176)
Axon
(GO:0030424)
Cell surface receptor signaling pathway
(GO:0007166)
Cellular response to lipopolysaccharide
(GO:0071222)
Extrinsic apoptotic signaling pathway
(GO:0097191)
Glial cell-neuron signaling
(GO:0150098)
Immune response
(GO:0006955)
Inflammatory response
(GO:0006954)
Intrinsic apoptotic signaling pathway in response to dna damage
(GO:0008630)
Membrane
(GO:0016020)
Membrane raft
(GO:0045121)
Negative regulation of cardiac muscle hypertrophy
(GO:0010614)
Negative regulation of extracellular matrix constituent secretion
(GO:0003332)
Negative regulation of inflammatory response
(GO:0050728)
Negative regulation of neuroinflammatory response
(GO:0150079)
Neuronal cell body
(GO:0043025)
Perinuclear region of cytoplasm
(GO:0048471)
Positive regulation of apoptotic process involved in morphogenesis
(GO:1902339)
Positive regulation of membrane protein ectodomain proteolysis
(GO:0051044)
Positive regulation of myelination
(GO:0031643)
Positive regulation of oligodendrocyte differentiation
(GO:0048714)
Protein binding
(GO:0005515)
Pulmonary valve development
(GO:0003177)
Regulation of cytokine production involved in immune response
(GO:0002718)
Regulation of myelination
(GO:0031641)
Regulation of neuroinflammatory response
(GO:0150077)
Regulation of t cell cytokine production
(GO:0002724)
Regulation of t cell proliferation
(GO:0042129)
Rna destabilization
(GO:0050779)
Tumor necrosis factor binding
(GO:0043120)
Tumor necrosis factor receptor activity
(GO:0005031)
Ubiquitin protein ligase binding
(GO:0031625)
Varicosity
(GO:0043196)

Other Information

Proteins

Tumor necrosis factor receptor superfamily member 1B

Genular Protein ID: 600729957

Symbol: TNR1B_MOUSE

Name: Tumor necrosis factor receptor superfamily member 1B

UniProtKB Accession Codes:

P25119 O88734 P97893

Database IDs:

Citations:

PubMed ID: 1849278

Title: Cloning and expression of cDNAs for two distinct murine tumor necrosis factor receptors demonstrate one receptor is species specific.

PubMed ID: 1849278

DOI: 10.1073/pnas.88.7.2830

PubMed ID: 1645445

Title: Molecular cloning and expression of the type 1 and type 2 murine receptors for tumor necrosis factor.

PubMed ID: 1645445

DOI: 10.1128/mcb.11.6.3020-3026.1991

PubMed ID: 9740674

Title: The mouse tumor necrosis factor receptor 2 gene: genomic structure and characterization of the two transcripts.

PubMed ID: 9740674

DOI: 10.1006/geno.1998.5407

Sequence Information:

Length: 474
Mass: 50320
Checksum: 462EAE398C4D6563
Sequence:

MAPAALWVAL VFELQLWATG HTVPAQVVLT PYKPEPGYEC QISQEYYDRK AQMCCAKCPP 
GQYVKHFCNK TSDTVCADCE ASMYTQVWNQ FRTCLSCSSS CTTDQVEIRA CTKQQNRVCA 
CEAGRYCALK THSGSCRQCM RLSKCGPGFG VASSRAPNGN VLCKACAPGT FSDTTSSTDV 
CRPHRICSIL AIPGNASTDA VCAPESPTLS AIPRTLYVSQ PEPTRSQPLD QEPGPSQTPS 
ILTSLGSTPI IEQSTKGGIS LPIGLIVGVT SLGLLMLGLV NCIILVQRKK KPSCLQRDAK 
VPHVPDEKSQ DAVGLEQQHL LTTAPSSSSS SLESSASAGD RRAPPGGHPQ ARVMAEAQGF 
QEARASSRIS DSSHGSHGTH VNVTCIVNVC SSSDHSSQCS SQASATVGDP DAKPSASPKD 
EQVPFSQEEC PSQSPCETTE TLQSHEKPLP LGVPDMGMKP SQAGWFDQIA VKVA

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.