Genular: Defining Cellular Identity and Function

Details for: Tnks

Gene ID: 21951

Symbol: Tnks

Ensembl ID: ENSMUSG00000031529

Description: tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase

Associated with

Degradation of axin
(R-MMU-4641257)
Deubiquitination
(R-MMU-5688426)
Intracellular signaling by second messengers
(R-MMU-9006925)
Metabolism of proteins
(R-MMU-392499)
Pip3 activates akt signaling
(R-MMU-1257604)
Post-translational protein modification
(R-MMU-597592)
Pten regulation
(R-MMU-6807070)
Regulation of pten stability and activity
(R-MMU-8948751)
Signaling by wnt
(R-MMU-195721)
Signal transduction
(R-MMU-162582)
Tcf dependent signaling in response to wnt
(R-MMU-201681)
Ub-specific processing proteases
(R-MMU-5689880)
Cell cycle
(GO:0007049)
Cell division
(GO:0051301)
Chromosome
(GO:0005694)
Chromosome, telomeric region
(GO:0000781)
Cytoplasm
(GO:0005737)
Cytoskeleton
(GO:0005856)
Cytosol
(GO:0005829)
Glycosyltransferase activity
(GO:0016757)
Golgi apparatus
(GO:0005794)
Histone binding
(GO:0042393)
Membrane
(GO:0016020)
Metal ion binding
(GO:0046872)
Mitotic spindle pole
(GO:0097431)
Mrna transport
(GO:0051028)
Nad+-protein adp-ribosyltransferase activity
(GO:1990404)
Nad+ adp-ribosyltransferase activity
(GO:0003950)
Negative regulation of maintenance of mitotic sister chromatid cohesion, telomeric
(GO:1904908)
Negative regulation of telomere maintenance via telomere lengthening
(GO:1904357)
Negative regulation of telomeric dna binding
(GO:1904743)
Nuclear body
(GO:0016604)
Nuclear membrane
(GO:0031965)
Nuclear pore
(GO:0005643)
Nucleoplasm
(GO:0005654)
Nucleotidyltransferase activity
(GO:0016779)
Nucleus
(GO:0005634)
Peptidyl-serine phosphorylation
(GO:0018105)
Peptidyl-threonine phosphorylation
(GO:0018107)
Positive regulation of canonical wnt signaling pathway
(GO:0090263)
Positive regulation of telomerase activity
(GO:0051973)
Positive regulation of telomere capping
(GO:1904355)
Positive regulation of telomere maintenance via telomerase
(GO:0032212)
Positive regulation of transcription by rna polymerase ii
(GO:0045944)
Protein auto-adp-ribosylation
(GO:0070213)
Protein localization to chromosome, telomeric region
(GO:0070198)
Protein poly-adp-ribosylation
(GO:0070212)
Protein polyubiquitination
(GO:0000209)
Protein transport
(GO:0015031)
Transferase activity
(GO:0016740)
Wnt signaling pathway
(GO:0016055)
Zinc ion binding
(GO:0008270)

Other Information

Proteins

ADP-ribosyltransferase diphtheria toxin-like 5

Genular Protein ID: 1726422977

Symbol: TNKS1_MOUSE

Name: ADP-ribosyltransferase diphtheria toxin-like 5

UniProtKB Accession Codes:

Q6PFX9 Q8BX62

Database IDs:

Citations:

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 19468303

Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.

PubMed ID: 19468303

DOI: 10.1371/journal.pbio.1000112

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

Sequence Information:

Length: 1320
Mass: 140944
Checksum: A90360DC665FFCC0
Sequence:

MAASRRSQHH HHHHQQQLQP APGASAPPPP PPPPLSPGLA PGPTPASPTA GGLAPFASPR 
HGLALPEGDG SRDPPDRPRS PDPVDGAVCT VAAPAAVPAA SAAVGVAPTP AGGGGGGGNN 
SASSASSPTS SSSSSPSSPG SSLAESPEAA GVGSTATLGA GAAGLGPGVP AVSGALRELL 
EACRNGDVSR VKRLVDAANV NAKDMAGRKS SPLHFAAGFG RKDVVEHLLQ MGANVHARDD 
GGLIPLHNAC SFGHAEVVSL LLCQGADPNA RDNWNYTPLH EAAIKGKIDV CIVLLQHGAD 
PNIRNTDGKS ALDLADPSAK AVLTGEYKKD ELLEAARSGN EEKLMALLTP LNVNCHASDG 
RKSTPLHLAA GYNRVRIVQL LLQHGADVHA KDKGGLVPLH NACSYGHYEV TELLLKHGAC 
VNAMDLWQFT PLHEAASKNR VEVCSLLLSH GADPTLVNCH GKSAVDMAPT PELRERLTYE 
FKGHSLLQAA READLAKVKK TLALEIINFK QPQSHETALH CAVASLHPKR KQVAELLLRK 
GANVNEKNKD FMTPLHVAAE RAHNDVMEVL HKHGAKMNAL DSLGQTALHR AALAGHLQTC 
RLLLSYGSDP SIISLQGFTA AQMGNEAVQQ ILSESTPMRT SDVDYRLLEA SKAGDLETVK 
QLCSPQNVNC RDLEGRHSTP LHFAAGYNRV SVVEYLLHHG ADVHAKDKGG LVPLHNACSY 
GHYEVAELLV RHGASVNVAD LWKFTPLHEA AAKGKYEICK LLLKHGADPT KKNRDGNTPL 
DLVKEGDTDI QDLLRGDAAL LDAAKKGCLA RVQKLCTPEN INCRDTQGRN STPLHLAAGY 
NNLEVAEYLL EHGADVNAQD KGGLIPLHNA ASYGHVDIAA LLIKYNTCVN ATDKWAFTPL 
HEAAQKGRTQ LCALLLAHGA DPTMKNQEGQ TPLDLATADD IRALLIDAMP PEALPTCFKP 
QATVVSASLI SPASTPSCLS AASSIDNLTG PLTDLAVGGA SNAGDGAAGA ERKEGEVAGL 
DMNISQFLKS LGLEHLRDIF ETEQITLDVL ADMGHEELKE IGINAYGHRH KLIKGVERLL 
GGQQGTNPYL TFHCVNQGTI LLDLAPEDKE YQSVEEEMQS TIREHRDGGN AGGIFNRYNV 
IRIQKVVNKK LRERFCHRQK EVSEENHNHH NERMLFHGSP FINAIIHKGF DERHAYIGGM 
FGAGIYFAEN SSKSNQYVYG IGGGTGCPTH KDRSCYICHR QMLFCRVTLG KSFLQFSTMK 
MAHAPPGHHS VIGRPSVNGL AYAEYVIYRG EQAYPEYLIT YQIMKPEAPS QTATAAEQKT

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.