Details for: Tnp2

Gene ID: 21959

Symbol: Tnp2

Ensembl ID: ENSMUSG00000043050

Description: transition protein 2

Associated with

Other Information

Genular Protein ID: 1802455935

Symbol: STP2_MOUSE

Name: Nuclear transition protein 2

UniProtKB Accession Codes:

P11378 Q91XK4

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CCDS 1 CTD 1 ChEBI 8 ChiTaRS 1 DNASU 1 EMBL 8 Ensembl 1 GO 12 GeneTree 1 InParanoid 1 InterPro 1 KEGG 1 MGI 2 NCBI Taxonomy 1 OMA 1 PANTHER 2 PIR 1 PRO 1 PROSITE 2 PaxDb 1 Pfam 1 PhosphoSitePlus 1 Proteomes 1 ProteomicsDB 1 RNAct 1 RefSeq 1 SAM 1 SMR 1 STRING 1 SwissPalm 1 UCSC 1 UniProtKB 1 VEuPathDB 1 eggNOG 1 iPTMnet 1

Citations:

PubMed ID: 2249785

Title: Nucleotide sequence of the gene encoding mouse transition protein 2.

PubMed ID: 2249785

DOI: 10.1016/0378-1119(90)90376-3

PubMed ID: 3693351

Title: Characterization of a cDNA clone encoding a basic protein, TP2, involved in chromatin condensation during spermiogenesis in the mouse.

PubMed ID: 3693351

DOI: 10.1016/s0021-9258(18)45373-2

PubMed ID: 8720108

Title: Sequence analysis of the conserved protamine gene cluster shows that it contains a fourth expressed gene.

PubMed ID: 8720108

DOI: 10.1002/(sici)1098-2795(199601)43:1<1::aid-mrd1>3.0.co;2-w

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 19468303

Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.

PubMed ID: 19468303

DOI: 10.1371/journal.pbio.1000112

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 15163613

Title: Nucleoprotein transitions during spermiogenesis in mice with transition nuclear protein Tnp1 and Tnp2 mutations.

PubMed ID: 15163613

DOI: 10.1095/biolreprod.104.028191

PubMed ID: 15189834

Title: Abnormalities and reduced reproductive potential of sperm from Tnp1- and Tnp2-null double mutant mice.

PubMed ID: 15189834

DOI: 10.1095/biolreprod.104.029363

PubMed ID: 15083521

Title: Transition nuclear proteins are required for normal chromatin condensation and functional sperm development.

PubMed ID: 15083521

DOI: 10.1002/gene.20019

PubMed ID: 28366643

Title: Histone variant H2A.L.2 guides transition protein-dependent protamine assembly in male germ cells.

PubMed ID: 28366643

DOI: 10.1016/j.molcel.2017.02.025

Sequence Information:

  • Length: 117
  • Mass: 13117
  • Checksum: F5692E66E5F3F2CA
  • Sequence:
    • MDTKMQSLPT THPHPHSSSR PQSHTSNQCN QCTCSHHCRS CSQAGHAGSS SSPSPGPPMK 
HPKPSVHSRH SPARPSHRGS CPKNRKTFEG KVSKRKAVRR RKRTHRAKRR SSGRRYK

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.