Details for: ALDH1A3

Gene ID: 220

Symbol: ALDH1A3

Ensembl ID: ENSG00000184254

Description: aldehyde dehydrogenase 1 family member A3

Associated with

Other Information

Genular Protein ID: 3587866517

Symbol: AL1A3_HUMAN

Name: Retinaldehyde dehydrogenase 3

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 7698756

Title: Molecular cloning, genomic organization, and chromosomal localization of an additional human aldehyde dehydrogenase gene, ALDH6.

PubMed ID: 7698756

DOI: 10.1006/geno.1994.1624

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 22814378

Title: N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.

PubMed ID: 22814378

DOI: 10.1073/pnas.1210303109

PubMed ID: 23591992

Title: ALDH1A3 loss of function causes bilateral anophthalmia/microphthalmia and hypoplasia of the optic nerve and optic chiasm.

PubMed ID: 23591992

DOI: 10.1093/hmg/ddt179

PubMed ID: 27759097

Title: Crystal structure of human aldehyde dehydrogenase 1A3 complexed with NAD(+) and retinoic acid.

PubMed ID: 27759097

DOI: 10.1038/srep35710

PubMed ID: 23312594

Title: ALDH1A3 mutations cause recessive anophthalmia and microphthalmia.

PubMed ID: 23312594

DOI: 10.1016/j.ajhg.2012.12.003

PubMed ID: 23646827

Title: Mutations in ALDH1A3 cause Microphthalmia.

PubMed ID: 23646827

DOI: 10.1111/cge.12184

PubMed ID: 24568872

Title: Novel splice-site and missense mutations in the ALDH1A3 gene underlying autosomal recessive anophthalmia/microphthalmia.

PubMed ID: 24568872

DOI: 10.1136/bjophthalmol-2013-304058

PubMed ID: 24024553

Title: A homozygous mutation in a consanguineous family consolidates the role of ALDH1A3 in autosomal recessive microphthalmia.

PubMed ID: 24024553

DOI: 10.1111/cge.12277

PubMed ID: 23881059

Title: A missense mutation in ALDH1A3 causes isolated microphthalmia/anophthalmia in nine individuals from an inbred Muslim kindred.

PubMed ID: 23881059

DOI: 10.1038/ejhg.2013.157

PubMed ID: 24777706

Title: Mutations in ALDH1A3 represent a frequent cause of microphthalmia/anophthalmia in consanguineous families.

PubMed ID: 24777706

DOI: 10.1002/humu.22580

Sequence Information:

  • Length: 512
  • Mass: 56108
  • Checksum: 1BFCF4F56F0FE89A
  • Sequence:
  • MATANGAVEN GQPDRKPPAL PRPIRNLEVK FTKIFINNEW HESKSGKKFA TCNPSTREQI 
    CEVEEGDKPD VDKAVEAAQV AFQRGSPWRR LDALSRGRLL HQLADLVERD RATLAALETM 
    DTGKPFLHAF FIDLEGCIRT LRYFAGWADK IQGKTIPTDD NVVCFTRHEP IGVCGAITPW 
    NFPLLMLVWK LAPALCCGNT MVLKPAEQTP LTALYLGSLI KEAGFPPGVV NIVPGFGPTV 
    GAAISSHPQI NKIAFTGSTE VGKLVKEAAS RSNLKRVTLE LGGKNPCIVC ADADLDLAVE 
    CAHQGVFFNQ GQCCTAASRV FVEEQVYSEF VRRSVEYAKK RPVGDPFDVK TEQGPQIDQK 
    QFDKILELIE SGKKEGAKLE CGGSAMEDKG LFIKPTVFSE VTDNMRIAKE EIFGPVQPIL 
    KFKSIEEVIK RANSTDYGLT AAVFTKNLDK ALKLASALES GTVWINCYNA LYAQAPFGGF 
    KMSGNGRELG EYALAEYTEV KTVTIKLGDK NP

Genular Protein ID: 732464347

Symbol: H0Y2X5_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 11181995

Title: The sequence of the human genome.

PubMed ID: 11181995

DOI: 10.1126/science.1058040

PubMed ID: 16572171

Title: Analysis of the DNA sequence and duplication history of human chromosome 15.

PubMed ID: 16572171

DOI: 10.1038/nature04601

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 22814378

Title: N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.

PubMed ID: 22814378

DOI: 10.1073/pnas.1210303109

Sequence Information:

  • Length: 405
  • Mass: 44256
  • Checksum: CE65AE95A0149C63
  • Sequence:
  • MATANGAVEN GQPDRKPPAL PRPIRNLEVK FTKIFINNEW HESKSGKKFA TCNPSTREQI 
    CEVEEGDKPD VDKAVEAAQV AFQRGSPWRR LDALSRGRLL HQLADLVERD RATLAAGFPP 
    GVVNIVPGFG PTVGAAISSH PQINKIAFTG STEVGKLVKE AASRSNLKRV TLELGGKNPC 
    IVCADADLDL AVECAHQGVF FNQGQCCTAA SRVFVEEQVY SEFVRRSVEY AKKRPVGDPF 
    DVKTEQGPQI DQKQFDKILE LIESGKKEGA KLECGGSAME DKGLFIKPTV FSEVTDNMRI 
    AKEEIFGPVQ PILKFKSIEE VIKRANSTDY GLTAAVFTKN LDKALKLASA LESGTVWINC 
    YNALYAQAPF GGFKMSGNGR ELGEYALAEY TEVKTVTIKL GDKNP

Genular Protein ID: 3225247372

Symbol: Q7Z3A2_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Sequence Information:

  • Length: 416
  • Mass: 45435
  • Checksum: BBF5DB0FA5C68D6D
  • Sequence:
  • RAPRARERGG AMATANGAVE NGQPDRKPPA LPRPIRNLEV KFTKIFINNE WHESKSGKKF 
    ATCNPSTREQ ICEVEEGDKP DVDKAVEAAQ VAFQRGSPWR RLDALSRGRL LHQLADLVER 
    DRATLAAGFP PGVVNIVPGF GPTVGAAISS HPQINKIAFT GSTEVGKLVK EAASRSNLKR 
    VTLELGGKNP CIVCADADLD LAVECAHQGV FFNQGQCCTA ASRVFVEEQV YSEFVRRSVE 
    YAKKRPVGDP FDVKTEQGPQ IDQKQFDKIL ELIESGKKEG AKLECGGSAM EDKGLFIKPT 
    VFSEVTDNMR IAKEEIFGPV QPILKFKSIE EVIKRANSTD YGLTAAVFTK NLDKALKLAS 
    ALESGTVWIN CYNALYAQAP FGGFKMSGNG RELGEYALAE YTEVKTVTIK LGDKNP

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.